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1TUP
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TUMOR SUPPRESSOR P53 COMPLEXED WITH DNA
分子名称: DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR ), ...
著者Cho, Y, Gorina, S, Jeffrey, P.D, Pavletich, N.P.
登録日1995-07-11
公開日1995-07-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
1TSR
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BU of 1tsr by Molmil
P53 CORE DOMAIN IN COMPLEX WITH DNA
分子名称: DNA (5'-D(*AP*TP*AP*AP*TP*TP*GP*GP*GP*CP*AP*AP*GP*TP*CP*TP*A P*GP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*CP*TP*AP*GP*AP*CP*TP*TP*GP*CP*CP*CP*A P*AP*TP*TP*A)-3'), PROTEIN (P53 TUMOR SUPPRESSOR), ...
著者Cho, Y, Gorina, S, Jeffrey, P, Pavletich, N.
登録日1995-07-28
公開日1996-01-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.
Science, 265, 1994
1YCS
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BU of 1ycs by Molmil
P53-53BP2 COMPLEX
分子名称: 53BP2, P53, ZINC ION
著者Gorina, S, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2.
Science, 274, 1996
1C26
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BU of 1c26 by Molmil
CRYSTAL STRUCTURE OF P53 TETRAMERIZATION DOMAIN
分子名称: P53 TUMOR SUPPRESSOR
著者Jeffrey, P.D, Gorina, S, Pavletich, N.P.
登録日1999-07-22
公開日1999-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.
Science, 267, 1995
3DAC
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BU of 3dac by Molmil
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
分子名称: Cellular tumor antigen p53, Mdm4 protein
著者Popowicz, G.M, Czarna, A, Holak, T.A.
登録日2008-05-29
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
Cell Cycle, 7, 2008
3DAB
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BU of 3dab by Molmil
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain
分子名称: Cellular tumor antigen p53, Mdm4 protein
著者Popowicz, G.M, Czarna, A, Holak, T.A.
登録日2008-05-29
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.
Cell Cycle, 7, 2008
3TG5
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BU of 3tg5 by Molmil
Structure of SMYD2 in complex with p53 and SAH
分子名称: Cellular tumor antigen p53, GLYCEROL, N-lysine methyltransferase SMYD2, ...
著者Zhao, K, Wang, L.
登録日2011-08-17
公開日2011-08-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
1YCQ
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BU of 1ycq by Molmil
XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
分子名称: MDM2, P53
著者Kussie, P.H, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1YCR
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BU of 1ycr by Molmil
MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
分子名称: MDM2, P53
著者Kussie, P.H, Pavletich, N.P.
登録日1996-09-30
公開日1997-11-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
2H1L
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BU of 2h1l by Molmil
The Structure of the Oncoprotein SV40 Large T Antigen and p53 Tumor Suppressor Complex
分子名称: Cellular tumor antigen p53, Large T antigen, ZINC ION
著者Lilyestrom, W, Klein, M.G, Chen, X.S.
登録日2006-05-16
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor.
Genes Dev., 20, 2006
7YGI
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BU of 7ygi by Molmil
Crystal structure of p53 DBD domain in complex with azurin
分子名称: Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ...
著者Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q.
登録日2022-07-11
公開日2023-02-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Commun Biol, 6, 2023
2OCJ
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BU of 2ocj by Molmil
Human p53 core domain in the absence of DNA
分子名称: P53 TUMOR SUPPRESSOR, ZINC ION
著者Wang, Y, Rosengarth, A, Luecke, H.
登録日2006-12-20
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the human p53 core domain in the absence of DNA.
Acta Crystallogr.,Sect.D, 63, 2007
1GZH
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BU of 1gzh by Molmil
Crystal structure of the BRCT domains of human 53BP1 bound to the p53 tumor supressor
分子名称: CELLULAR TUMOR ANTIGEN P53, SULFATE ION, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ...
著者Derbyshire, D.J, Doherty, A.J.
登録日2002-05-22
公開日2002-06-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Human 53BP1 Brct Domains Bound to P53 Tumour Suppressor
Embo J., 21, 2002
1UOL
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BU of 1uol by Molmil
Crystal structure of the human p53 core domain mutant M133L/V203A/N239Y/N268D at 1.9 A resolution.
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Allen, M.D, Fersht, A.R.
登録日2003-09-19
公開日2003-10-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of a Superstable Mutant of Human P53 Core Domain. Insights Into the Mechanism of Rescuing Oncogenic Mutations
J.Biol.Chem., 279, 2004
2BIP
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BU of 2bip by Molmil
human p53 core domain mutant M133L-H168R-V203A-N239Y-R249S-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIQ
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BU of 2biq by Molmil
human p53 core domain mutant T123A-M133L-H168R-V203A-N239Y-R249S- N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIN
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BU of 2bin by Molmil
human p53 core domain mutant M133L-H168R-V203A-N239Y-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIO
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BU of 2bio by Molmil
human p53 core domain mutant M133L-V203A-N239Y-R249S-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIM
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BU of 2bim by Molmil
human p53 core domain mutant M133L-V203A-N239Y-N268D-R273H
分子名称: CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
5XZC
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BU of 5xzc by Molmil
Cryo-EM structure of p300-p53 protein complex
分子名称: Cellular tumor antigen p53, Histone acetyltransferase p300
著者Ghosh, R, Roy, S, Sengupta, J.
登録日2017-07-12
公開日2019-01-23
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (10.7 Å)
主引用文献Tumor suppressor p53-mediated structural reorganization of the transcriptional coactivator p300.
Biochemistry, 2019
3TG4
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BU of 3tg4 by Molmil
Structure of SMYD2 in complex with SAM
分子名称: GLYCEROL, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ...
著者Zhao, K, Wang, L.
登録日2011-08-17
公開日2011-08-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of human SMYD2 reveals the basis of p53 tumor suppressor methylation
J.Biol.Chem., 2011
2M86
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BU of 2m86 by Molmil
Solution structure of Hdm2 with engineered cyclotide
分子名称: E3 ubiquitin-protein ligase Mdm2, MCo-PMI
著者Majumder, S, Ji, Y, Millard, M, Borra, R, Bi, T, Elnagar, A.Y, Neamati, N, Camarero, J.A.
登録日2013-05-07
公開日2013-07-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide.
J.Am.Chem.Soc., 135, 2013
1A1U
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BU of 1a1u by Molmil
SOLUTION STRUCTURE DETERMINATION OF A P53 MUTANT DIMERIZATION DOMAIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: P53
著者Mccoy, M.A, Stavridi, E.S, Waterman, J.L.F, Wieczorek, A, Opella, S.J, Halezonetis, T.D.
登録日1997-12-16
公開日1998-04-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Hydrophobic side-chain size is a determinant of the three-dimensional structure of the p53 oligomerization domain.
EMBO J., 16, 1997
1KZY
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BU of 1kzy by Molmil
Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53
分子名称: CELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION
著者Joo, W.S, Jeffrey, P.D, Cantor, S.B, Finnin, M.S, Livingston, D.M, Pavletich, N.P.
登録日2002-02-08
公開日2002-03-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16, 2002
1HU8
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BU of 1hu8 by Molmil
CRYSTAL STRUCTURE OF THE MOUSE P53 CORE DNA-BINDING DOMAIN AT 2.7A RESOLUTION
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Zhao, K, Chai, X, Johnston, K, Clements, A, Marmorstein, R.
登録日2001-01-04
公開日2001-07-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution.
J.Biol.Chem., 276, 2001

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