PDB: 51 件ウェブページステータス検索Chemie searchBIRD

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3RI4	Ets1 cooperative binding to widely separated sites on promoter DNA 分子名称: Isoform Ets-1 p27 of Protein C-ets-1, TCR alpha promoter DNA 著者 Babayeva, N.D, Mino, K, Tahirov, T.H. 登録日 2011-04-12 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of ets1 cooperative binding to widely separated sites on promoter DNA. Plos One, 7, 2012
3MFK	Ets1 complex with stromelysin-1 promoter DNA 分子名称: Protein C-ets-1, stromelysin-1 promoter DNA 著者 Babayeva, N.D, Mino, K, Tahirov, T.H. 登録日 2010-04-02 公開日 2010-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA. Cell Cycle, 9, 2010
2STW	SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, RESTRAINED REGULARIZED MEAN STRUCTURE 分子名称: DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3'), ETS1 著者 Clore, G.M, Werner, M.H, Gronenborn, A.M. 登録日 1996-08-05 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Correction of the NMR structure of the ETS1/DNA complex. J.Biomol.NMR, 10, 1997
2STT	SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, 25 STRUCTURES 分子名称: DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3'), ETS1 著者 Clore, G.M, Werner, M.H, Gronenborn, A.M. 登録日 1996-08-05 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Correction of the NMR structure of the ETS1/DNA complex. J.Biomol.NMR, 10, 1997
6DA1	ETS1 in complex with synthetic SRR mimic 分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide 著者 Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. 登録日 2018-05-01 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.000127 Å) 主引用文献 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
6DAT	ETS1 in complex with synthetic SRR mimic 分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide 著者 Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P. 登録日 2018-05-02 公開日 2019-01-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35002637 Å) 主引用文献 The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. J. Mol. Biol., 431, 2019
5ZMC	Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2 分子名称: DNA (5'-D(P*CP*GP*GP*GP*GP*AP*CP*CP*CP*GP*GP*AP*AP*GP*GP*G)-3'), DNA (5'-D(P*GP*CP*CP*CP*TP*TP*CP*CP*GP*GP*GP*TP*CP*CP*CP*C)-3'), Nuclear factor NF-kappa-B p100 subunit, ... 著者 Xu, X, Bharath, S.R, Song, H. 登録日 2018-04-02 公開日 2018-09-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun, 9, 2018
2KMD	Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP 分子名称: Protein C-ets-1 著者 Nelson, M.L, Kang, H, Lee, G.M, Blaszczak, A.G, Lau, D.K.W, McIntosh, L.P, Graves, B.J. 登録日 2009-07-27 公開日 2010-05-05 最終更新日 2012-03-21 実験手法 SOLUTION NMR 主引用文献 Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. Proc.Natl.Acad.Sci.USA, 107, 2010
4L0Y	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 1) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
4L18	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 3) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', GLYCEROL, ... 著者 Tahirov, T.H. 登録日 2013-06-02 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
4L0Z	Crystal structure of Runx1 and Ets1 bound to TCR alpha promoter (crystal form 2) 分子名称: 5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Protein C-ets-1, ... 著者 Tahirov, T.H. 登録日 2013-06-01 公開日 2014-03-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of Ets1 activation by Runx1. Leukemia, 28, 2014
3WTW	Crystal structure of the complex comprised of ETS1(K167A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTY	Crystal structure of the complex comprised of ETS1(G333P), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTX	Crystal structure of the complex comprised of ETS1(Y329A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTV	Crystal structure of the complex comprised of ETS1(V170G), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTS	Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTT	Crystal structure of the complex comprised of phosphorylated ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTU	Crystal structure of the complex comprised of ETS1 (V170A), RUNX1, CBFBETA, and the tcralpha gene enhancer DNA 分子名称: Core-binding factor subunit beta, DNA (5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WU1	Crystal structure of the ETS1-RUNX1-DNA ternary complex 分子名称: DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), Protein C-ets-1, ... 著者 Tahirov, T.H, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WTZ	Crystal structure of ETS-1 DNA binding and autoinhibitory domains (276-441) 分子名称: Protein C-ets-1 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
3WU0	Crystal structure of phosphorylated ETS-1 DNA binding and autoinhibitory domains (276-441) 分子名称: Protein C-ets-1 著者 Shiina, M, Hamada, K, Ogata, K. 登録日 2014-04-21 公開日 2014-08-20 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427, 2015
4LG0	Structure of a ternary FOXO1-ETS1 DNA complex 分子名称: CALCIUM ION, DNA (5'-D(*DAP*DAP*DAP*DCP*DAP*DAP*DTP*DAP*DAP*DCP*DAP*DGP*DGP*DAP*DAP*DAP*DCP*DCP*DGP*DTP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DAP*DCP*DGP*DGP*DTP*DTP*DTP*DCP*DCP*DTP*DGP*DTP*DTP*DAP*DTP*DTP*DGP*DT)-3'), ... 著者 Birrane, G, Choy, W.C, Datta, D, Geiger, C.A, Grant, M.A. 登録日 2013-06-27 公開日 2014-07-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Structure of a ternary FOXO1-ETS1 DNA complex To be Published
2NNY	Crystal structure of the Ets1 dimer DNA complex. 分子名称: 5'-D(*A*CP*TP*CP*CP*AP*GP*GP*AP*AP*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*TP*CP*T)-3', 5'-D(*T*AP*GP*AP*CP*AP*GP*GP*AP*AP*GP*CP*AP*CP*TP*TP*CP*CP*TP*GP*GP*AP*G)-3', C-ets-1 protein 著者 Lamber, E.P, Kachalova, G.S, Wilmanns, M. 登録日 2006-10-24 公開日 2008-03-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization. Embo J., 27, 2008
1GVJ	ETS-1 DNA BINDING AND AUTOINHIBITORY DOMAINS 分子名称: C-ETS-1 PROTEIN 著者 Tahirov, T.H, Ogata, K. 登録日 2002-02-14 公開日 2004-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Crystal Structure of C-Ets-1 DNA-Binding and Autoinhibitory Domains To be Published
1R36	NMR-based structure of autoinhibited murine Ets-1 deltaN301 分子名称: C-ets-1 protein 著者 Lee, G.M, Donaldson, L.W, Pufall, M.A, Kang, H.-S, Pot, I, Graves, B.J, McIntosh, L.P. 登録日 2003-09-30 公開日 2004-11-09 最終更新日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition J.Biol.Chem., 280, 2005

 

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