PDB: 12 件ウェブページステータス検索Chemie searchBIRD

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1KS6	Transforming Growth Factor Beta type II receptor ligand binding domain 分子名称: TRANSFORMING GROWTH FACTOR BETA TYPE II RECEPTOR 著者 Marlow, M.S, Brown, C.B, Barnett, J.V, Krezel, A.M. 登録日 2002-01-10 公開日 2003-02-25 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of the chick TGFb type II receptor ligand binding domain J.Mol.Biol., 326, 2003
1KTZ	Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3 分子名称: TGF-beta Type II Receptor, TRANSFORMING GROWTH FACTOR BETA 3 著者 Hart, P.J, Deep, S, Taylor, A.B, Shu, Z, Hinck, C.S, Hinck, A.P. 登録日 2002-01-18 公開日 2002-02-27 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex. Nat.Struct.Biol., 9, 2002
1M9Z	CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN 分子名称: GLYCEROL, TGF-BETA RECEPTOR TYPE II 著者 Boesen, C.C, Radaev, S, Motyka, S.A, Patamawenu, A, Sun, P.D. 登録日 2002-07-30 公開日 2002-09-11 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 THE 1.1A CRYSTAL STRUCTURE OF HUMAN TGF-BETA TYPE II RECEPTOR LIGAND BINDING DOMAIN Structure, 10, 2002
1PLO	TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR EXTRACELLULAR DOMAIN 分子名称: TGF-beta receptor type II 著者 Deep, S, Walker III, K.P, Shu, Z, Hinck, A.P. 登録日 2003-06-08 公開日 2003-09-23 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of the TGF-beta type II receptor extracellular domain Biochemistry, 42, 2003
2PJY	Structural basis for cooperative assembly of the TGF-beta signaling complex 分子名称: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-3 著者 Groppe, J, Zubieta, C. 登録日 2007-04-16 公開日 2008-02-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding. Mol.Cell, 29, 2008
3KFD	Ternary complex of TGF-b1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily 分子名称: TGF-beta receptor type-1, TGF-beta receptor type-2, Transforming growth factor beta-1 著者 Radaev, S, Sun, P.D. 登録日 2009-10-27 公開日 2010-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.995 Å) 主引用文献 Ternary complex of transforming growth factor-beta1 reveals isoform-specific ligand recognition and receptor recruitment in the superfamily. J.Biol.Chem., 285, 2010
4P7U	Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with NDSB-201 分子名称: 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, TGF-beta receptor type-2 著者 Wangkanont, K, Forest, K.T. 登録日 2014-03-27 公開日 2015-06-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.502 Å) 主引用文献 The non-detergent sulfobetaine-201 acts as a pharmacological chaperone to promote folding and crystallization of the type II TGF-beta receptor extracellular domain. Protein Expr.Purif., 115, 2015
4XJJ	Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201 分子名称: 3-[2-(2-hydroxyethyl)pyridinium-1-yl]propane-1-sulfonate, TGF-beta receptor type-2 著者 Wangkanont, K, Forest, K.T, Kiessling, L.L. 登録日 2015-01-08 公開日 2015-06-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Extracellular domain of type II Transforming Growth Factor Beta receptor in complex with 2-(2-Hydroxyethyl)NDSB-201 to be published
5TX4	Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130 分子名称: TGF-beta receptor type-2, Transforming growth factor beta-2 著者 Hinck, A.P, Kim, S. 登録日 2016-11-15 公開日 2017-03-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.876 Å) 主引用文献 An engineered transforming growth factor beta (TGF-beta ) monomer that functions as a dominant negative to block TGF-beta signaling. J. Biol. Chem., 292, 2017
5TY4	MicroED structure of a complex between monomeric TGF-b and its receptor, TbRII, at 2.9 A resolution 分子名称: TGF-beta receptor type-2, mmTGF-b2-7m 著者 Weiss, S.C, de la Cruz, M.J, Hattne, J, Shi, D, Reyes, F.E, Callero, G, Gonen, T. 登録日 2016-11-18 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 ELECTRON CRYSTALLOGRAPHY (2.9 Å) 主引用文献 Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
8G4K	Complex of TbRII mini protein binder bound to the TbRII ECD 分子名称: 5HCS_TGFBR2_1, SULFATE ION, TGF-beta receptor type-2 著者 Schwartze, T.S, Hinck, A.P. 登録日 2023-02-09 公開日 2024-08-14 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Computational Design of High Affinity Binders to Convex Protein Target Sites To be Published
8GDT	Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain 分子名称: CACODYLATE ION, CHLORIDE ION, GLYCEROL, ... 著者 White, S.E, Schwartze, T.A, Hinck, A.P. 登録日 2023-03-06 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.401 Å) 主引用文献 Heligmosomoides polygyrus TGF-beta Mimic 6 Domain 3 (TGM6-D3) Bound to Human TGF-beta Type II Receptor Extracellular Domain To Be Published