PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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7JNR	Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propionamide 分子名称: Carbonic anhydrase 2, GLYCEROL, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, ... 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.443 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
1ZWC	STRUCTURE OF BOVINE PARATHYROID HORMONE FRAGMENT 1-37, NMR, 10 STRUCTURES 分子名称: PARATHYROID HORMONE 著者 Roesch, P, Marx, U.C. 登録日 1996-06-17 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37). Biochem.Biophys.Res.Commun., 267, 2000
1ZWB	STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 2-37, NMR, 10 STRUCTURES 分子名称: PARATHYROID HORMONE 著者 Roesch, P, Marx, U.C. 登録日 1996-06-17 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure-activity relation of NH2-terminal human parathyroid hormone fragments. J.Biol.Chem., 273, 1998
1ZWE	STRUCTURE OF HUMAN PARATHYROID HORMONE FRAGMENT 4-37, NMR, 10 STRUCTURES 分子名称: PARATHYROID HORMONE 著者 Roesch, P, Marx, U.C. 登録日 1996-06-17 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure-activity relation of NH2-terminal human parathyroid hormone fragments. J.Biol.Chem., 273, 1998
7JNW	Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)isobutyramide 分子名称: 2-methyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.292 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
6S5O	Non-square conformations of KtrA E125Q mutant rings with bound ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Ktr system potassium uptake protein A 著者 Teixeira-Duarte, C.M, Fonseca, F, Morais-Cabral, J.H. 登録日 2019-07-02 公開日 2020-01-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.983 Å) 主引用文献 Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site. Elife, 8, 2019
4IE7	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with citrate and rhein (RHN) 分子名称: 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, CITRATE ANION, ... 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6004 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
1ZWG	SUCCINYL HUMAN PARATHYROID HORMONE 4-37, NMR, 10 STRUCTURES 分子名称: PARATHYROID HORMONE 著者 Roesch, P, Marx, U.C. 登録日 1996-06-17 公開日 1997-06-16 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Strukturen Verschiedener Parathormonfragmente in Loesung, 1996
7JO2	Carbonic Anhydrase IX Mimic Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)isobutyramide 分子名称: 2-methyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, Carbonic anhydrase 2, ZINC ION 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.307 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
6S6D	Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. 登録日 2019-07-02 公開日 2019-10-16 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
2GCG	Ternary Crystal Structure of Human Glyoxylate Reductase/Hydroxypyruvate Reductase 分子名称: (2R)-2,3-DIHYDROXYPROPANOIC ACID, Glyoxylate reductase/hydroxypyruvate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Booth, M.P.S, Conners, R, Rumsby, G, Brady, R.L. 登録日 2006-03-14 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase J.Mol.Biol., 360, 2006
3G9C	Crystal structure of the product Bacillus anthracis glmS ribozyme 分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GLMS RIBOZYME, MAGNESIUM ION, ... 著者 Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. 登録日 2009-02-13 公開日 2009-11-03 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme Biochemistry, 48, 2009
1AYJ	DETERMINATION OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF RAPHANUS SATIVUS ANTIFUNGAL PROTEIN 1 (RS-AFP1) BY 1H NMR, 20 STRUCTURES 分子名称: ANTIFUNGAL PROTEIN 1 著者 Fant, F, Borremans, F.A.M. 登録日 1997-11-05 公開日 1998-01-28 最終更新日 2024-10-23 実験手法 SOLUTION NMR 主引用文献 Determination of the three-dimensional solution structure of Raphanus sativus antifungal protein 1 by 1H NMR. J.Mol.Biol., 279, 1998
5A5B	Structure of the 26S proteasome-Ubp6 complex 分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... 著者 Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. 登録日 2015-06-17 公開日 2015-07-22 最終更新日 2025-04-09 実験手法 ELECTRON MICROSCOPY (9.5 Å) 主引用文献 Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
2ACS	AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE 分子名称: ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. 登録日 1994-04-15 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate. Biochemistry, 33, 1994
3NVQ	Molecular mechanism of guidance cue recognition 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-C1, ... 著者 Juo, Z, Liu, H, Shim, A, Focia, P, Chen, X, Garcia, C, He, X. 登録日 2010-07-08 公開日 2010-09-15 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1. Cell(Cambridge,Mass.), 142, 2010
6VYG	Cryo-EM structure of Plasmodium vivax hexokinase (Closed state) 分子名称: Phosphotransferase 著者 Srivastava, S.S, Darling, J.E, Suryadi, J, Morris, J.C, Drew, M.E, Subramaniam, S. 登録日 2020-02-26 公開日 2020-05-06 最終更新日 2025-06-04 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Plasmodium vivax and human hexokinases share similar active sites but display distinct quaternary architectures Iucrj, 7, 2020
7JNV	Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)butyramide 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
7JNZ	Carbonic Anhydrase II Complexed with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide 分子名称: Carbonic anhydrase 2, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Andring, J.T, McKenna, R. 登録日 2020-08-05 公開日 2020-11-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.289 Å) 主引用文献 Structural Basis of Nanomolar Inhibition of Tumor-Associated Carbonic Anhydrase IX: X-Ray Crystallographic and Inhibition Study of Lipophilic Inhibitors with Acetazolamide Backbone. J.Med.Chem., 63, 2020
3US1	Structure of p63 DNA Binding Domain in Complex with a 22 Base Pair Response Element Containing a Two Base Pair "GC" Spacer Between Half Sites 分子名称: 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*GP*CP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3', Tumor protein 63, ZINC ION 著者 Chen, C, Herzberg, O. 登録日 2011-11-22 公開日 2012-02-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Pliable DNA Conformation of Response Elements Bound to Transcription Factor p63. J.Biol.Chem., 287, 2012
2ACR	AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE 分子名称: ALDOSE REDUCTASE, CACODYLATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. 登録日 1994-04-15 公開日 1994-07-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate. Biochemistry, 33, 1994
3GC6	Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ecto-NAD+ glycohydrolase (CD38 molecule), SULFATE ION 著者 Egea, P.F, Muller-Steffner, H, Stroud, R.M, Oppenheimer, N, Kellenberger, E, Schuber, F. 登録日 2009-02-21 公開日 2010-03-02 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. Plos One, 7, 2012
5A37	Mutations in the Calponin homology domain of Alpha-Actinin-2 affect Actin binding and incorporation in muscle. 分子名称: HUMAN ALPHA-ACTININ-2 著者 Haywood, N.J, Wolny, M, Trinh, C.H, Shuping, Y, Edwards, T.A, Peckham, M. 登録日 2015-05-27 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Hypertrophic Cardiomyopathy Mutations in the Calponin-Homology Domain of Actn2 Affect Actin Binding and Cardiomyocyte Z-Disc Incorporation. Biochem.J., 473, 2016
4IE6	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) 分子名称: Alpha-ketoglutarate-dependent dioxygenase FTO, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ZINC ION 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5036 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
3GDN	Almond hydroxynitrile lyase in complex with benzaldehyde 分子名称: (2R)-hydroxy(phenyl)ethanenitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Dreveny, I, Gruber, K, Kratky, C. 登録日 2009-02-24 公開日 2009-03-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activity. Biochemistry, 48, 2009

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