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1A8M
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TUMOR NECROSIS FACTOR ALPHA, R31D MUTANT
分子名称: TUMOR NECROSIS FACTOR ALPHA
著者Reed, C, Fu, Z.-Q, Wu, J, Xue, Y.-N, Harrison, R.W, Chen, M.-J, Weber, I.T.
登録日1998-03-27
公開日1998-06-17
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of TNF-alpha mutant R31D with greater affinity for receptor R1 compared with R2.
Protein Eng., 10, 1997
1ALY
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CRYSTAL STRUCTURE OF HUMAN CD40 LIGAND
分子名称: CD40 LIGAND
著者Karpusas, M, Hsu, Y.M, Thomas, D.
登録日1997-06-05
公開日1997-09-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献2 A crystal structure of an extracellular fragment of human CD40 ligand.
Structure, 3, 1995
1D0G
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CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL
分子名称: APOPTOSIS-2 LIGAND, CHLORIDE ION, DEATH RECEPTOR-5, ...
著者Hymowitz, S.G, Christinger, H.W, Fuh, G, O'Connell, M.P, Kelley, R.F, Ashkenazi, A, de Vos, A.M.
登録日1999-09-09
公開日1999-10-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
Mol.Cell, 4, 1999
1D2Q
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CRYSTAL STRUCTURE OF HUMAN TRAIL
分子名称: TNF-RELATED APOPTOSIS INDUCING LIGAND
著者Cha, S.-S.
登録日1999-09-27
公開日2000-02-11
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8 A resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity.
Immunity, 11, 1999
1D4V
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Crystal structure of trail-DR5 complex
分子名称: DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND
著者Mongkolsapaya, J, Grimes, J.M, Stuart, D.I, Jones, E.Y, Screaton, G.R.
登録日1999-10-06
公開日1999-11-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the TRAIL-DR5 complex reveals mechanisms conferring specificity in apoptotic initiation
Nat.Struct.Biol., 6, 1999
1DG6
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CRYSTAL STRUCTURE OF APO2L/TRAIL
分子名称: APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL), CHLORIDE ION, ZINC ION
著者Hymowitz, S.G, O'ConnelL, M.P, Ultsch, M.H, de Vos, A.M, Kelley, R.F.
登録日1999-11-23
公開日2000-01-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL.
Biochemistry, 39, 2000
1DU3
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Crystal structure of TRAIL-SDR5
分子名称: DEATH RECEPTOR 5, TNF-RELATED APOPTOSIS INDUCING LIGAND, ZINC ION
著者Cha, S.-S, Sung, B.-J, Oh, B.-H.
登録日2000-01-14
公開日2000-09-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
J.Biol.Chem., 275, 2000
1I9R
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STRUCTURE OF CD40L IN COMPLEX WITH THE FAB FRAGMENT OF HUMANIZED 5C8 ANTIBODY
分子名称: CD40 LIGAND, IMMUNOGLOBULIN H, IMMUNOGLOBULIN L, ...
著者Karpusas, M, Lucci, J, Ferrant, J, Benjamin, C, Hsu, Y.-M.
登録日2001-03-20
公開日2002-03-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody.
Structure, 9, 2001
1IQA
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MOUSE RANK LIGAND
分子名称: RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B LIGAND
著者Ito, S, Wakabayashi, K, Ubukata, O, Hayashi, S, Okada, F, Hata, T.
登録日2001-07-11
公開日2002-03-13
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution.
J.Biol.Chem., 277, 2002
1JH5
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Crystal Structure of sTALL-1 of TNF family ligand
分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B
著者Liu, Y, Xu, L, Opalka, N, Shu, H.-B, Zhang, G.
登録日2001-06-27
公開日2002-02-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands.
Cell(Cambridge,Mass.), 108, 2002
1JTZ
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CRYSTAL STRUCTURE OF TRANCE/RANKL CYTOKINE.
分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 11
著者Nelson, C.A, Fremont, D.H.
登録日2001-08-23
公開日2001-09-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the TRANCE/RANKL cytokine reveals determinants of receptor-ligand specificity
J.Clin.Invest., 108, 2001
1KD7
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Crystal structure of an extracellular domain fragment of human BAFF
分子名称: TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 13B
著者Karpusas, M, Cachero, T.G, Qian, F, Boriack-Sjodin, A, Mullen, C, Strauch, K, Hsu, Y.-M, Kalled, S.L.
登録日2001-11-12
公開日2002-11-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Extracellular Human BAFF, a TNF Family Member that Stimulates B Lymphocytes
J.Mol.Biol., 315, 2002
1KXG
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The 2.0 Ang Resolution Structure of BLyS, B Lymphocyte Stimulator.
分子名称: 1,4-DIETHYLENE DIOXIDE, B lymphocyte stimulator, CITRIC ACID, ...
著者Oren, D.A, Li, Y, Volovik, Y, Morris, T.S, Dharia, C, Das, K, Galperina, O, Gentz, R, Arnold, E.
登録日2002-01-31
公開日2002-03-20
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of BLyS receptor recognition.
Nat.Struct.Biol., 9, 2002
1OQD
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Crystal structure of sTALL-1 and BCMA
分子名称: Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OQE
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Crystal structure of sTALL-1 with BAFF-R
分子名称: Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C
著者Zhang, G.
登録日2003-03-07
公開日2003-05-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
1OSG
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Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold
分子名称: BR3 derived PEPTIDE, MAGNESIUM ION, Tumor necrosis factor ligand superfamily member 13B
著者Gordon, N.C, Pan, B, Hymowitz, S.G, Yin, J.P, Kelley, R.F, Cochran, A.G, Yan, M, Dixit, V.M, Fairbrother, W.J, Starovasnik, M.A.
登録日2003-03-19
公開日2003-05-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, 42, 2003
1RJ7
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Crystal structure of EDA-A1
分子名称: Ectodysplasin A
著者Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M.
登録日2003-11-18
公開日2003-12-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Structure, 11, 2003
1RJ8
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The crystal structure of TNF family member EDA-A2
分子名称: ectodysplasin-A isoform EDA-A2
著者Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M.
登録日2003-11-18
公開日2003-12-09
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The Crystal Structure of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity
STRUCTURE, 11, 2003
1S55
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Mouse RANKL Structure at 1.9A Resolution
分子名称: CHLORIDE ION, Tumor necrosis factor ligand superfamily member 11
著者Teale, M.J, Feug, X, Chen, L, Bice, T, Meehan, E.J.
登録日2004-01-19
公開日2005-07-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Murine RANKL Extra Cellular Domain Homotrimer Structure In Space Groups P212121 And H3 At 1.9 And 2.6 Respectively
To be Published
1TNF
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THE STRUCTURE OF TUMOR NECROSIS FACTOR-ALPHA AT 2.6 ANGSTROMS RESOLUTION. IMPLICATIONS FOR RECEPTOR BINDING
分子名称: TUMOR NECROSIS FACTOR-ALPHA
著者Eck, M.J, Sprang, S.R.
登録日1989-08-25
公開日1990-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.
J.Biol.Chem., 264, 1989
1TNR
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CRYSTAL STRUCTURE OF THE SOLUBLE HUMAN 55 KD TNF RECEPTOR-HUMAN TNF-BETA COMPLEX: IMPLICATIONS FOR TNF RECEPTOR ACTIVATION
分子名称: TUMOR NECROSIS FACTOR BETA, TUMOR NECROSIS FACTOR RECEPTOR P55
著者Banner, D.W.
登録日1994-05-09
公開日1994-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Cell(Cambridge,Mass.), 73, 1993
1U5X
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Crystal structure of murine APRIL at pH 5.0
分子名称: Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Y
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Crystal structure of murine APRIL, pH 8.0
分子名称: Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1U5Z
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The Crystal structure of murine APRIL, pH 8.5
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13
著者Wallweber, H.J, Compaan, D.M, Starovasnik, M.A, Hymowitz, S.G.
登録日2004-07-28
公開日2004-10-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of A Proliferation-inducing Ligand, APRIL.
J.Mol.Biol., 343, 2004
1XU1
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The crystal structure of APRIL bound to TACI
分子名称: NICKEL (II) ION, Tumor necrosis factor ligand superfamily member 13, Tumor necrosis factor receptor superfamily member 13B
著者Hymowitz, S.G, Patel, D.R, Wallweber, H.J.A, Runyon, S, Yan, M, Yin, J, Shriver, S.K, Gordon, N.C, Pan, B, Skelton, N.J, Kelley, R.F, Starovasnik, M.A.
登録日2004-10-25
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high-affinity ligand binding
J.Biol.Chem., 280, 2005

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