PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

---

4LYG	Crystal structure of human PRS1 E43T mutant 分子名称: Ribose-phosphate pyrophosphokinase 1, SULFATE ION 著者 Chen, P, Teng, M, Li, X. 登録日 2013-07-31 公開日 2015-02-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
4Z6F	Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE 分子名称: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(6OG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2015-04-04 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.444 Å) 主引用文献 Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta. Biochem. J., 475, 2018
4PUU	Human Aldose Reductase complexed with a ligand with an IDD structure (2-(2-carbamoyl-5-fluoro-phenoxy)acetic acid) at 1.14 A 分子名称: (2-carbamoyl-5-fluorophenoxy)acetic acid, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Rechlin, C, Heine, A, Klebe, G. 登録日 2014-03-14 公開日 2015-04-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Human Aldose Reductase: How expensive is the opening of the specificity pocket? IDD ligands under investigation To be Published
5X74	The crystal Structure PDE delta in complex with compound (R, R)-1g 分子名称: (2R)-2-(2-fluorophenyl)-3-[2-[4-[(2R)-2-(2-fluorophenyl)-4-oxidanylidene-1,2-dihydroquinazolin-3-yl]piperidin-1-yl]ethyl]-1,2-dihydroquinazolin-4-one, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta 著者 Jiang, Y, Zhuang, C, Chen, L, Wang, R, Wang, F, Sheng, C. 登録日 2017-02-23 公開日 2017-10-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural Biology-Inspired Discovery of Novel KRAS-PDE delta Inhibitors J. Med. Chem., 60, 2017
1X7H	Actinorhodin Polyketide Ketoreductase, with NADPH bound 分子名称: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketoacyl reductase 著者 Korman, T.P, Hill, J.A, Vu, T.N. 登録日 2004-08-13 公開日 2004-12-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural analysis of actinorhodin polyketide ketoreductase: cofactor binding and substrate specificity Biochemistry, 43, 2004
3SO6	Crystal structure of the LDL receptor tail in complex with autosomal recessive hypercholesterolemia PTB domain 分子名称: LDL receptor adaptor protein, Low-density lipoprotein receptor 著者 Dvir, H, Zajonc, D.M. 登録日 2011-06-29 公開日 2012-04-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail. Proc.Natl.Acad.Sci.USA, 109, 2012
6A8C	Ribokinase from Leishmania donovani with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Gatreddi, S, Vasudevan, D, Qureshi, I.A. 登録日 2018-07-06 公開日 2019-07-10 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Unraveling structural insights of ribokinase from Leishmania donovani. Int.J.Biol.Macromol., 136, 2019
4M6Y	Mutant structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid 分子名称: (2R)-2-hydroxy-3-phenylpropanoic acid, (3R)-2-oxo-3-phenylbutanoic acid, CALCIUM ION, ... 著者 Liu, Y.C, Zou, X.W, Chan, H.C, Huang, C.J, Li, T.L. 登録日 2013-08-12 公開日 2014-06-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and mechanism of a nonhaem-iron SAM-dependent C-methyltransferase and its engineering to a hydratase and an O-methyltransferase Acta Crystallogr.,Sect.D, 70, 2014
5X86	Crystal structure of TMP bound thymidylate kinase from thermus thermophilus HB8 分子名称: CHLORIDE ION, MAGNESIUM ION, THYMIDINE-5'-PHOSPHATE, ... 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2017-03-01 公開日 2018-03-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
4PPI	Crystal structure of Bcl-xL hexamer 分子名称: Bcl-2-like protein 1, GLYCEROL 著者 Sreekanth, R, Yoon, H.S. 登録日 2014-02-27 公開日 2015-03-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.851 Å) 主引用文献 Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport Sci Rep, 5, 2015
4ZC6	Crystal Structure of human GGT1 in complex with Serine Borate 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Gamma-glutamyltranspeptidase 1 heavy chain, ... 著者 Terzyan, S, Hanigan, M. 登録日 2015-04-15 公開日 2015-06-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human gamma-Glutamyl Transpeptidase 1: STRUCTURES OF THE FREE ENZYME, INHIBITOR-BOUND TETRAHEDRAL TRANSITION STATES, AND GLUTAMATE-BOUND ENZYME REVEAL NOVEL MOVEMENT WITHIN THE ACTIVE SITE DURING CATALYSIS. J.Biol.Chem., 290, 2015
5XAL	Y99F mutant of Thermus thermophilus HB8 thymidylate kinase 分子名称: FORMIC ACID, MAGNESIUM ION, Thymidylate kinase 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2017-03-14 公開日 2018-03-14 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
8SV1	Caspase-1 complex with interleukin-18 分子名称: Caspase-1, Interleukin-18 著者 Dong, Y, Pascal, D, Jon, K, Wu, H. 登録日 2023-05-15 公開日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Caspase-1 complex with interleukin-18 To Be Published
4ZKW	Crystal structure of the PmFTN variant E44Q soaked in iron (45 min) 分子名称: FE (III) ION, Ferritin 著者 Pfaffen, S, Murphy, M.E.P. 登録日 2015-04-30 公開日 2015-09-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Diatom Ferritin Optimized for Iron Oxidation but Not Iron Storage. J.Biol.Chem., 290, 2015
3S9T	Crystal structure of human carbonic anhydrase isozyme II with 2-chloro-5-{[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetyl}benzenesulfonamide 分子名称: 2-chloro-5-{[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetyl}benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Grazulis, S, Manakova, E, Tamulaitiene, G. 登録日 2011-06-02 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. Eur.J.Med.Chem., 51, 2012
5ZWY	Ribokinase from Leishmania donovani 分子名称: CHLORIDE ION, GLYCEROL, Ribokinase, ... 著者 Gatreddi, S, Vasudevan, D, Qureshi, I.A. 登録日 2018-05-17 公開日 2019-05-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Unraveling structural insights of ribokinase from Leishmania donovani. Int.J.Biol.Macromol., 136, 2019
4GLI	Crystal Structure of Human SMN YG-Dimer 分子名称: Maltose-binding periplasmic protein, Survival motor neuron protein chimera 著者 Martin, R.S, Perry, K, Van Duyne, G.D. 登録日 2012-08-14 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 The survival motor neuron protein forms soluble glycine zipper oligomers. Structure, 20, 2012
1XDW	NAD+-dependent (R)-2-Hydroxyglutarate Dehydrogenase from Acidaminococcus fermentans 分子名称: NAD+-dependent (R)-2-Hydroxyglutarate Dehydrogenase 著者 Martins, B.M, Macedo-Ribeiro, S, Bresser, J, Buckel, W, Messerschmidt, A. 登録日 2004-09-08 公開日 2005-03-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans. Febs J., 272, 2005
5XT8	Magnesium bound apo structure of thymidylate kinase (form I) from Thermus thermophilus HB8 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... 著者 Chaudhary, S.K, Jeyakanthan, J, Sekar, K. 登録日 2017-06-17 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and functional roles of dynamically correlated residues in thymidylate kinase. Acta Crystallogr D Struct Biol, 74, 2018
3SF8	Structural insights into thiol stabilization of DJ-1 分子名称: Protein DJ-1 著者 Premkumar, L, Dobaczewska, M.K, Riedl, S.J. 登録日 2011-06-13 公開日 2011-10-05 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1. J.Struct.Biol., 176, 2011
4GN1	Crystal Structure of the RA and PH domains of Lamellipodin 分子名称: MALONATE ION, Ras-associated and pleckstrin homology domains-containing protein 1 著者 Chang, Y.C.E, Wu, J. 登録日 2012-08-16 公開日 2012-11-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling. Protein Cell, 4, 2013
8CSV	Local refinement of Anykyrin-1 (N-terminal half of membrane binding domain) in Class 2 of erythrocyte ankyrin-1 complex 分子名称: Ankyrin-1, Band 3 anion transport protein 著者 Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B. 登録日 2022-05-13 公開日 2022-07-20 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Architecture of the human erythrocyte ankyrin-1 complex. Nat.Struct.Mol.Biol., 29, 2022
4M0K	Crystal structure of adenine phosphoribosyltransferase from Rhodothermus marinus DSM 4252, NYSGRC Target 029775. 分子名称: ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase, CALCIUM ION 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-08-01 公開日 2013-08-14 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of adenine phosphoribosyltransferase from Rhodothermus marinus DSM 4252, NYSGRC Target 029775. To be Published
4LZX	Complex of IQCG and Ca2+-free CaM 分子名称: Calmodulin, IQ domain-containing protein G, SULFATE ION 著者 Liang, W.X, Chen, L.T, Chen, Z, Chen, S.J, Chen, S. 登録日 2013-08-01 公開日 2014-05-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish Nat Commun, 5, 2014
4Q08	Crystal structure of chimeric carbonic anhydrase XII with inhibitor 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BICINE, ... 著者 Smirnov, A, Manakova, E, Grazulis, S. 登録日 2014-04-01 公開日 2015-01-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. J.Med.Chem., 57, 2014

<964965966967968969970971972973974975976977978979>