1FS3
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7R1P
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7QPY
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4WYZ
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![BU of 4wyz by Molmil](/molmil-images/mine/4wyz) | The crystal structure of the A109G mutant of RNase A in complex with 3'UMP | Descriptor: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | Authors: | French, R.L, Gagne, D, Doucet, N, Simonovic, M. | Deposit date: | 2014-11-18 | Release date: | 2015-11-18 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity. Structure, 23, 2015
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6XHF
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![BU of 6xhf by Molmil](/molmil-images/mine/6xhf) | Structure of Phenylalanyl-5'-O-adenosine phosphoramidate | Descriptor: | (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, Ribonuclease pancreatic | Authors: | Pallan, P.S, Egli, M. | Deposit date: | 2020-06-18 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angew.Chem.Int.Ed.Engl., 59, 2020
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7QPZ
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7Z6D
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3RN3
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![BU of 3rn3 by Molmil](/molmil-images/mine/3rn3) | SEGMENTED ANISOTROPIC REFINEMENT OF BOVINE RIBONUCLEASE A BY THE APPLICATION OF THE RIGID-BODY TLS MODEL | Descriptor: | RIBONUCLEASE A, SULFATE ION | Authors: | Howlin, B, Moss, D.S, Harris, G.W, Palmer, R.A. | Deposit date: | 1991-10-30 | Release date: | 1991-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model. Acta Crystallogr.,Sect.A, 45, 1989
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1YMN
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![BU of 1ymn by Molmil](/molmil-images/mine/1ymn) | The study of reductive unfolding pathways of RNase A (Y92L mutant) | Descriptor: | Ribonuclease pancreatic | Authors: | Xu, G, Narayan, M, Kurinov, I, Ripoll, D.R, Welker, E, Khalili, M, Ealick, S.E, Scheraga, H.A. | Deposit date: | 2005-01-21 | Release date: | 2006-01-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | A localized specific interaction alters the unfolding pathways of structural homologues. J.Am.Chem.Soc., 128, 2006
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7Q76
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![BU of 7q76 by Molmil](/molmil-images/mine/7q76) | Room temperature structure of RNase A at 22 MPa helium gas pressure in a sapphire capillary | Descriptor: | CHLORIDE ION, Ribonuclease pancreatic, SODIUM ION, ... | Authors: | Lieske, J, Guenther, S, Saouane, S, Meents, A. | Deposit date: | 2021-11-09 | Release date: | 2022-11-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Fixed-target high-pressure macromolecular crystallography To Be Published
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6PVU
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![BU of 6pvu by Molmil](/molmil-images/mine/6pvu) | RNase A in complex with hexametaphosphate | Descriptor: | 2,4,6,8,10,12-hexahydroxy-2lambda~5~,4lambda~5~,6lambda~5~,8lambda~5~,10lambda~5~,12lambda~5~-cyclohexaphosphoxane-2,4,6,8,10,12-hexone, Ribonuclease pancreatic | Authors: | Windsor, I.W, Sheppard, S.M, Cummins, C.C, Raines, R.T. | Deposit date: | 2019-07-21 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A. J.Am.Chem.Soc., 141, 2019
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3QL2
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3OQY
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9RAT
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7RAT
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2G8Q
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1IZR
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![BU of 1izr by Molmil](/molmil-images/mine/1izr) | F46A mutant of bovine pancreatic ribonuclease A | Descriptor: | RIBONUCLEASE A | Authors: | Kadonosono, T, Chatani, E, Hayashi, R, Moriyama, H, Ueki, T. | Deposit date: | 2002-10-11 | Release date: | 2003-11-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Minimization of cavity size ensures protein stability and folding: structures of Phe46-replaced bovine pancreatic RNase A Biochemistry, 42, 2003
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1RNC
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![BU of 1rnc by Molmil](/molmil-images/mine/1rnc) | NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, RIBONUCLEASE A, SULFATE ION | Authors: | Aguilar, C.F, Thomas, P.J, Mills, A, Moss, D.S, Palmer, R.A. | Deposit date: | 1991-10-21 | Release date: | 1994-01-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Newly observed binding mode in pancreatic ribonuclease. J.Mol.Biol., 224, 1992
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1O0F
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![BU of 1o0f by Molmil](/molmil-images/mine/1o0f) | RNASE A in complex with 3',5'-ADP | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | Deposit date: | 2003-02-21 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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1O0M
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![BU of 1o0m by Molmil](/molmil-images/mine/1o0m) | Ribonuclease A in complex with uridine-2'-phosphate | Descriptor: | PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | Deposit date: | 2003-02-24 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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6RAT
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8OQE
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![BU of 8oqe by Molmil](/molmil-images/mine/8oqe) | Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (6 h soaking) | Descriptor: | CHLORIDE ION, FORMIC ACID, Ribonuclease pancreatic, ... | Authors: | Loreto, D, Merlino, A, Maity, B, Ueno, T. | Deposit date: | 2023-04-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts. Inorg.Chem., 62, 2023
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8OQF
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![BU of 8oqf by Molmil](/molmil-images/mine/8oqf) | Cross-linked crystal of Dirhodium tetraacetate/ribonuclease A adduct in the P3221 space group (low temperature data collection) | Descriptor: | (mi2-acetato-O, O')-hexaaquo-dirhodium (II), CHLORIDE ION, ... | Authors: | Loreto, D, Merlino, A, Maity, B, Ueno, T. | Deposit date: | 2023-04-12 | Release date: | 2023-06-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Cross-Linked Crystals of Dirhodium Tetraacetate/RNase A Adduct Can Be Used as Heterogeneous Catalysts. Inorg.Chem., 62, 2023
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3MZQ
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![BU of 3mzq by Molmil](/molmil-images/mine/3mzq) | RNase crystals grown by the hanging drop method | Descriptor: | CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION | Authors: | Mathews, I.I. | Deposit date: | 2010-05-12 | Release date: | 2011-05-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Diffraction study of protein crystals grown in cryoloops and micromounts. J.Appl.Crystallogr., 43, 2010
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1O0N
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![BU of 1o0n by Molmil](/molmil-images/mine/1o0n) | Ribonuclease A in complex with uridine-3'-phosphate | Descriptor: | 3'-URIDINEMONOPHOSPHATE, Ribonuclease pancreatic | Authors: | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | Deposit date: | 2003-02-24 | Release date: | 2003-12-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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