4N7F
| |
2HO2
| |
1PIN
| PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ... | 著者 | Noel, J.P, Ranganathan, R, Hunter, T. | 登録日 | 1998-06-21 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell(Cambridge,Mass.), 89, 1997
|
|
2OEI
| |
7LP1
| Structure of Nedd4L WW3 domain | 分子名称: | E3 ubiquitin-protein ligase NEDD4-like, GLYCEROL, NITRATE ION | 著者 | Alian, A, Alam, S.L, Thompson, T, Rheinemann, L, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
|
|
3TC5
| Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives | 分子名称: | (11alpha,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate, HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Graeber, M, Janczyk, W, Sperl, B, Elumalai, N, Kozany, C, Hausch, F, Holak, T.A, Berg, T. | 登録日 | 2011-08-08 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Selective targeting of disease-relevant protein binding domains by o-phosphorylated natural product derivatives. Acs Chem.Biol., 6, 2011
|
|
5CQ2
| Crystal Structure of tandem WW domains of ITCH in complex with TXNIP peptide | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-07-21 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP. Biochem.J., 473, 2016
|
|
6VAJ
| Crystal Structure Analysis of human PIN1 | 分子名称: | 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... | 著者 | Seo, H.-S, Dhe-Paganon, S. | 登録日 | 2019-12-17 | 公開日 | 2020-12-30 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat.Chem.Biol., 17, 2021
|
|
2ITK
| human Pin1 bound to D-PEPTIDE | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, D-Peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Noel, J.P, Zhang, Y. | 登録日 | 2006-10-19 | 公開日 | 2007-05-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chem.Biol., 2, 2007
|
|
2ZQT
| |
2F21
| human Pin1 Fip mutant | 分子名称: | PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Jager, M, Zhang, Y, Bowman, M.E, Noel, J.P, Kelly, J.W. | 登録日 | 2005-11-15 | 公開日 | 2006-06-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-function-folding relationship in a WW domain. Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2Q5A
| human Pin1 bound to L-PEPTIDE | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE, Five residue peptide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Noel, J.P, Zhang, Y. | 登録日 | 2007-05-31 | 公開日 | 2007-06-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for high-affinity peptide inhibition of human Pin1. Acs Chem.Biol., 2, 2007
|
|
5VTJ
| Structure of Pin1 WW Domain Sequence 1 Substituted with [S,S]ACPC | 分子名称: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION | 著者 | Mortenson, D.E, Kreitler, D.F, Thomas, N.C, Gellman, S.H, Forest, K.T. | 登録日 | 2017-05-17 | 公開日 | 2018-02-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Evaluation of beta-Amino Acid Replacements in Protein Loops: Effects on Conformational Stability and Structure. Chembiochem, 19, 2018
|
|
7BQG
| Complex structure of SAV1 and Dendrin | 分子名称: | POTASSIUM ION, Protein salvador homolog 1,Dendrin | 著者 | Lin, Z, Zhang, M. | 登録日 | 2020-03-24 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.55010867 Å) | 主引用文献 | A WW Tandem-Mediated Dimerization Mode of SAV1 Essential for Hippo Signaling. Cell Rep, 32, 2020
|
|
6O34
| |
5DZD
| Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-09-25 | 公開日 | 2015-10-14 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Crystal Structure of WW4 domain of ITCH in complex with TXNIP peptide To be Published
|
|
4U86
| Human Pin1 with cysteine sulfonic acid 113 | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
|
|
4REX
| |
3WH0
| Structure of Pin1 Complex with 18-crown-6 | 分子名称: | 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... | 著者 | Lee, C.C, Liu, C.I, Jeng, W.Y, Wang, A.H.J. | 登録日 | 2013-08-20 | 公開日 | 2014-10-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crowning proteins: modulating the protein surface properties using crown ethers. Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
1YW5
| Peptidyl-prolyl isomerase ESS1 from Candida albicans | 分子名称: | peptidyl prolyl cis/trans isomerase | 著者 | Li, Z, Li, H, Devasahayam, G, Gemmill, T, Chaturvedi, V, Hanes, S.D, Van Roey, P. | 登録日 | 2005-02-17 | 公開日 | 2005-04-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The Structure of the Candida albicans Ess1 Prolyl Isomerase Reveals a Well-Ordered Linker that Restricts Domain Mobility Biochemistry, 44, 2005
|
|
7LP3
| Structure of Nedd4L WW3 domain | 分子名称: | Angiomotin, E3 ubiquitin-protein ligase NEDD4-like, SULFATE ION | 著者 | Alian, A, Alam, S.L, Thompson, T, Rheinemann, L, Sundquist, W.I. | 登録日 | 2021-02-11 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Interactions between AMOT PPxY motifs and NEDD4L WW domains function in HIV-1 release. J.Biol.Chem., 297, 2021
|
|
6JJZ
| Crystal Structure of MAGI2 and Dendrin complex | 分子名称: | ACETATE ION, Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2, ... | 著者 | Lin, Z, Zhang, H, Yang, Z, Ji, Z, Zhang, M, Zhu, J. | 登録日 | 2019-02-27 | 公開日 | 2019-09-25 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Decoding WW domain tandem-mediated target recognitions in tissue growth and cell polarity. Elife, 8, 2019
|
|
5DWS
| Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, UNKNOWN ATOM OR ION, txnip | 著者 | Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-09-22 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal Structure of ITCH WW3 domain in complex with TXNIP peptide to be published
|
|
4N7H
| Crystal Structure of the Complex of 3rd WW domain of Human Nedd4 and 1st PPXY Motif of ARRDC3 | 分子名称: | Arrestin domain-containing protein 3, E3 ubiquitin-protein ligase NEDD4, GUANIDINE | 著者 | Qi, S, O'Hayre, M, Gutkind, J.S, Hurley, J. | 登録日 | 2013-10-15 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J.Biol.Chem., 289, 2014
|
|
4U85
| Human Pin1 with cysteine sulfinic acid 113 | 分子名称: | POLYETHYLENE GLYCOL (N=34), Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Li, W, Zhang, Y. | 登録日 | 2014-08-01 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease. Neurobiol.Dis., 76, 2015
|
|