3FDL
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![BU of 3fdl by Molmil](/molmil-images/mine/3fdl) | Bim BH3 peptide in complex with Bcl-xL | 分子名称: | Apoptosis regulator Bcl-X, Bcl-2-like protein 11 | 著者 | Fairlie, W.D, Lee, E.F, Smith, B.J, Czabotar, P.E, Colman, P.M. | 登録日 | 2008-11-26 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | High-Resolution Structural Characterization of a Helical alpha/beta-Peptide Foldamer Bound to the Anti-Apoptotic Protein Bcl-x(L) Angew.Chem.Int.Ed.Engl., 48, 2009
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7KJA
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5O90
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1F41
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![BU of 1f41 by Molmil](/molmil-images/mine/1f41) | CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN AT 1.5A RESOLUTION | 分子名称: | TRANSTHYRETIN | 著者 | Hornberg, A, Eneqvist, T, Olofsson, A, Lundgren, E, Sauer-Eriksson, A.E. | 登録日 | 2000-06-07 | 公開日 | 2000-09-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | A comparative analysis of 23 structures of the amyloidogenic protein transthyretin. J.Mol.Biol., 302, 2000
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5YCB
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5Y15
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![BU of 5y15 by Molmil](/molmil-images/mine/5y15) | Crystal structure of human DUSP28 | 分子名称: | Dual specificity phosphatase 28, PHOSPHATE ION | 著者 | Ku, B, Hong, W, Kim, S.J, Ryu, S.E. | 登録日 | 2017-07-19 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28 PLoS ONE, 12, 2017
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7KSM
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![BU of 7ksm by Molmil](/molmil-images/mine/7ksm) | Human mitochondrial LONP1 with endogenous substrate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Lon protease homolog, ... | 著者 | Shin, M, Watson, E.R, Song, A.S, Mindrebo, J.T, Novick, S.R, Griffin, P, Wiseman, R.L, Lander, G.C. | 登録日 | 2020-11-23 | 公開日 | 2020-12-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of the human LONP1 protease reveal regulatory steps involved in protease activation. Nat Commun, 12, 2021
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1F0Q
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![BU of 1f0q by Molmil](/molmil-images/mine/1f0q) | CRYSTAL STRUCTURE OF THE ALPHA SUBUNIT OF PROTEIN KINASE CK2 IN COMPLEX WITH THE NUCLEOTIDE COMPETITIVE INHIBITOR EMODIN | 分子名称: | 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, PROTEIN KINASE CK2, ALPHA SUBUNIT | 著者 | Battistutta, R, Sarno, S, De Moliner, E, Papinutto, E, Zanotti, G, Pinna, L.A. | 登録日 | 2000-05-17 | 公開日 | 2001-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2. J.Biol.Chem., 275, 2000
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1BI5
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![BU of 1bi5 by Molmil](/molmil-images/mine/1bi5) | CHALCONE SYNTHASE FROM ALFALFA | 分子名称: | CHALCONE SYNTHASE | 著者 | Ferrer, J.L, Jez, J.M, Bowman, M.E, Dixon, R.A, Noel, J.P. | 登録日 | 1998-06-22 | 公開日 | 1999-06-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat.Struct.Biol., 6, 1999
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1O2T
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![BU of 1o2t by Molmil](/molmil-images/mine/1o2t) | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | 分子名称: | 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-5-METHOXY-1,1'-BIPHENYL-2-OLATE, BETA-TRYPSIN, CALCIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. | 登録日 | 2003-03-06 | 公開日 | 2003-09-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease
inhibitors. J.Mol.Biol., 329, 2003
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3NW8
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![BU of 3nw8 by Molmil](/molmil-images/mine/3nw8) | Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, high-pH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | 登録日 | 2010-07-09 | 公開日 | 2010-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.75915 Å) | 主引用文献 | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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1O30
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![BU of 1o30 by Molmil](/molmil-images/mine/1o30) | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | 分子名称: | 2-(5-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-2'-FLUORO-6-OXIDO-1,1'-BIPHENYL-3-YL)SUCCINATE, BETA-TRYPSIN, CALCIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. | 登録日 | 2003-03-06 | 公開日 | 2003-09-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease
inhibitors. J.Mol.Biol., 329, 2003
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5EQC
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![BU of 5eqc by Molmil](/molmil-images/mine/5eqc) | Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... | 著者 | Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-11-12 | 公開日 | 2016-02-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site To Be Published
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1O3E
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![BU of 1o3e by Molmil](/molmil-images/mine/1o3e) | Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors | 分子名称: | 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIPHENYL-2-OLATE, BETA-TRYPSIN, CALCIUM ION, ... | 著者 | Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. | 登録日 | 2003-03-06 | 公開日 | 2003-09-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease
inhibitors. J.Mol.Biol., 329, 2003
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1RXL
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![BU of 1rxl by Molmil](/molmil-images/mine/1rxl) | Solution structure of the engineered protein Afae-dsc | 分子名称: | Afimbrial adhesin AFA-III | 著者 | Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, du Merle, L, Barlow, P.N, Medof, M.E, Smith, R.A, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S. | 登録日 | 2003-12-18 | 公開日 | 2005-01-11 | 最終更新日 | 2020-02-05 | 実験手法 | SOLUTION NMR | 主引用文献 | An atomic resolution model for assembly, architecture, and function of the Dr adhesins. Mol.Cell, 15, 2004
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1O86
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![BU of 1o86 by Molmil](/molmil-images/mine/1o86) | Crystal Structure of Human Angiotensin Converting Enzyme in complex with lisinopril. | 分子名称: | ANGIOTENSIN CONVERTING ENZYME, CHLORIDE ION, GLYCINE, ... | 著者 | Natesh, R, Schwager, S.L.U, Sturrock, E.D, Acharya, K.R. | 登録日 | 2002-11-25 | 公開日 | 2003-02-07 | 最終更新日 | 2013-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Human Angiotensin-Converting Enzyme-Lisinopril Complex Nature, 421, 2003
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4QE8
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![BU of 4qe8 by Molmil](/molmil-images/mine/4qe8) | FXR with DM175 and NCoA-2 peptide | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,2-ETHANEDIOL, 4-({2-[(4-tert-butylbenzoyl)amino]benzoyl}amino)benzoic acid, ... | 著者 | Kudlinzki, D, Merk, D, Linhard, V.L, Saxena, K, Sreeramulu, S, Nilsson, E, Dekker, N, Wissler, L, Bamberg, K, Schubert-Zsilavecz, M, Schwalbe, H. | 登録日 | 2014-05-15 | 公開日 | 2015-08-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | FXR with DM175 and NCoA-2 peptide To be Published
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6AJ8
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![BU of 6aj8 by Molmil](/molmil-images/mine/6aj8) | Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+, alpha-ketoglutarate and ca2+ | 分子名称: | 2-OXOGLUTARIC ACID, CALCIUM ION, Isocitrate dehydrogenase [NADP], ... | 著者 | Wang, X, Inaoka, D.K, Shiba, T, Balogun, E.O, Ziebart, N, Allman, S, Watanabe, Y, Nozaki, T, Boshart, M, Bringaud, F, Harada, S, Kita, K. | 登録日 | 2018-08-27 | 公開日 | 2019-08-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+) To Be Published
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1BIG
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![BU of 1big by Molmil](/molmil-images/mine/1big) | SCORPION TOXIN BMTX1 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES | 分子名称: | TOXIN BMTX1 | 著者 | Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H. | 登録日 | 1998-06-16 | 公開日 | 1999-01-13 | 最終更新日 | 2019-12-25 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels. Biochemistry, 37, 1998
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3S2G
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![BU of 3s2g by Molmil](/molmil-images/mine/3s2g) | Crystal Structure of FurX NADH+:Furfuryl alcohol I | 分子名称: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | 登録日 | 2011-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase To be Published
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1JKP
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![BU of 1jkp by Molmil](/molmil-images/mine/1jkp) | Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations | 分子名称: | 5'-D(*AP*TP*CP*TP*TP*CP*TP*CP*AP*AP*AP*AP*AP*C)-3', 5'-D(*TP*GP*TP*TP*TP*TP*TP*GP*AP*GP*AP*AP*GP*A)-3', DNA-INVERTASE HIN | 著者 | Chiu, T.K, Sohn, C, Johnson, R.C, Dickerson, R.E. | 登録日 | 2001-07-13 | 公開日 | 2002-02-22 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Testing water-mediated DNA recognition by the Hin recombinase. EMBO J., 21, 2002
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8DD1
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![BU of 8dd1 by Molmil](/molmil-images/mine/8dd1) | SARS-CoV-2 Main Protease (Mpro) H164N Mutant in Complex with Inhibitor GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase nsp5 | 著者 | Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. | 登録日 | 2022-06-17 | 公開日 | 2022-07-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir. Acs Cent.Sci., 9, 2023
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8DFN
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![BU of 8dfn by Molmil](/molmil-images/mine/8dfn) | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) H164N Mutant | 分子名称: | 3C-like proteinase nsp5 | 著者 | Lewandowski, E.M, Butler, S.G, Hu, Y, Tan, H, Wang, J, Chen, Y. | 登録日 | 2022-06-22 | 公開日 | 2022-07-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir. Acs Cent.Sci., 9, 2023
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6ALJ
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![BU of 6alj by Molmil](/molmil-images/mine/6alj) | ALDH1A2 liganded with NAD and compound WIN18,446 | 分子名称: | Aldehyde dehydrogenase 1A2, N,N'-(octane-1,8-diyl)bis(2,2-dichloroacetamide), NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Chen, Y, Zhu, J.-Y, Schonbrunn, E. | 登録日 | 2017-08-08 | 公開日 | 2018-01-10 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural Basis of ALDH1A2 Inhibition by Irreversible and Reversible Small Molecule Inhibitors. ACS Chem. Biol., 13, 2018
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4LEM
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![BU of 4lem by Molmil](/molmil-images/mine/4lem) | |