6S6A

Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex

Summary for 6S6A

Entry DOI	10.2210/pdb6s6a/pdb
Descriptor	Ras-related GTP-binding protein A, Ras-related GTP-binding protein C, GUANOSINE-5'-TRIPHOSPHATE, ... (7 entities in total)
Functional Keywords	small gtpases, mtorc1 activator, roadblock domain, gtpase domain, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	164063.87
Authors	Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Kaufman, J.,Williams, R.L. (deposition date: 2019-07-02, release date: 2019-10-16, Last modification date: 2019-10-23)
Primary citation	Anandapadamanaban, M.,Masson, G.R.,Perisic, O.,Berndt, A.,Kaufman, J.,Johnson, C.M.,Santhanam, B.,Rogala, K.B.,Sabatini, D.M.,Williams, R.L. Architecture of human Rag GTPase heterodimers and their complex with mTORC1. Science, 366:203-210, 2019 Cited by PubMed: 31601764 DOI: 10.1126/science.aax3939 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.63 Å)

Structure validation