7MIX
| Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Gao, S, Yao, X. | 登録日 | 2021-04-18 | 公開日 | 2021-07-07 | 最終更新日 | 2021-08-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of human Ca v 2.2 channel blocked by the painkiller ziconotide. Nature, 596, 2021
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7VFU
| Human N-type voltage gated calcium channel CaV2.2-alpha2/delta1-beta1 complex, bound to ziconotide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Dong, Y, Gao, Y, Wang, Y, Zhao, Y. | 登録日 | 2021-09-13 | 公開日 | 2021-11-03 | 最終更新日 | 2022-02-16 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Closed-state inactivation and pore-blocker modulation mechanisms of human Ca V 2.2. Cell Rep, 37, 2021
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1OMC
| SOLUTION STRUCTURE OF OMEGA-CONOTOXIN GVIA USING 2-D NMR SPECTROSCOPY AND RELAXATION MATRIX ANALYSIS | 分子名称: | OMEGA-CONOTOXIN GVIA | 著者 | Davis, J.H, Bradley, E.K, Miljanich, G.P, Nadasdi, L, Ramachandran, J, Basus, V.J. | 登録日 | 1993-04-28 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of omega-conotoxin GVIA using 2-D NMR spectroscopy and relaxation matrix analysis. Biochemistry, 32, 1993
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2N8H
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2N8E
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1TTL
| Omega-conotoxin GVIA, a N-type calcium channel blocker | 分子名称: | Omega-conotoxin GVIA | 著者 | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | 登録日 | 2004-06-23 | 公開日 | 2004-07-13 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels J.Biol.Chem., 279, 2004
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1F3K
| THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER | 分子名称: | OMEGA-CONOTOXIN TXVII | 著者 | Kobayashi, K, Sasaki, T, Sato, K, Kohno, T. | 登録日 | 2000-06-05 | 公開日 | 2000-12-13 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker. Biochemistry, 39, 2000
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1TTK
| NMR solution structure of omega-conotoxin MVIIA, a N-type calcium channel blocker | 分子名称: | Omega-conotoxin MVIIa | 著者 | Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J. | 登録日 | 2004-06-22 | 公開日 | 2004-07-06 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals J.Biol.Chem., 278, 2003
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1TR6
| NMR solution structure of omega-conotoxin [K10]GVIA, a cyclic cysteine knot peptide | 分子名称: | Omega-conotoxin GVIA | 著者 | Mould, J, Yasuda, T, Schroeder, C.I, Beedle, A.M, Doering, C.J, Zamponi, G.W, Adams, D.J, Lewis, R.J. | 登録日 | 2004-06-21 | 公開日 | 2004-07-13 | 最終更新日 | 2011-10-05 | 実験手法 | SOLUTION NMR | 主引用文献 | The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels J.Biol.Chem., 279, 2004
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1TT3
| NMR soulution structure of omega-conotoxin [K10]MVIIA | 分子名称: | Omega-conotoxin MVIIa | 著者 | Adams, D.J, Smith, A.B, Schroeder, C.I, Yasuda, T, Lewis, R.J. | 登録日 | 2004-06-21 | 公開日 | 2004-07-06 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | omega-conotoxin CVID inhibits a pharmacologically distinct voltage-sensitive calcium channel associated with transmitter release from preganglionic nerve terminals J.Biol.Chem., 278, 2003
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1OMG
| NMR STUDY OF OMEGA-CONOTOXIN MVIIA | 分子名称: | OMEGA-CONOTOXIN MVIIA | 著者 | Kohno, T, Kim, J.-I, Kobayashi, K, Kodera, Y, Maeda, T, Sato, K. | 登録日 | 1995-04-26 | 公開日 | 1996-04-03 | 最終更新日 | 2024-10-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin MVIIA. Biochemistry, 34, 1995
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1DW4
| NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: CONSTRAINTS ON DISULPHIDE BRIDGES | 分子名称: | OMEGA-CONOTOXIN MVIIA | 著者 | Atkinson, R.A, Kieffer, B, Dejaegere, A, Sirockin, F, Lefevre, J.-F. | 登録日 | 2000-01-24 | 公開日 | 2000-03-01 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange. Biochemistry, 39, 2000
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1DW5
| NMR STRUCTURE OF OMEGA-CONOTOXIN MVIIA: NO CONSTRAINTS ON DISULPHIDE BRIDGES | 分子名称: | OMEGA-CONOTOXIN MVIIA | 著者 | Atkinson, R.A, Kieffer, B, Dejaegere, A, Sirockin, F, Lefevre, J.-F. | 登録日 | 2000-01-24 | 公開日 | 2000-03-01 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and dynamic characterization of omega-conotoxin MVIIA: the binding loop exhibits slow conformational exchange. Biochemistry, 39, 2000
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2CCO
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1FEO
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1FYG
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1JLO
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1MVI
| N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA, NMR, 15 STRUCTURES | 分子名称: | MVIIA | 著者 | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | 登録日 | 1996-08-02 | 公開日 | 1997-08-12 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. J.Mol.Biol., 263, 1996
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1MVJ
| N-TYPE CALCIUM CHANNEL BLOCKER, OMEGA-CONOTOXIN MVIIA NMR, 15 STRUCTURES | 分子名称: | SVIB | 著者 | Nielsen, K.J, Thomas, L, Lewis, R.J, Alewood, P.F, Craik, D.J. | 登録日 | 1996-08-02 | 公開日 | 1997-08-12 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A consensus structure for omega-conotoxins with different selectivities for voltage-sensitive calcium channel subtypes: comparison of MVIIA, SVIB and SNX-202. J.Mol.Biol., 263, 1996
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1FU3
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2LOC
| Conotoxin analogue [D-Ala2]BuIIIB | 分子名称: | Mu-conotoxin BuIIIB | 著者 | Kuang, Z. | 登録日 | 2012-01-21 | 公開日 | 2013-01-23 | 最終更新日 | 2024-10-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency. Acs Chem.Biol., 8, 2013
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1AS5
| SOLUTION STRUCTURE OF CONOTOXIN Y-PIIIE FROM CONUS PURPURASCENS, NMR, 14 STRUCTURES | 分子名称: | CONOTOXIN Y-PIIIE | 著者 | Mitchell, S.S, Shon, K, Foster, M.P, Olivera, B.M, Ireland, C.M. | 登録日 | 1997-08-13 | 公開日 | 1998-10-14 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist. Biochemistry, 37, 1998
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1AV3
| POTASSIUM CHANNEL BLOCKER KAPPA CONOTOXIN PVIIA FROM C. PURPURASCENS, NMR, 20 STRUCTURES | 分子名称: | Kappa-conotoxin PVIIA | 著者 | Scanlon, M.J, Naranjo, D, Thomas, L, Alewood, P.F, Lewis, R.J, Craik, D.J. | 登録日 | 1997-09-24 | 公開日 | 1998-10-14 | 最終更新日 | 2020-12-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and proposed binding mechanism of a novel potassium channel toxin kappa-conotoxin PVIIA. Structure, 5, 1997
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1KCP
| 3D STRUCTURE OF K-CONOTOXIN PVIIA, A NOVEL POTASSIUM CHANNEL-BLOCKING TOXIN FROM CONE SNAILS, NMR, 22 STRUCTURES | 分子名称: | KAPPA-CONOTOXIN PVIIA | 著者 | Savarin, P, Guenneugues, M, Gilquin, B, Lamthanh, H, Gasparini, S, Zinn-Justin, S, Menez, A. | 登録日 | 1998-01-27 | 公開日 | 1998-10-14 | 最終更新日 | 2017-11-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional structure of kappa-conotoxin PVIIA, a novel potassium channel-blocking toxin from cone snails. Biochemistry, 37, 1998
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2LO9
| NMR solution structure of Mu-contoxin BuIIIB | 分子名称: | Mu-conotoxin BuIIIB | 著者 | Kuang, Z. | 登録日 | 2012-01-20 | 公開日 | 2013-01-23 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Mammalian neuronal sodium channel blocker mu-conotoxin BuIIIB has a structured N-terminus that influences potency. Acs Chem.Biol., 8, 2013
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