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8DNM
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Human Brain Dihydropyrimidinase-related protein 2
分子名称: Dihydropyrimidinase-related protein 2
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
5VGM
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Crystal structure of dihydroorotase pyrC from Vibrio cholerae in complex with zinc at 1.95 A resolution.
分子名称: ACETATE ION, CHLORIDE ION, Dihydroorotase, ...
著者Lipowska, J, Shabalin, I.G, Miks, C.D, Winsor, J, Cooper, D.R, Shuvalova, L, Kwon, K, Lewinski, K, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-04-11
公開日2017-04-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
4V1Y
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The structure of the hexameric atrazine chlorohydrolase, AtzA
分子名称: 1,2-ETHANEDIOL, ATRAZINE CHLOROHYDROLASE, CHLORIDE ION, ...
著者Peat, T.S, Newman, J, Balotra, S, Lucent, D, Warden, A.C, Scott, C.
登録日2014-10-04
公開日2015-03-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Hexameric Atrazine Chlorohydrolase Atza.
Acta Crystallogr.,Sect.D, 71, 2015
7E3U
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BU of 7e3u by Molmil
Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-AU
分子名称: 5-AMINO-1H-PYRIMIDINE-2,4-DIONE, D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Yang, Y.C, Luo, R.H, Huang, Y.H, Huang, C.Y, Lin, E.S.
登録日2021-02-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.159 Å)
主引用文献Molecular Insights into How the Dimetal Center in Dihydropyrimidinase Can Bind the Thymine Antagonist 5-Aminouracil: A Different Binding Mode from the Anticancer Drug 5-Fluorouracil.
Bioinorg Chem Appl, 2022, 2022
8WQ9
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Crystal structure of dihydropyrimidinase complexed with gamma-aminobutyric acid
分子名称: D-hydantoinase/dihydropyrimidinase, GAMMA-AMINO-BUTANOIC ACID, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2023-10-11
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The complexed crystal structure of dihydropyrimidinase reveals a potential interactive link with the neurotransmitter gamma-aminobutyric acid (GABA).
Biochem.Biophys.Res.Commun., 692, 2024
5UQC
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BU of 5uqc by Molmil
Crystal structure of mouse CRMP2
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Dihydropyrimidinase-related protein 2
著者Khanna, M, Khanna, R, Perez-Miller, S, Francois-Moutal, L.
登録日2017-02-07
公開日2017-03-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function.
Channels (Austin), 11, 2017
6JV9
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Crystal Structure of Human CRMP2 1-532, unmodified
分子名称: 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Dihydropyrimidinase-related protein 2, ...
著者Jiang, X, Ogawa, T, Hirokawa, N.
登録日2019-04-16
公開日2019-10-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Enhanced carbonyl stress induces irreversible multimerization of CRMP2 in schizophrenia pathogenesis.
Life Sci Alliance, 2, 2019
2FVM
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Crystal structure of dihydropyrimidinase from Saccharomyces kluyveri in complex with the reaction product N-carbamyl-beta-alanine
分子名称: N-(AMINOCARBONYL)-BETA-ALANINE, ZINC ION, dihydropyrimidinase
著者Dobritzsch, D, Lohkamp, B.
登録日2006-01-31
公開日2006-03-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The Crystal Structures of Dihydropyrimidinases Reaffirm the Close Relationship between Cyclic Amidohydrolases and Explain Their Substrate Specificity.
J.Biol.Chem., 281, 2006
2G3F
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BU of 2g3f by Molmil
Crystal Structure of imidazolonepropionase complexed with imidazole-4-acetic acid sodium salt, a substrate homologue
分子名称: 2H-IMIDAZOL-4-YLACETIC ACID, Imidazolonepropionase, ZINC ION
著者Yu, Y, Liang, Y.H, Su, X.D.
登録日2006-02-19
公開日2006-09-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis
J.Biol.Chem., 281, 2006
6KLK
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BU of 6klk by Molmil
Crystal structure of the Pseudomonas aeruginosa dihydropyrimidinase complexed with 5-FU
分子名称: 5-FLUOROURACIL, D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Chen, I.C, Huang, C.Y.
登録日2019-07-30
公開日2019-11-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.759 Å)
主引用文献Crystal structure of dihydropyrimidinase in complex with anticancer drug 5-fluorouracil.
Biochem.Biophys.Res.Commun., 519, 2019
4UB9
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BU of 4ub9 by Molmil
Structural and catalytic characterization of molinate hydrolase
分子名称: Molinate hydrolase, ZINC ION
著者Leite, J.P, Duarte, M, Paiva, A, Ferreira-da-Silva, F, Matias, P.M, Nunes, O, Gales, L.
登録日2014-08-12
公開日2015-06-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structure-guided engineering of molinate hydrolase for the degradation of thiocarbamate pesticides.
Plos One, 10, 2015
6AJD
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BU of 6ajd by Molmil
Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-27
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun., 505, 2018
7NUU
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BU of 7nuu by Molmil
Crystal structure of human AMDHD2 in complex with Zn
分子名称: GLYCEROL, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S.
登録日2021-03-14
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.836 Å)
主引用文献GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.
Elife, 11, 2022
7NUT
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Crystal structure of human AMDHD2 in complex with Zn and GlcN6P
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION
著者Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S.
登録日2021-03-14
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway.
Elife, 11, 2022
6CTY
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BU of 6cty by Molmil
Crystal structure of dihydroorotase pyrC from Yersinia pestis in complex with zinc and malate at 2.4 A resolution
分子名称: D-MALATE, Dihydroorotase, ZINC ION
著者Lipowska, J, Shabalin, I.G, Winsor, J, Woinska, M, Cooper, D.R, Kwon, K, Shuvalova, L, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-03-23
公開日2018-04-04
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae.
Int.J.Biol.Macromol., 136, 2019
7U5K
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Cryo-EM Structure of DPYSL2
分子名称: Dihydropyrimidinase-related protein 2
著者Morgan, C.E, Yu, E.W.
登録日2022-03-02
公開日2022-12-14
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Toward structural-omics of the bovine retinal pigment epithelium.
Cell Rep, 41, 2022
5HME
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BU of 5hme by Molmil
Crystal structure of Triazine Hydrolase variant (P214T/Y215H)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.151 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
5E5C
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BU of 5e5c by Molmil
Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, C.C, Huang, Y.H, Hsieh, Y.C, Tzeng, C.T, Chen, C.J, Huang, C.Y.
登録日2015-10-08
公開日2016-09-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of dihydropyrimidinase from Pseudomonas aeruginosa PAO1: Insights into the molecular basis of formation of a dimer
Biochem.Biophys.Res.Commun., 478, 2016
3HM7
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BU of 3hm7 by Molmil
Crystal structure of allantoinase from Bacillus halodurans C-125
分子名称: Allantoinase, ZINC ION
著者Patskovsky, Y, Romero, R, Rutter, M, Miller, S, Wasserman, S.R, Sauder, J.M, Raushel, F.M, Burley, S.K, Almo, S.C, New York Structural GenomiX Research Consortium (NYSGXRC), New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2009-05-28
公開日2009-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of Allantoinase from Bacillus Halodurans
To be Published
3IV8
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BU of 3iv8 by Molmil
N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate
分子名称: 6-O-phosphono-beta-D-fructofuranose, N-acetylglucosamine-6-phosphate deacetylase, NICKEL (II) ION, ...
著者Osipiuk, J, Maltseva, N, Stam, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-08-31
公開日2009-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献X-ray crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate.
To be Published
5HMD
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BU of 5hmd by Molmil
Crystal structure of triazine hydrolase variant (Y215H/E241Q)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
7UOF
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BU of 7uof by Molmil
Dihydroorotase from M. jannaschii
分子名称: Dihydroorotase, ZINC ION
著者Vitali, J, Nix, J.C, Newman, H.E, Colaneri, M.J.
登録日2022-04-12
公開日2022-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of Methanococcus jannaschii dihydroorotase.
Proteins, 91, 2023
7X68
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CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone
分子名称: (3aR,5S,8R,8aR,9aR)-5,8a-dimethyl-3-methylidene-8-oxidanyl-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one, Dihydropyrimidinase-related protein 2, SODIUM ION
著者Zhang, S.D, Ma, Y.F, Zhang, J.
登録日2022-03-06
公開日2022-05-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献CYS179 and CYS504 of CRMP2 were covalently binded by a Sesquiterpene lactone
To Be Published
5HMF
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BU of 5hmf by Molmil
Crystal structure of triazine hydrolase variant (P214T/Y215H/E241Q)
分子名称: Triazine hydrolase, ZINC ION
著者Sugrue, E, Carr, P.D, Jackson, C.J.
登録日2016-01-16
公開日2016-11-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Active Site Desolvation and Thermostability Trade-Offs in the Evolution of Catalytically Diverse Triazine Hydrolases.
Biochemistry, 55, 2016
3JZE
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1.8 Angstrom resolution crystal structure of dihydroorotase (pyrC) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
分子名称: ACETIC ACID, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
著者Minasov, G, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-09-23
公開日2009-09-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献1.8 Angstrom Resolution Crystal Structure of Dihydroorotase (pyrC) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2.
TO BE PUBLISHED

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件を2024-07-10に公開中

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