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8DCM
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BU of 8dcm by Molmil
Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-06-16
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin.
J.Bacteriol., 205, 2023
7YVS
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BU of 7yvs by Molmil
Complex structure of Clostridioides difficile binary toxin unfolded CDTa-bound CDTb-pore (short).
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2022-08-19
公開日2022-10-26
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7YVQ
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BU of 7yvq by Molmil
Complex structure of Clostridioides difficile binary toxin folded CDTa-bound CDTb-pore (short).
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosylating binary toxin enzymatic subunit CdtA, CALCIUM ION
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2022-08-19
公開日2022-10-26
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7VNN
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BU of 7vnn by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with long stem
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, CALCIUM ION, CdtA
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2021-10-11
公開日2022-10-26
最終更新日2022-11-02
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7VNJ
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BU of 7vnj by Molmil
Complex structure of Clostridioides difficile enzymatic component (CDTa) and binding component (CDTb) pore with short stem
分子名称: ADP-ribosylating binary toxin binding subunit CdtB, ADP-ribosyltransferase enzymatic component, CALCIUM ION
著者Yamada, T, Kawamoto, A, Yoshida, T, Sato, Y, Kato, T, Tsuge, H.
登録日2021-10-11
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Cryo-EM structures of the translocational binary toxin complex CDTa-bound CDTb-pore from Clostridioides difficile.
Nat Commun, 13, 2022
7O85
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BU of 7o85 by Molmil
Anthrax toxin prepore in complex with the neutralizing Fab cAb29
分子名称: CALCIUM ION, Fab, Protective antigen PA-63
著者Hoelzgen, F, Zalk, R, Alcalay, R, Cohen-Schwartz, S, Garau, G, Shahar, A, Mazor, O, Frank, G.A.
登録日2021-04-14
公開日2021-04-28
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Neutralization of the anthrax toxin by antibody-mediated stapling of its membrane-penetrating loop.
Acta Crystallogr D Struct Biol, 77, 2021
7MJR
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BU of 7mjr by Molmil
Vip4Da2 toxin structure
分子名称: CALCIUM ION, SULFATE ION, Vip4Da1 protein
著者Rydel, T.J, Duda, D, Zheng, M, Henry, A.
登録日2021-04-20
公開日2021-05-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Plos One, 16, 2021
7KXR
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BU of 7kxr by Molmil
Protective antigen pore translocating lethal factor N-terminal domain
分子名称: CALCIUM ION, Lethal factor, Protective antigen
著者Machen, A.J, Freudenthal, B.D.
登録日2020-12-04
公開日2021-07-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Anthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism.
Sci Rep, 11, 2021
6ZXL
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BU of 6zxl by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1A) arrangement
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXK
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BU of 6zxk by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state and PA7LF(2+1B) arrangement
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6ZXJ
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BU of 6zxj by Molmil
Fully-loaded anthrax lethal toxin in its heptameric pre-pore state, in which the third lethal factor is masked out (PA7LF3-masked)
分子名称: Lethal factor, Protective antigen
著者Quentin, D, Antoni, C, Gatsogiannis, C, Raunser, S.
登録日2020-07-29
公開日2020-09-02
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the fully-loaded asymmetric anthrax lethal toxin in its heptameric pre-pore state.
Plos Pathog., 16, 2020
6WJJ
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BU of 6wjj by Molmil
Anthrax octamer prechannel bound to full-length lethal factor
分子名称: CALCIUM ION, Lethal factor, Protective antigen, ...
著者Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H.
登録日2020-04-13
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
6VRA
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BU of 6vra by Molmil
Anthrax octamer prechannel bound to full-length edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Zhou, K, Hardenbrook, N.J, Liu, S, Cui, Y.X, Krantz, B.A, Zhou, Z.H.
登録日2020-02-07
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Atomic Structures of Anthrax Prechannel Bound with Full-Length Lethal and Edema Factors.
Structure, 28, 2020
6V1S
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BU of 6v1s by Molmil
Structure of the Clostridioides difficile transferase toxin
分子名称: ADP-ribosylating binary toxin enzymatic subunit CdtA, ADP-ribosyltransferase binding component, CALCIUM ION
著者Sheedlo, M.J, Anderson, D.M, Thomas, A.K, Lacy, D.B.
登録日2019-11-21
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural elucidation of theClostridioides difficiletransferase toxin reveals a single-site binding mode for the enzyme.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UZE
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BU of 6uze by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-15
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6UZD
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BU of 6uzd by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-14
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6UZB
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BU of 6uzb by Molmil
Anthrax toxin protective antigen channels bound to edema factor
分子名称: CALCIUM ION, Calmodulin-sensitive adenylate cyclase, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-11-14
公開日2020-03-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6UWT
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BU of 6uwt by Molmil
Clostridium difficile binary toxin translocase CDTb tetradecamer in symmetric conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UWR
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BU of 6uwr by Molmil
Clostridium difficile binary toxin translocase CDTb in asymmetric tetradecamer conformation
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Xu, X, Pozharski, E, des Georges, A.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UWI
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BU of 6uwi by Molmil
Crystal structure of the Clostridium difficile translocase CDTb
分子名称: ADP-ribosyltransferase binding component, CALCIUM ION
著者Pozharski, E.
登録日2019-11-05
公開日2020-01-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of the cell-binding component of theClostridium difficilebinary toxin reveals a di-heptamer macromolecular assembly.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UJI
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BU of 6uji by Molmil
Low resolution crystal structure (5.5 A) of the anthrax toxin protective antigen heptamer prepore D425A mutant
分子名称: Protective antigen PA-63
著者Lovell, S, Mehzabeen, N, Battaile, K.P, Bann, J.G.
登録日2019-10-03
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structure of the anthrax protective antigen D425A dominant negative mutant reveals a stalled intermediate state of pore maturation.
J.Mol.Biol., 2022
6PSN
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BU of 6psn by Molmil
Anthrax toxin protective antigen channels bound to lethal factor
分子名称: CALCIUM ION, Lethal factor, Protective antigen
著者Hardenbrook, N.J, Liu, S, Zhou, K, Zhou, Z.H, Krantz, B.A.
登録日2019-07-12
公開日2020-03-04
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors.
Nat Commun, 11, 2020
6OKU
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BU of 6oku by Molmil
CDTb Double Heptamer Long Form Mask 3 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry
分子名称: ADP-ribosyltransferase binding component
著者Lacy, D.B, Sheedlo, M.J, Anderson, D.M.
登録日2019-04-15
公開日2019-10-30
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
Nat Microbiol, 5, 2020
6OKT
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BU of 6okt by Molmil
CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry
分子名称: ADP-ribosyltransferase binding component
著者Lacy, D.B, Sheedlo, M.J, Anderson, D.M.
登録日2019-04-15
公開日2019-10-30
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
Nat Microbiol, 5, 2020
6OKS
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BU of 6oks by Molmil
CDTb Double Heptamer Long Form Mask 1 Modeled from Cryo-EM Map Reconstructed using C7 Symmetry
分子名称: ADP-ribosyltransferase binding component
著者Lacy, D.B, Sheedlo, M.J, Anderson, D.M.
登録日2019-04-15
公開日2019-10-30
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
Nat Microbiol, 5, 2020

 

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