1HX0

Structure of pig pancreatic alpha-amylase complexed with the "truncate" acarbose molecule (pseudotrisaccharide)

Summary for 1HX0

Entry DOI	10.2210/pdb1hx0/pdb
Related PRD ID	PRD_900001
Descriptor	ALPHA AMYLASE (PPA), 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (7 entities in total)
Functional Keywords	alpha-amylase, inhibitor, carbohydrate, pancreas, hydrolase
Biological source	Sus scrofa (pig)
Total number of polymer chains	1
Total formula weight	57690.74
Authors	Qian, M.,Payan, F. (deposition date: 2001-01-11, release date: 2001-08-08, Last modification date: 2023-10-25)
Primary citation	Qian, M.,Nahoum, V.,Bonicel, J.,Bischoff, H.,Henrissat, B.,Payan, F. Enzyme-catalyzed condensation reaction in a mammalian alpha-amylase. High-resolution structural analysis of an enzyme-inhibitor complex Biochemistry, 40:7700-7709, 2001 Cited by PubMed: 11412124 DOI: 10.1021/bi0102050 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.38 Å)

Structure validation