2IC8
 
 | | Crystal structure of GlpG | | 分子名称: | Protein glpG, nonyl beta-D-glucopyranoside | | 著者 | Ha, Y. | | 登録日 | 2006-09-12 | | 公開日 | 2006-10-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of a rhomboid family intramembrane protease.
Nature, 444, 2006
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2IRV
 | | Crystal structure of GlpG, a rhomboid intramembrane serine protease | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, DODECYL-BETA-D-MALTOSIDE, LAURYL DIMETHYLAMINE-N-OXIDE, ... | | 著者 | Bibi, E, Fass, D, Ben-Shem, A. | | 登録日 | 2006-10-16 | | 公開日 | 2006-10-31 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for intramembrane proteolysis by rhomboid serine proteases.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2NR9
 | | Crystal structure of GlpG, Rhomboid Peptidase from Haemophilus influenzae | | 分子名称: | (R)-2-(FORMYLOXY)-3-(PHOSPHONOOXY)PROPYL PENTANOATE, 3,6,12,15,18,21,24-HEPTAOXAHEXATRIACONTAN-1-OL, Protein glpG homolog | | 著者 | Lemieux, M.J, Fischer, S.J, Cherney, M.M, Bateman, K.S, James, M.N.G. | | 登録日 | 2006-11-01 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The crystal structure of the rhomboid peptidase from Haemophilus influenzae provides insight into intramembrane proteolysis.
Proc.Natl.Acad.Sci.USA, 104, 2007
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2NRF
 | | Crystal Structure of GlpG, a Rhomboid family intramembrane protease | | 分子名称: | Protein GlpG | | 著者 | Wu, Z, Yan, N, Feng, L, Yan, H, Gu, L, Shi, Y. | | 登録日 | 2006-11-02 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.
Nat.Struct.Mol.Biol., 13, 2006
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2O7L
 | | The open-cap conformation of GlpG | | 分子名称: | Protein glpG, nonyl beta-D-glucopyranoside | | 著者 | Ha, Y. | | 登録日 | 2006-12-11 | | 公開日 | 2006-12-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Open-cap conformation of intramembrane protease GlpG.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3B45
 | | Crystal structure of GlpG at 1.9A resolution | | 分子名称: | glpG, nonyl beta-D-glucopyranoside | | 著者 | Wang, Y, Maegawa, S, Akiyama, Y, Ha, Y. | | 登録日 | 2007-10-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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3B44
 | | Crystal structure of GlpG W136A mutant | | 分子名称: | glpG, nonyl beta-D-glucopyranoside | | 著者 | Wang, Y, Maegawa, S, Akiyama, Y, Ha, Y. | | 登録日 | 2007-10-23 | | 公開日 | 2008-01-22 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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3ODJ
 | | Crystal structure of H. influenzae rhomboid GlpG with disordered loop 4, helix 5 and loop 5 | | 分子名称: | Rhomboid protease glpG | | 著者 | Brooks, C.L, Lazareno-Saez, C, Lamoureux, J.S, Mak, M.W, Lemieux, M.J. | | 登録日 | 2010-08-11 | | 公開日 | 2011-02-23 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Insights into Substrate Gating in H. influenzae Rhomboid.
J.Mol.Biol., 407, 2011
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2XOW
 | | Structure of GlpG in complex with a mechanism-based isocoumarin inhibitor | | 分子名称: | 5-AMINO-2-(2-METHOXY-2-OXOETHYL)BENZOIC ACID, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside | | 著者 | Vinothkumar, K.R, Strisovsky, K, Andreeva, A, Christova, Y, Verhelst, S, Freeman, M. | | 登録日 | 2010-08-24 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | The Structural Basis for Catalysis and Substrate Specificity of a Rhomboid Protease
Embo J., 29, 2010
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2XOV
 | | Crystal Structure of E.coli rhomboid protease GlpG, native enzyme | | 分子名称: | GLYCEROL, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside | | 著者 | Vinothkumar, K.R, Strisovsky, K, Andreeva, A, Christova, Y, Verhelst, S, Freeman, M. | | 登録日 | 2010-08-24 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The structural basis for catalysis and substrate specificity of a rhomboid protease.
EMBO J., 29, 2010
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2XTU
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2XTV
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3TXT
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3UBB
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4H1D
 | | Cocrystal structure of GlpG and DFP | | 分子名称: | DIISOPROPYL PHOSPHONATE, Rhomboid protease GlpG | | 著者 | Xue, Y, Ha, Y. | | 登録日 | 2012-09-10 | | 公開日 | 2013-05-01 | | 最終更新日 | 2013-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.8975 Å) | | 主引用文献 | Large lateral movement of transmembrane helix s5 is not required for substrate access to the active site of rhomboid intramembrane protease.
J.Biol.Chem., 288, 2013
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3ZEB
 | | A complex of GlpG with isocoumarin inhibitor covalently bonded to serine 201 and histidine 150 | | 分子名称: | 2-phenylethyl 2-(4-azanyl-2-methanoyl-phenyl)ethanoate, CHLORIDE ION, RHOMBOID PROTEASE GLPG, ... | | 著者 | Vinothkumar, K.R, voskya, O, Kuettler, E.V, Brouwer, A.J, Liskamp, R.M.J, Verhelst, S.H.L. | | 登録日 | 2012-12-04 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Activity-Based Probes for Rhomboid Proteases Discovered in a Mass Spectrometry-Based Assay.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3ZMJ
 | | Structure of E.coli rhomboid protease GlpG in complex with monobactam L61 | | 分子名称: | 2-methylpropyl N-[(1R)-3-oxidanylidene-1-phenyl-propyl]carbamate, CHLORIDE ION, RHOMBOID PROTEASE GLPG, ... | | 著者 | Vinothkumar, K.R, Pierrat, O, Large, J.M, Freeman, M. | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
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3ZMI
 | | Structure of E.coli rhomboid protease GlpG in complex with monobactam L29 | | 分子名称: | RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside, phenyl N-[(1R)-3-oxidanylidene-1-phenyl-propyl]carbamate | | 著者 | Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M. | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
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3ZMH
 | | Structure of E.coli rhomboid protease GlpG in complex with monobactam L62 | | 分子名称: | CHLORIDE ION, CYCLOPENTYL 2-OXO-4-PHENYLAZETIDINE-1-CARBOXYLATE, RHOMBOID PROTEASE GLPG, ... | | 著者 | Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M. | | 登録日 | 2013-02-11 | | 公開日 | 2013-05-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of rhomboid protease in complex with beta-lactam inhibitors defines the S2' cavity.
Structure, 21, 2013
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3ZOT
 | | Structure of E.coli rhomboid protease GlpG in complex with monobactam L29 (data set 2) | | 分子名称: | CHLORIDE ION, RHOMBOID PROTEASE GLPG, nonyl beta-D-glucopyranoside, ... | | 著者 | Vinothkumar, K.R, Pierrat, O.A, Large, J.M, Freeman, M. | | 登録日 | 2013-02-24 | | 公開日 | 2013-05-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.399 Å) | | 主引用文献 | Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity.
Structure, 21, 2013
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4NJN
 | | Crystal Structure of E.coli GlpG at pH 4.5 | | 分子名称: | Rhomboid protease GlpG | | 著者 | Dickey, S.W, Baker, R.P, Cho, S, Urban, S. | | 登録日 | 2013-11-11 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013
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4NJP
 | | Proteolysis inside the membrane is a rate-governed reaction not Driven by substrate affinity | | 分子名称: | Rhomboid protease GlpG | | 著者 | Dickey, S.W, Baker, R.P, Cho, S, Urban, S. | | 登録日 | 2013-11-11 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity.
Cell(Cambridge,Mass.), 155, 2013
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5F5K
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5F5J
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5F5B
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