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6HPJ
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Structure of human SRSF1 RRM1 bound to AACAAA RNA
分子名称: Immunoglobulin G-binding protein G,Serine/arginine-rich splicing factor 1, RNA (5'-R(*AP*AP*CP*AP*AP*A)-3')
著者Allain, F.T.H, Clery, A.
登録日2018-09-21
公開日2020-11-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of SRSF1 RRM1 bound to RNA reveals an unexpected bimodal mode of interaction and explains its involvement in SMN1 exon7 splicing.
Nat Commun, 12, 2021
4RG5
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Crystal Structure of S. Pombe SMN YG-Dimer
分子名称: MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ...
著者Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D.
登録日2014-09-29
公開日2015-07-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oligomeric Properties of Survival Motor NeuronGemin2 Complexes.
J.Biol.Chem., 290, 2015
7BB3
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Structure of S. pombe YG-box oligomer
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Survival motor neuron-like protein 1,Survival motor neuron-like protein 1
著者Veepaschit, J, Grimm, C, Fischer, U.
登録日2020-12-16
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.158 Å)
主引用文献Identification and structural analysis of the Schizosaccharomyces pombe SMN complex.
Nucleic Acids Res., 49, 2021
4QQ6
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Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule
分子名称: 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION
著者Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC)
登録日2014-06-26
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.
Nat Commun, 13, 2022
8BEF
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Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ...
著者Klusch, N, Kuehlbrandt, W.
登録日2022-10-21
公開日2023-01-11
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (2.13 Å)
主引用文献Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BPX
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Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete composition)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ...
著者Klusch, N, Kuehlbrandt, W.
登録日2022-11-18
公開日2023-01-25
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (2.09 Å)
主引用文献Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BQ6
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Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition)
分子名称: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
著者Klusch, N, Kuehlbrandt, W.
登録日2022-11-18
公開日2023-05-10
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
8BQ5
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Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition)
分子名称: 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ...
著者Klusch, N, Kuehlbrandt, W.
登録日2022-11-18
公開日2023-03-22
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
7AQQ
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Cryo-EM structure of Arabidopsis thaliana Complex-I (membrane core)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
著者Klusch, N, Kuehlbrandt, W, Yildiz, O.
登録日2020-10-22
公開日2021-12-08
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
7AR8
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Cryo-EM structure of Arabidopsis thaliana complex-I (closed conformation)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
著者Klusch, N, Kuelbrandt, W, Yildiz, O.
登録日2020-10-23
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
7ARB
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Cryo-EM structure of Arabidopsis thaliana Complex-I (complete composition)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
著者Klusch, N, Kuelbrandt, W, Yildiz, O.
登録日2020-10-23
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
7AR7
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Cryo-EM structure of Arabidopsis thaliana complex-I (open conformation)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, ...
著者Klusch, N, Kuelbrandt, W.
登録日2020-10-23
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献A ferredoxin bridge connects the two arms of plant mitochondrial complex I.
Plant Cell, 33, 2021
7Z9A
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Sam68
分子名称: 1,2-ETHANEDIOL, Isoform 2 of KH domain-containing, RNA-binding, ...
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-20
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7Z9B
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Sam68
分子名称: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ...
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-20
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.333 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7Z8A
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Sam68
分子名称: 1,2-ETHANEDIOL, KHDR1 protein, LITHIUM ION, ...
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-16
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7Z89
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Sam68
分子名称: 1,2-ETHANEDIOL, IODIDE ION, Isoform 2 of KH domain-containing, ...
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-16
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7ZAC
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Sam68
分子名称: 1,2-ETHANEDIOL, KHDR1 protein, NITRATE ION
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-22
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7ZAB
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Sam68
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Nadal, M, Puestes-Prior, P.
登録日2022-03-22
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7ZAF
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Sam68
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者Nadal, M, Puestes-Prior, P.
登録日2022-03-22
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
7ZAM
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Sam68
分子名称: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ...
著者Nadal, M, Fuentes-Prior, P.
登録日2022-03-22
公開日2023-02-01
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structure and function analysis of Sam68 and hnRNP A1 synergy in the exclusion of exon 7 from SMN2 transcripts.
Protein Sci., 32, 2023
5MF9
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Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
分子名称: RNA-binding protein 5, Survival motor neuron protein
著者Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
登録日2016-11-17
公開日2016-12-07
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
2LEH
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Solution structure of the core SMN-Gemin2 complex
分子名称: Survival motor neuron protein, Survival of motor neuron protein-interacting protein 1
著者Sarachan, K.L, Valentine, K, Gupta, K, Moorman, V, Gledhill, J, Bernens, M, Tommos, C, Wand, A.J, Van Duyne, G.
登録日2011-06-15
公開日2012-06-27
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the core SMN-Gemin2 complex.
Biochem.J., 445, 2012
1MHN
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High resolution crystal structure of the SMN Tudor domain
分子名称: Survival motor neuron protein
著者Sprangers, R, Groves, M.R, Sinning, I, Sattler, M.
登録日2002-08-20
公開日2003-03-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High Resolution X-ray and NMR Structures of the SMN Tudor Domain: conformational variation in the binding site for symmetrically dimethylated arginine residues
J.Mol.Biol., 327, 2003
4GLI
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Crystal Structure of Human SMN YG-Dimer
分子名称: Maltose-binding periplasmic protein, Survival motor neuron protein chimera
著者Martin, R.S, Perry, K, Van Duyne, G.D.
登録日2012-08-14
公開日2012-10-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.903 Å)
主引用文献The survival motor neuron protein forms soluble glycine zipper oligomers.
Structure, 20, 2012
1G5V
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SOLUTION STRUCTURE OF THE TUDOR DOMAIN OF THE HUMAN SMN PROTEIN
分子名称: SURVIVAL MOTOR NEURON PROTEIN 1
著者Selenko, P, Sprangers, R, Stier, G, Buehler, D, Fischer, U, Sattler, M.
登録日2000-11-02
公開日2001-05-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献SMN tudor domain structure and its interaction with the Sm proteins.
Nat.Struct.Biol., 8, 2001

 

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