7XJ6
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![BU of 7xj6 by Molmil](/molmil-images/mine/7xj6) | SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 1 conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 55A8 heavy chain, ... | Authors: | Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X. | Deposit date: | 2022-04-15 | Release date: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (3.29 Å) | Cite: | SARS-CoV-2 BA.1 Spike trimer in complex with 55A8 Fab and 58G6 Fab in the class 1 conformation To Be Published
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7L7K
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![BU of 7l7k by Molmil](/molmil-images/mine/7l7k) | |
8WHU
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![BU of 8whu by Molmil](/molmil-images/mine/8whu) | Spike Trimer of BA.2.86 in complex with two hACE2s | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ... | Authors: | Yue, C, Liu, P. | Deposit date: | 2023-09-23 | Release date: | 2024-07-03 | Last modified: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity. Natl Sci Rev, 11, 2024
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6YZ7
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![BU of 6yz7 by Molmil](/molmil-images/mine/6yz7) | H11-D4, SARS-CoV-2 RBD, CR3022 ternary complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Cr3022, Antibody light chain, ... | Authors: | Naismith, J.H, Ren, J, Zhou, D, Zhao, Y, Stuart, D.I. | Deposit date: | 2020-05-06 | Release date: | 2020-06-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural characterisation of a nanobody derived from a naive library that neutralises SARS-CoV-2 To Be Published, 2020
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7WD0
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![BU of 7wd0 by Molmil](/molmil-images/mine/7wd0) | SARS-CoV-2 Beta spike in complex with two S5D2 Fabs | Descriptor: | Heavy chain of S5D2 Fab, Light chain of S5D2 Fab, Spike glycoprotein | Authors: | Wang, Y.F, Cong, Y. | Deposit date: | 2021-12-20 | Release date: | 2022-02-02 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein. Emerg Microbes Infect, 11, 2022
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6Z43
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![BU of 6z43 by Molmil](/molmil-images/mine/6z43) | Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, ... | Authors: | Ruza, R.R, Duyvesteyn, H.M.E, Shah, P, Carrique, L, Ren, J, Malinauskas, T, Zhou, D, Stuart, D.I, Naismith, J.H. | Deposit date: | 2020-05-22 | Release date: | 2020-06-03 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2 To Be Published
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7TLZ
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![BU of 7tlz by Molmil](/molmil-images/mine/7tlz) | |
7WEA
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![BU of 7wea by Molmil](/molmil-images/mine/7wea) | |
8SUO
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![BU of 8suo by Molmil](/molmil-images/mine/8suo) | BA.2/AZD1061/AZD3152 structure analysis | Descriptor: | AZD1061 heavy chain, AZD1061 light chain, AZD3152 heavy chain, ... | Authors: | Oganesyan, V, van Dyk, N, Dippel, A, Barnes, A, O'Connor, E. | Deposit date: | 2023-05-12 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | X-ray crystal structure of BA.2 RBD bound by two neutralizing antibodies To Be Published
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7WCD
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![BU of 7wcd by Molmil](/molmil-images/mine/7wcd) | Cryo EM structure of SARS-CoV-2 spike in complex with TAU-2212 mAbs in conformation 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain, Light chain, ... | Authors: | Xiang, Y, Ma, B, Li, R. | Deposit date: | 2021-12-19 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Conformational flexibility in neutralization of SARS-CoV-2 by naturally elicited anti-SARS-CoV-2 antibodies. Commun Biol, 5, 2022
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7M6E
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![BU of 7m6e by Molmil](/molmil-images/mine/7m6e) | |
8G7A
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![BU of 8g7a by Molmil](/molmil-images/mine/8g7a) | |
8DT3
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![BU of 8dt3 by Molmil](/molmil-images/mine/8dt3) | Cryo-EM structure of spike binding to Fab of neutralizing antibody (locally refined) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab of SW186, Light chain Fab of SW186, ... | Authors: | Sun, P.C, Fang, Y, Bai, X.C, Chen, Z.J. | Deposit date: | 2022-07-25 | Release date: | 2022-08-03 | Last modified: | 2022-11-09 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | An antibody that neutralizes SARS-CoV-1 and SARS-CoV-2 by binding to a conserved spike epitope outside the receptor binding motif. Sci Immunol, 7, 2022
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7M42
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![BU of 7m42 by Molmil](/molmil-images/mine/7m42) | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 | Descriptor: | REGN10985 antibody Fab fragment heavy chain, REGN10985 antibody Fab fragment light chain, REGN10989 antibody Fab fragment heavy chain, ... | Authors: | Zhou, Y, Romero Hernandez, A, Saotome, K, Franklin, M.C. | Deposit date: | 2021-03-19 | Release date: | 2021-07-28 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies. Cell, 184, 2021
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7EDJ
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![BU of 7edj by Molmil](/molmil-images/mine/7edj) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7) in complex with Angiotensin-converting enzyme 2 (ACE2) ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2 (ACE2) ectodomain, ... | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7EDI
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![BU of 7edi by Molmil](/molmil-images/mine/7edi) | Cryo-EM structure of SARS-CoV-2 S-UK variant (B.1.1.7), two RBD-up conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Yang, T.J, Yu, P.Y, Chang, Y.C, Wu, H.C, Hsu, S.T.D. | Deposit date: | 2021-03-16 | Release date: | 2021-09-01 | Last modified: | 2022-01-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Effect of SARS-CoV-2 B.1.1.7 mutations on spike protein structure and function. Nat.Struct.Mol.Biol., 28, 2021
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7XID
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![BU of 7xid by Molmil](/molmil-images/mine/7xid) | S-ECD (Omicron) in complex with PD of ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2022-04-12 | Release date: | 2022-06-15 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7XIC
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![BU of 7xic by Molmil](/molmil-images/mine/7xic) | S-ECD (Omicron) in complex with STS165 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | Deposit date: | 2022-04-12 | Release date: | 2022-06-15 | Last modified: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7XOB
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![BU of 7xob by Molmil](/molmil-images/mine/7xob) | SARS-CoV-2 Omicron BA.2 Variant Spike Trimer with two mouse ACE2 Bound | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Xu, Y, Wu, C, Liu, H, Yin, W, Xu, H.E. | Deposit date: | 2022-05-01 | Release date: | 2022-06-15 | Last modified: | 2022-07-13 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins. Cell Res., 32, 2022
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8V0X
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7NDA
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![BU of 7nda by Molmil](/molmil-images/mine/7nda) | EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-253H55L Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Duyvesteyn, H.M.E, Zhao, Y, Ren, J, Stuart, D. | Deposit date: | 2021-01-30 | Release date: | 2021-03-03 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The antigenic anatomy of SARS-CoV-2 receptor binding domain. Cell, 184, 2021
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7K9I
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![BU of 7k9i by Molmil](/molmil-images/mine/7k9i) | |
7X93
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![BU of 7x93 by Molmil](/molmil-images/mine/7x93) | |
8ERQ
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![BU of 8erq by Molmil](/molmil-images/mine/8erq) | |
7R12
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![BU of 7r12 by Molmil](/molmil-images/mine/7r12) | Dissociated S1 domain of Mink Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | Deposit date: | 2022-02-02 | Release date: | 2022-03-09 | Last modified: | 2022-03-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
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