6S6A
Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ras-related GTP-binding protein A | polymer | 313 | 36600.2 | 2 | UniProt (Q7L523) Pfam (PF04670) | Homo sapiens (Human) | RagA,Adenovirus E3 14.7 kDa-interacting protein 1,FIP-1 |
| 2 | C, D (C, D) | Ras-related GTP-binding protein C | polymer | 399 | 44284.8 | 2 | UniProt (Q9HB90) Pfam (PF04670) | Homo sapiens (Human) | RagC,GTPase-interacting protein 2,TIB929 |
| 3 | E, H (A, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) | Homo sapiens | ||
| 4 | F, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, J, K (A, B) | pentane-1,5-diol | non-polymer | 104.1 | 3 | Chemie (9JE) | |||
| 6 | L, M (C, D) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 7 | N, O, P, Q (A, B, C, D) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 313 (UniProt: Q7L523)
C, D: 1 - 399 (UniProt: Q9HB90)
| PDB | External Database | Details |
|---|---|---|
| Leu 66 | Gln 66 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Asn 90 | Thr 90 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 161770.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2293.8 | |
| All* | Total formula weight | 164063.9 |
