5UO3
 
 | | Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile | | 分子名称: | 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-[(methylamino)methyl]benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2017-01-31 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.
J. Med. Chem., 60, 2017
|
|
2PJQ
 | | Crystal structure of Q88U62_LACPL from Lactobacillus plantarum. Northeast Structural Genomics target LpR71 | | 分子名称: | Uncharacterized protein lp_2664 | | 著者 | Benach, J, Su, M, Seetharaman, J, Forouhar, F, Chen, C.X, Cunningham, K, Ma, L.-C, Owens, L, Baran, M, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-04-16 | | 公開日 | 2007-05-01 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of Q88U62_LACPL from Lactobacillus plantarum.
To be Published
|
|
6CRH
 | |
6CRS
 | |
5VL6
 | |
4Z0D
 | | Crystal structure of FVO strain Plasmodium falciparum AMA1 in complex with the RON2hp [Phe2038Trp] peptide | | 分子名称: | Apical membrane antigen 1, Rhoptry neck protein 2 | | 著者 | Wang, G, McGowan, S, Norton, R.S, Scanlon, M.J. | | 登録日 | 2015-03-26 | | 公開日 | 2016-08-03 | | 最終更新日 | 2020-01-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
J.Mol.Biol., 428, 2016
|
|
2Q0Z
 | | Crystal structure of Q9P172/Sec63 from Homo sapiens. Northeast Structural Genomics Target HR1979. | | 分子名称: | Protein PRO2281 | | 著者 | Benach, J, Neely, H, Abashidze, M, Edstrom, W.C, Seetharaman, J, Zhao, L, Fang, Y, Cunningham, K, Owens, L, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-05-23 | | 公開日 | 2007-06-05 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of Q9P172/Sec63 from Homo sapiens.
To be Published
|
|
6CUT
 | | Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine | | 分子名称: | (2S,3S)-3-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-methylpentanoic acid (non-preferred name), SODIUM ION, Tryptophan synthase beta chain 1 | | 著者 | Boville, C.E, Scheele, R.A, Buller, A.R, Arnold, F.H. | | 登録日 | 2018-03-26 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues.
Angew. Chem. Int. Ed. Engl., 57, 2018
|
|
4ZK7
 | | Crystal structure of rescued two-component self-assembling tetrahedral cage T33-31 | | 分子名称: | Chorismate mutase, Divalent-cation tolerance protein CutA | | 著者 | Liu, Y, Cascio, D, Sawaya, M.R, Bale, J, Collazo, M.J, Park, R, King, N, Baker, D, Yeates, T. | | 登録日 | 2015-04-30 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression.
Protein Sci., 24, 2015
|
|
4Z5W
 | | The plant peptide hormone receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Phytosulfokine, ... | | 著者 | Chai, J, Wang, J, Han, Z. | | 登録日 | 2015-04-03 | | 公開日 | 2016-03-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Allosteric receptor activation by the plant peptide hormone phytosulfokine
Nature, 525, 2015
|
|
4Z6D
 | |
4Z6L
 | | Structure of H200E variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum at 1.65 Ang resolution | | 分子名称: | CALCIUM ION, CHLORIDE ION, FE (II) ION, ... | | 著者 | Kovaleva, E.G, Lipscomb, J.D. | | 登録日 | 2015-04-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200.
Biochemistry, 54, 2015
|
|
6D0N
 | | Crystal structure of a CLC-type fluoride/proton antiporter, V319G mutant | | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | | 登録日 | 2018-04-10 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
|
|
4Z6Z
 | | Structure of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with 4-sulfonyl catechol at 1.52 Ang resolution | | 分子名称: | 3,4-dihydroxybenzenesulfonic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CALCIUM ION, ... | | 著者 | Kovaleva, E.G, Lipscomb, J.D. | | 登録日 | 2015-04-06 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structural Basis for Substrate and Oxygen Activation in Homoprotocatechuate 2,3-Dioxygenase: Roles of Conserved Active Site Histidine 200.
Biochemistry, 54, 2015
|
|
2PVF
 | |
2PVS
 | | Structure of human pancreatic lipase related protein 2 mutant N336Q | | 分子名称: | CALCIUM ION, Pancreatic lipase-related protein 2, SULFATE ION | | 著者 | Spinelli, S, Eydoux, C, Carriere, F, Cambillau, C. | | 登録日 | 2007-05-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.
Biochemistry, 47, 2008
|
|
6D1S
 | | Crystal structure of an apo chimeric human alpha1GABAA receptor | | 分子名称: | chimeric alpha1GABAA receptor | | 著者 | Chen, Q, Arjunan, P, Cohen, A.E, Xu, Y, Tang, P. | | 登録日 | 2018-04-12 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of neurosteroid anesthetic action on GABAAreceptors.
Nat Commun, 9, 2018
|
|
6CJ7
 | | Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12 | | 分子名称: | Serpin-12 | | 著者 | Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H. | | 登録日 | 2018-02-26 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph.
Insect Biochem. Mol. Biol., 99, 2018
|
|
4Z9V
 | | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL | | 分子名称: | BICARBONATE ION, Bcl-2-like protein 1,APOPTOSIS REGULATOR BCL-XL, SODIUM ION, ... | | 著者 | Cura, V, Agez, M, Thebault, S, Cavarelli, J. | | 登録日 | 2015-04-12 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.
Sci Rep, 6, 2016
|
|
4ZQK
 | | Structure of the complex of human programmed death-1 (PD-1) and its ligand PD-L1. | | 分子名称: | Programmed cell death 1 ligand 1, Programmed cell death protein 1, SODIUM ION | | 著者 | Zak, K.M, Dubin, G, Holak, T.A. | | 登録日 | 2015-05-10 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1.
Structure, 23, 2015
|
|
5VRN
 | | CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333. | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], [[(2~{R},3~{S},4~{R},5~{R})-5-(3-aminocarbonylpyridin-1-ium-1-yl)-4-[[5-[4-cyano-2-[(~{E})-hydroxyiminomethyl]phenoxy]-1-oxidanyl-3~{H}-2,1$l^{4}-benzoxaborol-1-yl]oxy]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Abendroth, J, Edwards, T.E, Lorimer, D. | | 登録日 | 2017-05-11 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA.
Life Sci Alliance, 1, 2018
|
|
6D1O
 | | FT_5 dioxygenase apoenzyme | | 分子名称: | (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase | | 著者 | Rydel, T.J, Halls, C.E. | | 登録日 | 2018-04-12 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
|
|
4YYT
 | | Human Carbonic Anhydrase II complexed with an inhibitor with a benzenesulfonamide group (5). | | 分子名称: | 4-(2-hydroxyethyl)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | | 著者 | Rechlin, C, Heine, A, Klebe, G. | | 登録日 | 2015-03-24 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | | 主引用文献 | Kinetic and Structural Insights into the Mechanism of Binding of Sulfonamides to Human Carbonic Anhydrase by Computational and Experimental Studies.
J.Med.Chem., 59, 2016
|
|
5VD3
 | |
4YZP
 | |
