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4RQX
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Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA
分子名称: 1-THIOETHANESULFONIC ACID, Peroxiredoxin-4
著者Badger, J, Sridhar, V, Logan, C, Hausheer, F.H, Nienaber, V.L.
登録日2014-11-05
公開日2015-04-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.256 Å)
主引用文献Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Molecules, 20, 2015
4FH8
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Crystal Structure of Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum
分子名称: AcePrx-1
著者Nguyen, J.B, Modis, Y.
登録日2012-06-05
公開日2013-06-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Peroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin A.
Chem.Biol., 20, 2013
6UTL
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Yeast Thiol Specific antoxidant 2 with C171S mutation and catalytic cysteine alkylated with iodoacetamide
分子名称: Peroxiredoxin TSA2
著者Tairum, C.A, Bannitz-Fernandes, R, Tonoli, C.C.C, Murakami, M.T, de Oliveira, M.A, Netto, L.E.S.
登録日2019-10-29
公開日2020-07-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Reduction of sulfenic acids by ascorbate in proteins, connecting thiol-dependent to alternative redox pathways.
Free Radic Biol Med, 156, 2020
3EMP
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BU of 3emp by Molmil
Crystal Structure of the S-acetanilide modified form of C165S AhpC
分子名称: Alkyl hydroperoxide reductase subunit C
著者Karplus, P.A, Hall, A.
登録日2008-09-24
公開日2009-03-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Cysteine pK(a) Values for the Bacterial Peroxiredoxin AhpC
Biochemistry, 47, 2008
7LJ1
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BU of 7lj1 by Molmil
Human Prx1-Srx Decameric Complex
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T.
登録日2021-01-28
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State.
Antioxidants (Basel), 10, 2021
3HY2
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Crystal Structure of Sulfiredoxin in Complex with Peroxiredoxin I and ATP:Mg2+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxiredoxin-1, ...
著者Jonsson, T.J, Johnson, L.C, Lowther, W.T.
登録日2009-06-22
公開日2009-10-06
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Protein Engineering of the Quaternary Sulfiredoxin-Peroxiredoxin Enzyme-Substrate Complex Reveals the Molecular Basis for Cysteine Sulfinic Acid Phosphorylation
J.Biol.Chem., 284, 2009
5OVQ
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BU of 5ovq by Molmil
Crystal Structure of the peroxiredoxin (AhpC2) from the Hyperthermophilic bacteria Aquifex aeolicus VF
分子名称: Peroxiredoxin, UNKNOWN LIGAND
著者Warkentin, E, Peng, G.
登録日2017-08-29
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural properties of the peroxiredoxin AhpC2 from the hyperthermophilic eubacterium Aquifex aeolicus.
Biochim Biophys Acta Gen Subj, 1862, 2018
1E2Y
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Tryparedoxin peroxidase from Crithidia fasciculata
分子名称: CHLORIDE ION, TRYPAREDOXIN PEROXIDASE
著者Alphey, M.S, Bond, C.S, Hunter, W.N.
登録日2000-05-30
公開日2001-03-23
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Structure of Reduced Tryparedoxin Peroxidase Reveals a Decamer and Insight Into Reactivity of 2Cys-Peroxiredoxins
J.Mol.Biol., 300, 2000
5JCG
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Structure of Human Peroxiredoxin 3 as three stacked rings
分子名称: Thioredoxin-dependent peroxide reductase, mitochondrial
著者Yewdall, N.A, Gerrard, J.A, Goldstone, D.C.
登録日2016-04-15
公開日2016-05-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Human Peroxiredoxin 3 Suggest Self-Chaperoning Assembly that Maintains Catalytic State.
Structure, 24, 2016
5XBR
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Peroxiredoxin from Pyrococcus horikoshii (sulfonic acid form)
分子名称: GLYCEROL, Peroxiredoxin
著者Nakamura, T, Uegaki, K.
登録日2017-03-21
公開日2018-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Alteration of molecular assembly of peroxiredoxins from hyperthermophilic archaea
J. Biochem., 162, 2017
5XBQ
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Peroxiredoxin from Pyrococcus horikoshii (6m mutant)
分子名称: Peroxiredoxin
著者Nakamura, T, Uegaki, K.
登録日2017-03-21
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Alteration of molecular assembly of peroxiredoxins from hyperthermophilic archaea
J. Biochem., 162, 2017
6P0W
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LsfA from P. aeruginosa, a 1-Cys Prx in reduced form
分子名称: CHLORIDE ION, Putative thiol-specific antioxidant protein
著者AIeixo-Silva, R.L, Domingos, R.M, Netto, L.E.S.
登録日2019-05-17
公開日2020-05-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of LsfA, a 1-Cys Prx in reduced form
To Be Published
5JLY
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BU of 5jly by Molmil
Structure of Peroxiredoxin-1 from Schistosoma japonicum
分子名称: Thioredoxin peroxidase-1
著者Wu, Q, Huang, F, Zeng, D, Liu, X, Zhao, J, Wang, H, Peng, Y, Li, P, Li, Y.
登録日2016-04-27
公開日2017-05-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.051 Å)
主引用文献Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum
To Be Published
6E0G
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BU of 6e0g by Molmil
Mitochondrial peroxiredoxin from Leishmania infantum after heat stress without unfolding client protein
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
6E0F
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Mitochondrial peroxiredoxin from Leishmania infantum in complex with unfolding client protein after heat stress
分子名称: mitochondrial 2-cys-peroxiredoxin
著者Teixeira, F, Tse, E, Makepeace, K.A.T, Borchers, C.H, Castro, H, Tomas, A.M, Poole, L.B, Southworth, D.R, Jakob, U.
登録日2018-07-06
公開日2019-02-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Chaperone activation and client binding of a 2-cysteine peroxiredoxin.
Nat Commun, 10, 2019
5HQP
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BU of 5hqp by Molmil
Crystal structure of the ERp44-peroxiredoxin 4 complex
分子名称: Endoplasmic reticulum resident protein 44, Peroxiredoxin-4
著者Yang, K, Li, D.F, Wang, X, Wang, C.C.
登録日2016-01-22
公開日2016-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention.
Structure, 24, 2016
6Q5V
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BU of 6q5v by Molmil
1-Cys SiPrx, a Prx6-family 1-Cys peroxiredoxin of the thermoacidophilic archaeon Sulfolobus islandicus
分子名称: Peroxiredoxin
著者Stroobants, S, Maes, D, Peeters, E, van Molle, I.
登録日2018-12-09
公開日2019-05-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus.
Acta Crystallogr.,Sect.F, 75, 2019
5EPT
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BU of 5ept by Molmil
Crystal Structure of S. cerevisiae TSA2 in the disulfide state
分子名称: Peroxiredoxin TSA2
著者Nielsen, M.H, Kidmose, R.T, Jenner, L.B.
登録日2015-11-12
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Structure of TSA2 reveals novel features of the active-site loop of peroxiredoxins.
Acta Crystallogr D Struct Biol, 72, 2016
7WEU
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BU of 7weu by Molmil
Crystal structure of Peroxiredoxin I in complex with compound 19-048
分子名称: Peroxiredoxin-1, UNKNOWN LIGAND
著者Zhang, H, Luo, C.
登録日2021-12-24
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
7WET
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Crystal structure of Peroxiredoxin I in complex with the inhibitor Cela
分子名称: (2R,4aS,6aS,12bR,14aS,14bR)-10-hydroxy-2,4a,6a,9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid, Peroxiredoxin-1
著者Zhang, H, Luo, C.
登録日2021-12-24
公開日2022-12-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1.
Signal Transduct Target Ther, 8, 2023
8HH0
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BU of 8hh0 by Molmil
Peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C)
分子名称: 1-naphthalen-2-ylethanone, Peroxiredoxin
著者Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
登録日2022-11-16
公開日2023-03-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
8HLA
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BU of 8hla by Molmil
Heteromeric ring comprised of peroxiredoxin from Thermococcus kodakaraensis (TkPrx) F42C/C46S/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F42C) and TkPrx C46S/F76C/C205S/C211S mutant modified with 2-(bromoacetyl)naphthalene (Naph@TkPrx*F76C) (Naph@(MIX|3:3))
分子名称: 1-naphthalen-2-ylethanone, Peroxiredoxin
著者Himiyama, T, Hamaguchi, T, Yonekura, K, Nakamura, T.
登録日2022-11-29
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Unnaturally Distorted Hexagonal Protein Ring Alternatingly Reorganized from Two Distinct Chemically Modified Proteins.
Bioconjug.Chem., 2023
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
分子名称: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EKW
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Cryo-EM structure of human PRDX4
分子名称: Peroxiredoxin-4
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
5DVB
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Crystal Structure of S. cerevisiae TSA2
分子名称: Tsa2p
著者Nielsen, M.H, Kidmose, R.T, Jenner, L.B.
登録日2015-09-21
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of TSA2 reveals novel features of the active-site loop of peroxiredoxins.
Acta Crystallogr D Struct Biol, 72, 2016

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