1HX0
Structure of pig pancreatic alpha-amylase complexed with the "truncate" acarbose molecule (pseudotrisaccharide)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALPHA AMYLASE (PPA) | polymer | 496 | 55472.8 | 1 | UniProt (P00690) Pfam (PF00128) Pfam (PF02806) | Sus scrofa (pig) | |
| 2 | B (B) | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 948.9 | 1 | In PDB GlyTouCan (G53811MA) | |||
| 3 | C (C) | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 1 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
| 4 | D, E, G, H (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | I, J, K, L, M... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 7 | U (A) | water | water | 18.0 | 921 | Chemie (HOH) |
Sequence modifications
A: 1 - 496 (UniProt: P00690)
| PDB | External Database | Details |
|---|---|---|
| Asn 123 | Ser 138 | conflict |
| Lys 243 | Gln 258 | conflict |
| Ser 310 | Ala 325 | conflict |
| Ile 323 | Val 338 | conflict |
| Gln 404 | Glu 419 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 55472.8 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1291.2 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 926.7 | |
| All* | Total formula weight | 57690.7 |
