PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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5BKE	Crystal structure of AAD-2 in complex with Mn(II) and N-oxalylglycine 分子名称: Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, MANGANESE (II) ION, N-OXALYLGLYCINE, ... 著者 Chekan, J.R, Nair, S.K. 登録日 2019-06-02 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
6S6A	Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Anandapadamanaban, M, Masson, G.R, Perisic, O, Kaufman, J, Williams, R.L. 登録日 2019-07-02 公開日 2019-10-16 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366, 2019
3IID	Crystal structure of the macro domain of human histone macroH2A1.1 in complex with ADP-ribose (form A) 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Core histone macro-H2A.1, Isoform 1, ... 著者 Hothorn, M, Bortfeld, M, Ladurner, A.G, Scheffzek, K. 登録日 2009-07-31 公開日 2009-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat.Struct.Mol.Biol., 16, 2009
3PVB	Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase 分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S. 登録日 2010-12-06 公開日 2011-02-02 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase Structure, 19, 2011
6I0W	Human Carbonic Anhydrase II in complex with 4-Methoxybenzenesulfonamide 分子名称: 4-methoxybenzenesulfonamide, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2018-10-26 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Conformational Changes in Alkyl Chains Determine the Thermodynamic and Kinetic Binding Profiles of Carbonic Anhydrase Inhibitors. Acs Chem.Biol., 15, 2020
6RL9	Human Carbonic Anhydrase II in complex with 4-Aminobenzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Gloeckner, S, Heine, A, Klebe, G. 登録日 2019-05-01 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10, 2020
6HX5	Selenols: a new class of Carbonic Anhydrase inhibitors 分子名称: Carbonic anhydrase 2, ZINC ION, benzeneselenol 著者 Angeli, A, Ferraroni, M. 登録日 2018-10-16 公開日 2018-12-26 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Selenols: a new class of carbonic anhydrase inhibitors. Chem. Commun. (Camb.), 55, 2019
3T3T	1.38 A structure of human frataxin variant Q148G 分子名称: Frataxin, mitochondrial, SULFATE ION 著者 Bridwell-Rabb, J, Winn, A.M, Barondeau, D.P. 登録日 2011-07-25 公開日 2011-08-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Structure-Function Analysis of Friedreich's Ataxia Mutants Reveals Determinants of Frataxin Binding and Activation of the Fe-S Assembly Complex. Biochemistry, 50, 2011
1GOH	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: GALACTOSE OXIDASE, SODIUM ION 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
3T5Z	Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide 分子名称: Carbonic anhydrase 2, MERCURIBENZOIC ACID, N-methoxybenzenesulfonamide, ... 著者 Di Fiore, A, Maresca, A, Alterio, V, Supuran, C.T, De Simone, G. 登録日 2011-07-28 公開日 2012-06-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem.Commun.(Camb.), 47, 2011
1Q8H	Crystal structure of porcine osteocalcin 分子名称: CALCIUM ION, Osteocalcin 著者 Hoang, Q.Q, Sicheri, F, Howard, A.J, Yang, D.S. 登録日 2003-08-21 公開日 2003-11-11 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Bone recognition mechanism of porcine osteocalcin from crystal structure. Nature, 425, 2003
6HH0	Yeast V-ATPase transmembrane helix 7 NMR structure in DPC micelles 分子名称: V-type proton ATPase subunit a, vacuolar isoform 著者 Zangger, K, Hohlweg, W, Wagner, G. 登録日 2018-08-24 公開日 2018-09-12 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 A cation-pi interaction in a transmembrane helix of vacuolar ATPase retains the proton-transporting arginine in a hydrophobic environment. J. Biol. Chem., 293, 2018
3T4P	Crystal structure of O-Acetyl Serine Sulfhydrylase from Leishmania donovani in complex with designed tetrapeptide 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, O-acetyl serine sulfhydrylase, ... 著者 Raj, I, Gourinath, S. 登録日 2011-07-26 公開日 2012-08-01 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The narrow active-site cleft of O-acetylserine sulfhydrylase from Leishmania donovani allows complex formation with serine acetyltransferases with a range of C-terminal sequences Acta Crystallogr.,Sect.D, 68, 2012
1Q9C	Crystal Structure of the Histone domain of Son of Sevenless 分子名称: Son of sevenless protein 著者 Sondermann, H, Soisson, S.M, Bar-Sagi, D, Kuriyan, J. 登録日 2003-08-24 公開日 2003-12-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Tandem Histone Folds in the Structure of the N-terminal Segment of the Ras Activator Son of Sevenless Structure, 11, 2003
6RMX	Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide 分子名称: 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Smirnov, A, Paketuryte, V, Manakova, E, Grazulis, S. 登録日 2019-05-07 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide To Be Published
2ERJ	Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Debler, E.W, Stauber, D.J, Wilson, I.A. 登録日 2005-10-25 公開日 2006-02-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor. Proc.Natl.Acad.Sci.Usa, 103, 2006
1QAB	The structure of human retinol binding protein with its carrier protein transthyretin reveals interaction with the carboxy terminus of RBP 分子名称: PROTEIN (retinol binding protein), PROTEIN (transthyretin), RETINOL 著者 Naylor, H.M, Newcomer, M.E. 登録日 1999-02-03 公開日 1999-02-16 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP. Biochemistry, 38, 1999
3T83	Human Carbonic Anhydrase II in complex with Acetylated Carbohydrate Sulfamates 分子名称: 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-alpha-D-glucopyranose, 2,3,4-tri-O-propanoyl-6-O-sulfamoyl-beta-D-glucopyranose, Carbonic anhydrase 2, ... 著者 Hofmann, A, Wang, C.K. 登録日 2011-08-01 公開日 2011-10-19 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Promiscuity of carbonic anhydrase II. Unexpected ester hydrolysis of carbohydrate-based sulfamate inhibitors. J.Am.Chem.Soc., 133, 2011
4IE4	Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with 5-carboxy-8-hydroxyquinoline (IOX1) 分子名称: 8-hydroxyquinoline-5-carboxylic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, GLYCEROL, ... 著者 Aik, W.S, McDonough, M.A, Schofield, C.J. 登録日 2012-12-13 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5048 Å) 主引用文献 Structural basis for inhibition of the fat mass and obesity associated protein (FTO) J.Med.Chem., 56, 2013
8E0B	Crystal structure of human Sar1bT39N 分子名称: GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Sar1bT39N 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.212 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
8E0C	Crystal structure of human Sar1bH79G 分子名称: GTP-binding protein SAR1b, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Huang, Q. 登録日 2022-08-08 公開日 2023-08-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.993 Å) 主引用文献 The alarmone ppGpp selectively inhibits the isoform A of the human small GTPase Sar1. Proteins, 91, 2023
3LBO	Human aldose reductase mutant T113C complexed with IDD594 分子名称: Aldose reductase, BROMIDE ION, CITRIC ACID, ... 著者 Koch, C, Heine, A, Klebe, G. 登録日 2010-01-08 公開日 2010-12-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Tracing the detail: how mutations affect binding modes and thermodynamic signatures of closely related aldose reductase inhibitors J.Mol.Biol., 406, 2011
1GOF	NOVEL THIOETHER BOND REVEALED BY A 1.7 ANGSTROMS CRYSTAL STRUCTURE OF GALACTOSE OXIDASE 分子名称: ACETIC ACID, COPPER (II) ION, GALACTOSE OXIDASE, ... 著者 Ito, N, Phillips, S.E.V, Knowles, P.F. 登録日 1993-09-30 公開日 1994-01-31 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Novel thioether bond revealed by a 1.7 A crystal structure of galactose oxidase. Nature, 350, 1991
4AHG	S28N - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis 分子名称: ANGIOGENIN, D(-)-TARTARIC ACID 著者 Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. 登録日 2012-02-06 公開日 2012-10-10 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.448 Å) 主引用文献 Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
5BK9	AAD-1 Bound to the Vanadyl Ion and Succinate 分子名称: (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, PHOSPHATE ION, SUCCINIC ACID, ... 著者 Ongpipattanakul, C, Chekan, J.R. 登録日 2019-06-01 公開日 2019-06-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019

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