PDB: 45817 件ウェブページステータス検索Chemie searchBIRD

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8U0O	Synaptic complex of human DNA polymerase Lambda DL variant engaged on a DNA double-strand break containing an unpaired 3' primer terminus 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*CP*GP*CP*GP*GP*CP*A)-3'), ... 著者 Kaminski, A.M, Pedersen, L.C, Bebenek, K, Kunkel, T.A, Chiruvella, K.K, Ramsden, D.A. 登録日 2023-08-29 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 DNA polymerase lambda Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining. DNA Repair (Amst), 136, 2024
8U0P	Synaptic complex of human DNA polymerase Lambda DL variant engaged on a noncomplementary DNA double-strand break 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), ... 著者 Kaminski, A.M, Pedersen, L.C, Bebenek, K, Kunkel, T.A, Chiruvella, K.K, Ramsden, D.A. 登録日 2023-08-29 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 DNA polymerase lambda Loop1 variant yields unexpected gain-of-function capabilities in nonhomologous end-joining. DNA Repair (Amst), 136, 2024
2PFP	DNA Polymerase lambda in complex with DNA and dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
5T14	DNA polymerase kappa extending beyond a bulky major benzo[a]pyrene adduct 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA, DNA polymerase kappa, ... 著者 Jha, V.K, Ling, H. 登録日 2016-08-17 公開日 2016-12-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa. DNA Repair (Amst.), 49, 2017
6P5C	Bacillus Fragment DNA polymerase mutant I716M 分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*TP*GP*AP*TP*CP*G)-3'), DNA polymerase I, ... 著者 Wu, E.Y. 登録日 2019-05-30 公開日 2020-03-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The importance of Ile716 toward the mutagenicity of 8-Oxo-2'-deoxyguanosine with Bacillus fragment DNA polymerase. DNA Repair (Amst.), 89, 2020
8E11	Structure of mouse DNA polymerase Beta (PolB) mutant 分子名称: ACETATE ION, DNA polymerase beta, MALONIC ACID 著者 Sharma, N, Thompson, M.K, Prakash, A. 登録日 2022-08-09 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Pol beta /XRCC1 heterodimerization dictates DNA damage recognition and basal Pol beta protein levels without interfering with mouse viability or fertility. DNA Repair (Amst), 123, 2023
2P66	Human DNA Polymerase beta complexed with tetrahydrofuran (abasic site) containing DNA 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*C)-3'), DNA (5'-D(P*(3DR)P*GP*TP*CP*GP*G)-3'), ... 著者 Prasad, R, Batra, V.K, Yang, X.-P, Krahn, J.M, Pedersen, L.C, Beard, W.A, Wilson, S.H. 登録日 2007-03-16 公開日 2007-04-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural insight into the DNA Polymerase beta deoxyribose phosphate lyase mechanism DNA REPAIR, 4, 2005
6UG1	Sequence impact in DNA duplex opening by the Rad4/XPC nucleotide excision repair complex 分子名称: DNA (5'-D(*AP*TP*TP*GP*TP*AP*GP*GP*GP*AP*TP*GP*TP*CP*GP*AP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*(G47)P*AP*CP*AP*TP*CP*CP*CP*CP*TP*AP*CP*AP*A)-3'), DNA repair protein RAD4, ... 著者 Paul, D, Min, J.-H. 登録日 2019-09-25 公開日 2021-03-31 最終更新日 2021-09-08 実験手法 X-RAY DIFFRACTION (2.833 Å) 主引用文献 Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex. DNA Repair (Amst), 107, 2021
2PFO	DNA Polymerase lambda in complex with DNA and dUPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
8E10	Structure of mouse polymerase beta 分子名称: DNA polymerase beta, MALONIC ACID 著者 Thompson, M.K, Sharma, N, Prakash, A. 登録日 2022-08-09 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Pol beta /XRCC1 heterodimerization dictates DNA damage recognition and basal Pol beta protein levels without interfering with mouse viability or fertility. DNA Repair (Amst), 123, 2023
3TWL	Crystal structure of Arabidopsis thaliana FPG 分子名称: Formamidopyrimidine-DNA glycosylase 1, GLYCEROL 著者 Duclos, S, Aller, P, Wallace, S.S, Doublie, S. 登録日 2011-09-22 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. Dna Repair, 11, 2012
3TWK	Crystal structure of arabidopsis thaliana FPG 分子名称: Formamidopyrimidine-DNA glycosylase 1, GLYCEROL 著者 Duclos, S, Aller, P, Wallace, S.S, Doublie, S. 登録日 2011-09-22 公開日 2012-07-25 最終更新日 2012-08-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. Dna Repair, 11, 2012
4HSB	S. pombe 3-methyladenine DNA glycosylase-like protein Mag2 bound to damaged DNA 分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*CP*CP*CP*GP*TP*TP*AP*GP*TP*CP*C)-3'), DNA (5'-D(P*GP*GP*AP*CP*TP*(3DR)P*AP*CP*GP*GP*G)-3'), ... 著者 Adhikary, S, Eichman, B.F. 登録日 2012-10-29 公開日 2013-01-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Non-productive DNA damage binding by DNA glycosylase-like protein Mag2 from Schizosaccharomyces pombe. Dna Repair, 12, 2013
7LYT	Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and Phosphorothioate-DNA 分子名称: CasPhi, MAGNESIUM ION, NTS-DNA*, ... 著者 Pausch, P, Soczek, K, Nogales, E, Doudna, J. 登録日 2021-03-08 公開日 2021-08-04 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 DNA interference states of the hypercompact CRISPR-Cas Phi effector. Nat.Struct.Mol.Biol., 28, 2021
2PFQ	Manganese promotes catalysis in a DNA polymerase lambda-DNA crystal 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
7LYS	Cryo-EM structure of CasPhi-2 (Cas12j) bound to crRNA and DNA 分子名称: CasPhi-2, NTS-DNA, TS-DNA, ... 著者 Pausch, P, Soczek, K, Nogales, E, Doudna, J. 登録日 2021-03-08 公開日 2021-08-04 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 DNA interference states of the hypercompact CRISPR-Cas Phi effector. Nat.Struct.Mol.Biol., 28, 2021
2PFN	Na in the active site of DNA Polymerase lambda 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase lambda, Downstream Primer, ... 著者 Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Pedersen, L.C, Kunkel, T.A. 登録日 2007-04-05 公開日 2007-05-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Role of the catalytic metal during polymerization by DNA polymerase lambda. DNA Repair, 6, 2007
6VPC	Structure of the SpCas9 DNA adenine base editor - ABE8e 分子名称: CRISPR-associated endonuclease Cas9, Cas9 (SpCas9) single-guide RNA (sgRNA), DNA non-target strand (NTS), ... 著者 Knott, G.J, Lapinaite, A, Doudna, J.A. 登録日 2020-02-03 公開日 2020-07-29 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 DNA capture by a CRISPR-Cas9-guided adenine base editor. Science, 369, 2020
5UX0	X-ray crystal structure of Marinitoga piezophila Argonaute in complex with 5' OH guide RNA and target DNA 分子名称: Argonaute protein, DNA (5'-D(P*AP*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*CP*C)-3'), RNA (5'-R(*G*GP*UP*AP*CP*AP*AP*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*AP*U)-3') 著者 Doxzen, K.W, Doudna, J.A. 登録日 2017-02-21 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.197 Å) 主引用文献 DNA recognition by an RNA-guided bacterial Argonaute. PLoS ONE, 12, 2017
3I0X	Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing adenine opposite to 8-oxoG 分子名称: 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*AP*TP*GP*GP*A)-3', 8-oxoguanine-DNA-glycosylase, ... 著者 Faucher, F, Doublie, S. 登録日 2009-06-25 公開日 2009-09-29 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. Dna Repair, 8, 2009
3I0W	Crystal structure of Clostridium acetobutylicum 8-oxoguanine glycosylase/lyase in complex with dsDNA containing cytosine opposite to 8-oxoG 分子名称: 1,2-ETHANEDIOL, 5'-D(*AP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*A)-3', ... 著者 Faucher, F, Doublie, S. 登録日 2009-06-25 公開日 2009-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural basis for the lack of opposite base specificity of Clostridium acetobutylicum 8-oxoguanine DNA glycosylase. Dna Repair, 8, 2009
1Z56	Co-Crystal Structure of Lif1p-Lig4p 分子名称: DNA ligase IV, Ligase interacting factor 1 著者 Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L. 登録日 2005-03-17 公開日 2006-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.92 Å) 主引用文献 Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. DNA REPAIR, 5, 2006
3TWM	Crystal structure of Arabidopsis thaliana FPG 分子名称: 5'-D(*AP*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*GP*TP*GP*GP*AP*CP*GP*C)-3', Formamidopyrimidine-DNA glycosylase 1 著者 Duclos, S, Aller, P, Wallace, S.S, Doublie, S. 登録日 2011-09-22 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and biochemical studies of a plant formamidopyrimidine-DNA glycosylase reveal why eukaryotic Fpg glycosylases do not excise 8-oxoguanine. Dna Repair, 11, 2012
7THB	Crystal structure of an RNA-5'/DNA-3' strand exchange junction 分子名称: DNA (5'-D(*GP*AP*TP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*TP*AP*AP*GP*CP*AP*GP*CP*AP*TP*C)-3'), RNA (5'-R(*AP*GP*CP*UP*UP*AP*C)-3') 著者 Cofsky, J.C, Knott, G.J, Gee, C.L, Doudna, J.A. 登録日 2022-01-10 公開日 2022-04-27 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Crystal structure of an RNA/DNA strand exchange junction. Plos One, 17, 2022
7P0L	Crystal structure of S.pombe Mdb1 BRCT domains in complex with a H2A phosphopeptide 分子名称: DNA damage response protein Mdb1, Histone H2A-beta 著者 Day, M, Oliver, A.W, Pearl, L.H. 登録日 2021-06-29 公開日 2021-12-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. DNA Repair (Amst), 108, 2021

 

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