PDB: 54 件ウェブページステータス検索Chemie searchBIRD

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1BYV	GLYCOSYLATED EEL CALCITONIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CALCITONIN) 著者 Hashimoto, Y, Toma, K, Nishikido, J, Yamamoto, K, Haneda, K, Inazu, T, Valentine, K.G, Opella, S.J. 登録日 1998-10-16 公開日 1998-10-28 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 Effects of glycosylation on the structure and dynamics of eel calcitonin in micelles and lipid bilayers determined by nuclear magnetic resonance spectroscopy. Biochemistry, 38, 1999
1BZB	GLYCOSYLATED EEL CALCITONIN 分子名称: PROTEIN (CALCITONIN), alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Hashimoto, Y, Toma, K, Nishikido, J, Yamamoto, K, Haneda, K, Inazu, T, Valentine, K, Opella, S.J. 登録日 1998-10-27 公開日 1998-11-11 最終更新日 2020-07-29 実験手法 SOLUTION NMR 主引用文献 Effects of glycosylation on the structure and dynamics of eel calcitonin in micelles and lipid bilayers determined by nuclear magnetic resonance spectroscopy. Biochemistry, 38, 1999
1BKU	EFFECTS OF GLYCOSYLATION ON THE STRUCTURE AND DYNAMICS OF EEL CALCITONIN, NMR, 10 STRUCTURES 分子名称: CALCITONIN 著者 Hashimoto, Y, Nishikido, J, Toma, K, Yamamoto, K, Haneda, K, Inazu, T, Valentine, K, Opella, S.J. 登録日 1998-07-13 公開日 1999-01-13 最終更新日 2022-02-16 実験手法 SOLUTION NMR 主引用文献 Effects of glycosylation on the structure and dynamics of eel calcitonin in micelles and lipid bilayers determined by nuclear magnetic resonance spectroscopy. Biochemistry, 38, 1999
1FB9	EFFECTS OF S-SULFONATION ON THE SOLUTION STRUCTURE OF SALMON CALCITONIN 分子名称: CALCITONIN ANALOGUE 著者 Wu, H, Mao, J, Wang, Y, Dou, H. 登録日 2000-07-14 公開日 2003-07-01 最終更新日 2018-06-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and biological activity of recombinant salmon calcitonin S-sulfonated analog Biochem.Biophys.Res.Commun., 306, 2003
2G48	crystal structure of human insulin-degrading enzyme in complex with amylin 分子名称: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Islet amyloid polypeptide 著者 Shen, Y, Tang, W.-J. 登録日 2006-02-21 公開日 2006-10-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature, 443, 2006
2KB8	The dynamic alpha-helix structure of micelle-bound human amylin. 分子名称: Islet amyloid polypeptide 著者 Patil, S.M, Xu, S, Sheftic, S.R, Alexandrescu, A.T. 登録日 2008-11-21 公開日 2009-02-24 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Dynamic alpha-helix structure of micelle-bound human amylin. J.Biol.Chem., 284, 2009
2KJ7	Three-Dimensional NMR Structure of Rat Islet Amyloid Polypeptide in DPC micelles 分子名称: Islet amyloid polypeptide 著者 Nanga, R, Brender, J.R, Xu, J, Hartman, K, Subramanian, V, Ramamoorthy, A. 登録日 2009-05-22 公開日 2009-06-23 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy. J.Am.Chem.Soc., 131, 2009
3G7W	Islet Amyloid Polypeptide (IAPP or Amylin) Residues 1 to 22 fused to Maltose Binding Protein 分子名称: GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... 著者 Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. 登録日 2009-02-11 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
3G7V	Islet Amyloid Polypeptide (IAPP or Amylin) fused to Maltose Binding Protein 分子名称: GLYCEROL, Maltose-binding periplasmic protein, Islet amyloid polypeptide fusion protein, ... 著者 Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D. 登録日 2009-02-10 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process Protein Sci., 18, 2009
3HGZ	Crystal structure of human insulin-degrading enzyme in complex with amylin 分子名称: Insulin-degrading enzyme, Islet amyloid polypeptide, ZINC ION 著者 Guo, Q, Bian, Y, Tang, W.J. 登録日 2009-05-14 公開日 2009-12-08 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Molecular Basis for the Recognition and Cleavages of IGF-II, TGF-alpha, and Amylin by Human Insulin-Degrading Enzyme. J.Mol.Biol., 395, 2010
2L86	Solution NMR structure of human amylin in SDS micelles at pH 7.3 分子名称: Islet amyloid polypeptide 著者 Nanga, R, Brender, J.R, Vivekanandan, S, Ramamoorthy, A. 登録日 2011-01-04 公開日 2011-07-13 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure and membrane orientation of IAPP in its natively amidated form at physiological pH in a membrane environment. Biochim.Biophys.Acta, 1808, 2011
2L7S	Determination of the three-dimensional structure of adrenomedullin, a first step towards the analysis of its interactions with receptors and small molecules 分子名称: Adrenomedullin 著者 Jimenez-Barbero, J, Perez-Castells, J, Nieto, L. 登録日 2010-12-21 公開日 2011-09-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules. Biopolymers, 97, 2012
5II0	Crystal structure of the human calcitonin receptor ectodomain in complex with a truncated salmon calcitonin analogue 分子名称: Calcitonin, Calcitonin receptor, SODIUM ION, ... 著者 Johansson, E, Reedtz-Runge, S. 登録日 2016-03-01 公開日 2016-05-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography. J.Biol.Chem., 291, 2016
5K5G	Structure of human islet amyloid polypeptide in complex with an engineered binding protein 分子名称: HI18, Islet amyloid polypeptide 著者 Mirecka, E.A, Feuerstein, S, Gremer, L, Schroeder, G.F, Stoldt, M, Willbold, D, Hoyer, W. 登録日 2016-05-23 公開日 2016-10-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 beta-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor. Sci Rep, 6, 2016
5MGQ	Solution structure of oxidized and amidated human IAPP (1-37), the diabetes II peptide. 分子名称: Islet amyloid polypeptide 著者 Rodriguez Camargo, D.C, Tripsianes, K, Reif, B. 登録日 2016-11-21 公開日 2017-03-29 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes. Sci Rep, 7, 2017
6NIY	A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex 分子名称: Calcitonin, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 dal Maso, E, Glukhova, A, Zhu, Y, Garcia-Nafria, J, Tate, C.G, Atanasio, S, Reynolds, C.A, Ramirez-Aportela, E, Carazo, J.-M, Hick, C.A, Furness, S.G.B, Hay, D.L, Liang, Y.-L, Miller, L.J, Christopoulos, A, Wang, M.-W, Wootten, D, Sexton, P.M. 登録日 2019-01-02 公開日 2019-01-23 最終更新日 2020-04-08 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 The Molecular Control of Calcitonin Receptor Signaling. Acs Pharmacol Transl Sci, 2, 2019
6PFO	Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin, Maltodextrin-binding protein,Calcitonin receptor, ... 著者 Lee, S, Pioszak, A.A. 登録日 2019-06-21 公開日 2020-02-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics. J.Mol.Biol., 432, 2020
6UCK	proIAPP in DPC Micelles - Two-Conformer Ensemble Refinement, Bent Conformer 分子名称: Islet amyloid polypeptide 著者 DeLisle, C.F, Malooley, A.L, Banerjee, I, Lorieau, J.L. 登録日 2019-09-16 公開日 2020-02-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Pro-islet amyloid polypeptide in micelles contains a helical prohormone segment. Febs J., 287, 2020
6UCJ	proIAPP in DPC Micelles - Two-Conformer Ensemble Refinement, Open Conformer 分子名称: Islet amyloid polypeptide 著者 DeLisle, C.F, Malooley, A.L, Banerjee, I, Lorieau, J.L. 登録日 2019-09-16 公開日 2020-02-26 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Pro-islet amyloid polypeptide in micelles contains a helical prohormone segment. Febs J., 287, 2020
6Y1A	Amyloid fibril structure of islet amyloid polypeptide 分子名称: AMINO GROUP, Islet amyloid polypeptide 著者 Roeder, C, Kupreichyk, T, Gremer, L, Schaefer, L.U, Pothula, K.R, Ravelli, R.B.G, Willbold, D, Hoyer, W, Schroder, G.F. 登録日 2020-02-11 公開日 2020-03-04 最終更新日 2020-07-22 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-beta fibrils. Nat.Struct.Mol.Biol., 27, 2020
6UUN	CryoEM Structure of the active Adrenomedullin 1 receptor G protein complex with adrenomedullin peptide 分子名称: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-10-30 公開日 2020-03-25 最終更新日 2020-04-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins. Acs Pharmacol Transl Sci, 3, 2020
6UUS	CryoEM Structure of the active Adrenomedullin 2 receptor G protein complex with adrenomedullin peptide 分子名称: ADM, Calcitonin gene-related peptide type 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Belousoff, M.J, Liang, Y.L, Sexton, P, Danev, R. 登録日 2019-10-31 公開日 2020-04-01 最終更新日 2020-04-29 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins. Acs Pharmacol Transl Sci, 3, 2020
6VW2	Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils 分子名称: Islet amyloid polypeptide (SUMO-tagged) 著者 Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. 登録日 2020-02-18 公開日 2020-06-10 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM structure and inhibitor design of human IAPP (amylin) fibrils. Nat.Struct.Mol.Biol., 27, 2020
6ZRF	amyloid structure of amylin (IAPP - islet amyloid polypeptide) 分子名称: Islet amyloid polypeptide 著者 Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E. 登録日 2020-07-13 公開日 2020-09-30 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nat.Struct.Mol.Biol., 27, 2020
6ZRQ	two-protofilament amyloid structure of S20G variant of human amylin (IAPP - islet amyloid polypeptide) 分子名称: Islet amyloid polypeptide 著者 Gallardo, R.U, Iadanza, M.G, Ranson, N.A, Radford, S.E. 登録日 2020-07-14 公開日 2020-09-30 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly. Nat.Struct.Mol.Biol., 27, 2020

 

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