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1B3U
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CRYSTAL STRUCTURE OF CONSTANT REGULATORY DOMAIN OF HUMAN PP2A, PR65ALPHA
分子名称: PROTEIN (PROTEIN PHOSPHATASE PP2A)
著者Groves, M.R, Hanlon, N, Turowski, P, Hemmings, B, Barford, D.
登録日1998-12-14
公開日1999-04-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of the protein phosphatase 2A PR65/A subunit reveals the conformation of its 15 tandemly repeated HEAT motifs.
Cell(Cambridge,Mass.), 96, 1999
1QBK
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STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX
分子名称: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
著者Chook, Y.M, Blobel, G.
登録日1999-04-23
公開日1999-06-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp.
Nature, 399, 1999
2BKU
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Kap95p:RanGTP complex
分子名称: GTP-BINDING NUCLEAR PROTEIN RAN, GUANOSINE-5'-TRIPHOSPHATE, IMPORTIN BETA-1 SUBUNIT, ...
著者Lee, S.J, Matsuura, Y, Liu, S.M, Stewart, M.
登録日2005-02-21
公開日2005-05-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Basis for Nuclear Import Complex Dissociation by Rangtp
Nature, 435, 2005
2DB0
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Crystal structure of PH0542
分子名称: 253aa long hypothetical protein
著者Nishino, A, Handa, N, Kishishita, S, Murayama, K, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-14
公開日2006-06-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of PH0542
To be Published
2H4M
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Karyopherin Beta2/Transportin-M9NLS
分子名称: Heterogeneous nuclear ribonucleoprotein A1, Transportin-1
著者Chook, Y.M, Cansizoglu, A.E.
登録日2006-05-24
公開日2006-10-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Rules for nuclear localization sequence recognition by karyopherin beta 2.
Cell(Cambridge,Mass.), 126, 2006
2IAE
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Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme.
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
著者Cho, U.S, Xu, W.
登録日2006-09-07
公開日2006-12-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
Nature, 445, 2007
2IE3
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Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins
分子名称: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ...
著者Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
2IE4
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Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid
分子名称: MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ...
著者Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y.
登録日2006-09-17
公開日2006-11-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins
Cell(Cambridge,Mass.), 127, 2006
2NPP
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Structure of the Protein Phosphatase 2A Holoenzyme
分子名称: MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ...
著者Xu, Y, Chen, Y, Xing, Y, Chao, Y, Shi, Y.
登録日2006-10-28
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the protein phosphatase 2A holoenzyme
Cell(Cambridge,Mass.), 127, 2006
2NYL
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Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl terminus truncated
分子名称: MANGANESE (II) ION, Protein phosphatase 2, regulatory subunit A (PR 65), ...
著者Xing, Y, Xu, Y, Chen, Y, Chao, Y, Lin, Z, Shi, Y.
登録日2006-11-20
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
2NYM
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Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit
分子名称: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
著者Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y.
登録日2006-11-21
公開日2006-12-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure of the Protein Phosphatase 2A Holoenzyme.
Cell(Cambridge,Mass.), 127, 2006
2OT8
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Karyopherin Beta2/Transportin-hnRNPM NLS Complex
分子名称: Heterogeneous nuclear ribonucleoprotein M, Transportin-1
著者Cansizoglu, A.E, Chook, Y.M.
登録日2007-02-07
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-based design of a pathway-specific nuclear import inhibitor.
Nat.Struct.Mol.Biol., 14, 2007
2PF4
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BU of 2pf4 by Molmil
Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit
分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION
著者Cho, U, Morrone, S, Xu, W.
登録日2007-04-03
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of PP2A inhibition by small t antigen.
Plos Biol., 5, 2007
2PKG
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Structure of a complex between the A subunit of protein phosphatase 2A and the small t antigen of SV40
分子名称: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION
著者Jeffrey, P.D, Shi, Y.
登録日2007-04-17
公開日2007-05-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.
Nat.Struct.Mol.Biol., 14, 2007
2QMR
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Karyopherin beta2/transportin
分子名称: Transportin-1
著者Cansizoglu, A.E, Chook, Y.M.
登録日2007-07-16
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational heterogeneity of karyopherin beta2 is segmental
Structure, 15, 2007
2Z5J
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BU of 2z5j by Molmil
Free Transportin 1
分子名称: Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
登録日2007-07-13
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5K
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Complex of Transportin 1 with TAP NLS
分子名称: Nuclear RNA export factor 1, PHOSPHATE ION, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Kose, S, Imamoto, N, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5M
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Complex of Transportin 1 with TAP NLS, crystal form 2
分子名称: Nuclear RNA export factor 1, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5N
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Complex of Transportin 1 with hnRNP D NLS
分子名称: Heterogeneous nuclear ribonucleoprotein D0, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
2Z5O
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BU of 2z5o by Molmil
Complex of Transportin 1 with JKTBP NLS
分子名称: Heterogeneous nuclear ribonucleoprotein D-like, Transportin-1
著者Imasaki, T, Shimizu, T, Hashimoto, H, Hidaka, Y, Kose, S, Imamoto, N, Yamada, M, Sato, M.
登録日2007-07-14
公開日2007-10-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for substrate recognition and dissociation by human transportin 1
Mol.Cell, 28, 2007
3C5W
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BU of 3c5w by Molmil
Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme
分子名称: PP2A A subunit, PP2A C subunit, PP2A-specific methylesterase PME-1
著者Xing, Y, Li, Z, Chen, Y, Stock, J, Jeffrey, P.D, Shi, Y.
登録日2008-02-01
公開日2008-04-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanism of demethylation and inactivation of protein phosphatase 2A.
Cell(Cambridge,Mass.), 133, 2008
3DW8
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Structure of a Protein Phosphatase 2A Holoenzyme with B55 subunit
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, ...
著者Xu, Y, Chen, Y, Zhang, P, Jeffrey, P.D, Shi, Y.
登録日2008-07-21
公開日2008-10-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation.
Mol.Cell, 31, 2008
3EA5
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Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
著者Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
登録日2008-08-24
公開日2008-10-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
3FGA
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Structural Basis of PP2A and Sgo interaction
分子名称: MANGANESE (II) ION, MICROCYSTIN-LR, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ...
著者Xu, Z, Xu, W.
登録日2008-12-05
公開日2009-09-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and function of the PP2A-shugoshin interaction
Mol.Cell, 35, 2009
3K7V
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Protein phosphatase 2A core complex bound to dinophysistoxin-1
分子名称: (2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-6'-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-1-hydroxybutyl}-8'-hydroxy-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid, MANGANESE (II) ION, SULFATE ION, ...
著者Jeffrey, P.D, Huhn, J, Shi, Y.
登録日2009-10-13
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A structural basis for the reduced toxicity of dinophysistoxin-2.
Chem.Res.Toxicol., 22, 2009

 

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