6AJ8

Crystal structure of Trypanosoma brucei glycosomal isocitrate dehydrogenase in complex with NADP+, alpha-ketoglutarate and ca2+

Summary for 6AJ8

• Entry DOI: 10.2210/pdb6aj8/pdb
• Descriptor: Isocitrate dehydrogenase [NADP], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: trypanosoma brucei, glycosome, metabolism, isocitrate dehydrogenase, oxidoreductase
• Biological source: Trypanosoma brucei brucei
• Total number of polymer chains: 2
• Total formula weight: 95296.24

Authors

Wang, X.,Inaoka, D.K.,Shiba, T.,Balogun, E.O.,Ziebart, N.,Allman, S.,Watanabe, Y.,Nozaki, T.,Boshart, M.,Bringaud, F.,Harada, S.,Kita, K. (deposition date: 2018-08-27, release date: 2019-08-28, Last modification date: 2023-11-22)

• Primary citation: Wang, X.,Inaoka, D.K.,Shiba, T.,Balogun, E.O.,Ziebart, N.,Allman, S.,Watanabe, Y.,Nozaki, T.,Boshart, M.,Bringaud, F.,Harada, S.,Kita, K.; Biochemical characterization of a novel Trypanosoma brucei glycosomal isocitrate dehydrogenase with dual coenzyme specificity (NADP+/NAD+); To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)