7D9Z
 
 | | Crystal structure of anti-basigin Fab fragment | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Heavy chain of antibody Fab fragment, ... | | 著者 | Sakuragi, T, Kanai, R, Narita, H, Onishi, E, Miyazaki, T, Baba, T, Nakagawa, A, Toyoshima, C, Nagata, S. | | 登録日 | 2020-10-14 | | 公開日 | 2021-10-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.123 Å) | | 主引用文献 | The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes.
Nat.Struct.Mol.Biol., 28, 2021
|
|
1NZM
 | | NMR structure of the parallel-stranded DNA quadruplex d(TTAGGGT)4 complexed with the telomerase inhibitor RHPS4 | | 分子名称: | 3,11-DIFLUORO-6,8,13-TRIMETHYL-8H-QUINO[4,3,2-KL]ACRIDIN-13-IUM, 5'-D(*TP*TP*AP*GP*GP*GP*T)-3', POTASSIUM ION | | 著者 | Gavathiotis, E, Heald, R.A, Stevens, M.F.G, Searle, M.S. | | 登録日 | 2003-02-18 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Drug Recognition and Stabilisation of the Parallel-stranded DNA Quadruplex d(TTAGGGT)4 Containing the Human Telomeric Repeat
J.Mol.Biol., 334, 2003
|
|
2YBG
 | | Structure of Lys120-acetylated p53 core domain | | 分子名称: | CELLULAR TUMOR ANTIGEN P53, ZINC ION | | 著者 | Arbely, E, Allen, M.D, Joerger, A.C, Fersht, A.R. | | 登録日 | 2011-03-08 | | 公開日 | 2011-05-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Acetylation of Lysine 120 of P53 Endows DNA- Binding Specificity at Effective Physiological Salt Concentration.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
1RF3
 | | Structurally Distinct Recognition Motifs in Lymphotoxin-B Receptor and CD40 for TRAF-mediated Signaling | | 分子名称: | 24-residue peptide from Lymphotoxin-B Receptor, TNF receptor associated factor 3 | | 著者 | Li, C, Norris, P.S, Ni, C.Z, Havert, M.L, Chiong, E.M, Tran, B.R, Cabezas, E, Cheng, G, Reed, J.C, Satterthwait, A.C, Ware, C.F, Ely, K.R. | | 登録日 | 2003-11-07 | | 公開日 | 2004-07-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.
J.Biol.Chem., 278, 2003
|
|
5EAV
 | | Unliganded structure of the ornithine aminotransferase from Toxoplasma gondii | | 分子名称: | DI(HYDROXYETHYL)ETHER, Ornithine aminotransferase, mitochondrial, ... | | 著者 | Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2015-10-16 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Unliganded structure of the ornithine aminotransferase from Toxoplasma gondii
To Be Published
|
|
3EH7
 | |
6A76
 | | Crystal structure of the Fab fragment of B5209B, a murine monoclonal antibody specific for the fifth immunoglobulin domain (Ig5) of human ROBO1 | | 分子名称: | GLYCEROL, Heavy chain of the anti-human Robo1 antibody B5209B Fab, Light chain of the anti-human Robo1 antibody B5209B Fab, ... | | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. | | 登録日 | 2018-07-02 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
|
|
4OJL
 | |
5OPU
 | | Structure of CHK1 10-pt. mutant complex with pyrrolopyridine LRRK2 inhibitor | | 分子名称: | 6-azanyl-4-(3-methylphenyl)-1~{H}-pyrrolo[2,3-b]pyridine-3-carbonitrile, CHLORIDE ION, Serine/threonine-protein kinase Chk1 | | 著者 | Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. | | 登録日 | 2017-08-10 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
J. Med. Chem., 60, 2017
|
|
4KNN
 | | Crystal structure of human carbonic anhydrase isozyme XIII with 2-Chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide | | 分子名称: | 1,2-ETHANEDIOL, 2-chloro-4-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide, ACETIC ACID, ... | | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | | 登録日 | 2013-05-10 | | 公開日 | 2013-11-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.404 Å) | | 主引用文献 | Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII
Bioorg.Med.Chem., 21, 2013
|
|
6S2N
 | |
1J08
 | | Crystal structure of glutaredoxin-like protein from Pyrococcus horikoshii | | 分子名称: | glutaredoxin-like protein | | 著者 | Tanaka, Y, Tanabe, E, Tsumoto, K, Kumagai, I, Yao, M, Tanaka, I. | | 登録日 | 2002-11-11 | | 公開日 | 2003-05-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Protein disulfide isomerase from hyperthermophile as an additives of refolding of an immunoglobulin-folded protein
To be Published
|
|
151D
 | | DIVERSITY OF WATER RING SIZE AT DNA INTERFACES: HYDRATION AND DYNAMICS OF DNA-ANTHRACYCLINE COMPLEXES | | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*G)-3'), DOXORUBICIN | | 著者 | Lipscomb, L.A, Peek, M.E, Zhou, F.X, Bertrand, J.A, VanDerveer, D, Williams, L.D. | | 登録日 | 1993-12-13 | | 公開日 | 1994-05-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Water ring structure at DNA interfaces: hydration and dynamics of DNA-anthracycline complexes.
Biochemistry, 33, 1994
|
|
1J7J
 | |
4DO8
 | | Crystal structure of the muscarinic toxin MT1 | | 分子名称: | ACETATE ION, Muscarinic toxin 1, THIOCYANATE ION | | 著者 | Fruchart-Gaillard, C, Mournier, G, Vera, L, Servent, D, Stura, E.A. | | 登録日 | 2012-02-09 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | Engineering of three-finger fold toxins creates ligands with original pharmacological profiles for muscarinic and adrenergic receptors.
Plos One, 7, 2012
|
|
6AF2
 | | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase | | 分子名称: | DI(HYDROXYETHYL)ETHER, HIT domain-containing protein, PENTAETHYLENE GLYCOL, ... | | 著者 | Mori, S, Honda, N, Kim, H, Rimbara, E, Shibayama, K. | | 登録日 | 2018-08-08 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Crystal structure of N-terminus deletion mutant of Mycobacterium avium diadenosine tetraphosphate phosphorylase
To Be Published
|
|
5X6I
 | | Crystal structure of B. subtilis adenylate kinase variant | | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ... | | 著者 | Moon, S, Bae, E. | | 登録日 | 2017-02-22 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and mutational analyses of psychrophilic and mesophilic adenylate kinases highlight the role of hydrophobic interactions in protein thermal stability.
Struct Dyn., 6, 2019
|
|
3S2F
 | | Crystal Structure of FurX NADH:Furfural | | 分子名称: | FURFURAL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHORYLISOPROPANE, ... | | 著者 | Hayes, R, Sanchez, E.J, Webb, B.N, Hooper, T, Nissen, M.S, Li, Q, Xun, L. | | 登録日 | 2011-05-16 | | 公開日 | 2012-06-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures and furfural reduction mechanism of a bacterial zinc-dependent alcohol dehydrogenase
To be Published
|
|
8CPD
 | | Cryo-EM structure of CRaf dimer with 14:3:3 | | 分子名称: | 14-3-3 protein zeta isoform X1, RAF proto-oncogene serine/threonine-protein kinase | | 著者 | Dedden, D, Graedler, U, Schwarz, D, Thomsen, M, Leuthner, B, Schneider, E, Nitsche, J. | | 登録日 | 2023-03-02 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes.
J.Mol.Biol., 436, 2024
|
|
3LTF
 | | Crystal Structure of the Drosophila Epidermal Growth Factor Receptor ectodomain in complex with Spitz | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | | 著者 | Alvarado, D, Klein, D.E, Lemmon, M.A. | | 登録日 | 2010-02-15 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for negative cooperativity in growth factor binding to an EGF receptor.
Cell(Cambridge,Mass.), 142, 2010
|
|
2FNE
 | | The crystal structure of the 13th PDZ domain of MPDZ | | 分子名称: | Multiple PDZ domain protein | | 著者 | Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-11 | | 公開日 | 2006-01-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
|
|
4KZ1
 | |
1AB6
 | | STRUCTURE OF CHEY MUTANT F14N, V86T | | 分子名称: | CHEMOTAXIS PROTEIN CHEY | | 著者 | Wilcock, D, Pisabarro, M.T, Lopez-Hernandez, E, Serranno, L, Coll, M. | | 登録日 | 1997-02-04 | | 公開日 | 1998-02-04 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure analysis of two CheY mutants: importance of the hydrogen-bond contribution to protein stability.
Acta Crystallogr.,Sect.D, 54, 1998
|
|
8C7D
 | | Structure of the GEF Kalirin DH2 Domain | | 分子名称: | Kalirin | | 著者 | Callens, M.C, Thompson, A.P, Gray, J.L, Bountra, C, von Delft, F, Brennan, P.E. | | 登録日 | 2023-01-14 | | 公開日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure-based alignment and analysis of RHO selectivity of RHO-DBL GTPase exchange factors
to be published
|
|
8BYL
 | | Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex | | 分子名称: | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ... | | 著者 | Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2022-12-13 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-07-19 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
|
|
