6S6D
Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex
Summary for 6S6D
Entry DOI | 10.2210/pdb6s6d/pdb |
Descriptor | Ras-related GTP-binding protein A, Ras-related GTP-binding protein C, GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | small gtpases, mtorc1 activator, roadblock domain, gtpase domain, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 163987.78 |
Authors | Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Kaufman, J.,Williams, R.L. (deposition date: 2019-07-02, release date: 2019-10-16, Last modification date: 2024-05-15) |
Primary citation | Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Berndt, A.,Kaufman, J.,Johnson, C.M.,Santhanam, B.,Rogala, K.B.,Sabatini, D.M.,Williams, R.L. Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366:203-210, 2019 Cited by PubMed: 31601764DOI: 10.1126/science.aax3939 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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