PDB: 184427 件ウェブページステータス検索Chemie searchBIRD

---

8BO3	COAGULATION FACTOR XI PROTEASE DOMAIN IN COMPLEX WITH ACTIVE SITE INHIBITOR Asundexian 分子名称: 4-[[(2~{S})-2-[4-[5-chloranyl-2-[4-(trifluoromethyl)-1,2,3-triazol-1-yl]phenyl]-5-methoxy-2-oxidanylidene-pyridin-1-yl]butanoyl]amino]-2-fluoranyl-benzamide, CITRIC ACID, Coagulation factor XIa light chain 著者 Schaefer, M, Roehrig, S, Ackerstaff, J, Nunez, E.J, Gericke, K.M, Meier, K, Tersteegen, A, Stampfuss, J, Ellerbrock, P, Meibom, D, Lang, D, Heitmeier, S, Hillisch, A. 登録日 2022-11-14 公開日 2023-09-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.841 Å) 主引用文献 Design and Preclinical Characterization Program toward Asundexian (BAY 2433334), an Oral Factor XIa Inhibitor for the Prevention and Treatment of Thromboembolic Disorders. J.Med.Chem., 66, 2023
1QUS	1.7 A RESOLUTION STRUCTURE OF THE SOLUBLE LYTIC TRANSGLYCOSYLASE SLT35 FROM ESCHERICHIA COLI 分子名称: 1,2-ETHANEDIOL, BICINE, LYTIC MUREIN TRANSGLYCOSYLASE B, ... 著者 van Asselt, E.J, Dijkstra, A.J, Kalk, K.H, Takacs, B, Keck, W, Dijkstra, B.W. 登録日 1999-07-03 公開日 1999-09-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Escherichia coli lytic transglycosylase Slt35 reveals a lysozyme-like catalytic domain with an EF-hand. Structure Fold.Des., 7, 1999
1CKS	HUMAN CKSHS2 ATOMIC STRUCTURE: A ROLE FOR ITS HEXAMERIC ASSEMBLY IN CELL CYCLE CONTROL 分子名称: CYCLIN-DEPENDENT KINASE SUBUNIT, TYPE 2, SULFATE ION 著者 Parge, H.E, Arvai, A.S, Tainer, J.A. 登録日 1993-09-16 公開日 1995-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control. Science, 262, 1993
1HWR	MOLECULAR RECOGNITION OF CYCLIC UREA HIV PROTEASE INHIBITORS 分子名称: HIV-1 PROTEASE, [4-R-(4-ALPHA,6-BETA,7-BETA]-HEXAHYDRO-5,6-DI(HYDROXY)-1,3-DI(ALLYL)-4,7-BISPHENYLMETHYL)-2H-1,3-DIAZEPINONE 著者 Chang, C.-H. 登録日 1998-03-20 公開日 1999-03-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Molecular recognition of cyclic urea HIV-1 protease inhibitors. J.Biol.Chem., 273, 1998
4O8N	Crystal structure of SthAraf62A, a GH62 family alpha-L-arabinofuranosidase from Streptomyces thermoviolaceus, in the apoprotein form 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alpha-L-arabinofuranosidase, CALCIUM ION, ... 著者 Stogios, P.J, Wang, W, Xu, X, Cui, H, Master, E, Savchenko, A. 登録日 2013-12-28 公開日 2014-07-02 最終更新日 2022-08-24 実験手法 X-RAY DIFFRACTION (1.6476 Å) 主引用文献 Elucidation of the molecular basis for arabinoxylan-debranching activity of a thermostable family GH62 alpha-l-arabinofuranosidase from Streptomyces thermoviolaceus. Appl.Environ.Microbiol., 80, 2014
4JZJ	Crystal Structure of Receptor-Fab Complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy Chain, Fab Light Chain, ... 著者 Broughton, S.E, Parker, M.W. 登録日 2013-04-03 公開日 2014-04-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody Cell Rep, 8, 2014
5CYA	Crystal structure of Arl2 GTPase-activating protein tubulin cofactor C (TBCC) 分子名称: SULFATE ION, Tubulin-specific chaperone C 著者 Nithianantham, S, Le, S, Seto, E, Jia, W, Leary, J, Corbett, K.D, Moore, J.K, Al-Bassam, J. 登録日 2015-07-30 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble alpha beta-tubulin pool for microtubule dynamics. Elife, 4, 2015
7UCC	Transcription factor FosB/JunD bZIP domain in the reduced form 分子名称: CHLORIDE ION, ETHANOL, Protein fosB, ... 著者 Kumar, A, Machius, M.C, Rudenko, G. 登録日 2022-03-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Chemically targeting the redox switch in AP1 transcription factor Delta FOSB. Nucleic Acids Res., 50, 2022
5CYS	Structure of the enzyme-product complex resulting from TDG action on a GcaC mismatch 分子名称: ACETIC ACID, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase 著者 Pozharski, E, Malik, S.S, Drohat, A.C. 登録日 2015-07-30 公開日 2015-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Characterizing the enzyme-product complexes of thymine DNA glycosylase using crystallography and NMR Nucleic Acids Res., 2015
7UCD	Transcription factor FosB/JunD bZIP domain covalently modified with the cysteine-targeting alpha-haloketone compound Z2159931480 分子名称: 7-acetyl-4-methoxy-1-benzofuran-3(2H)-one, CHLORIDE ION, Protein fosB, ... 著者 Kumar, A, Machius, M.C, Rudenko, G. 登録日 2022-03-16 公開日 2023-01-25 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Chemically targeting the redox switch in AP1 transcription factor Delta FOSB. Nucleic Acids Res., 50, 2022
1HKB	CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE 分子名称: 6-O-phosphono-alpha-D-glucopyranose, CALCIUM ION, D-GLUCOSE 6-PHOSPHOTRANSFERASE, ... 著者 Aleshin, A.E, Zeng, C, Burenkov, G.P, Bartunik, H.D, Fromm, H.J, Honzatko, R.B. 登録日 1997-12-01 公開日 1998-06-03 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate. Structure, 6, 1998
1QZ1	Crystal Structure of the Ig 1-2-3 fragment of NCAM 分子名称: Neural cell adhesion molecule 1, 140 kDa isoform 著者 Soroka, V, Kolkova, K, Kastrup, J.S, Diederichs, K, Breed, J, Kiselyov, V.V, Poulsen, F.M, Larsen, I.K, Welte, W, Berezin, V, Bock, E, Kasper, C. 登録日 2003-09-15 公開日 2003-11-04 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and interactions of NCAM Ig1-2-3 suggest a novel zipper mechanism for homophilic adhesion Structure, 11, 2003
5X31	Pseudoazurin from Alcaligenes faecalis (space group P65) 分子名称: COPPER (II) ION, Pseudoazurin 著者 Fukuda, Y, Mizohata, E, Inoue, T. 登録日 2017-02-03 公開日 2017-04-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 New molecular packing in a crystal of pseudoazurin from Alcaligenes faecalis: a double-helical arrangement of blue copper Acta Crystallogr F Struct Biol Commun, 73, 2017
5D43	crystal structrue of Mouse centrin 1 in calcium-saturated form 分子名称: CALCIUM ION, Centrin-1 著者 Park, J.H, Kim, S.Y, Kim, D.S. 登録日 2015-08-07 公開日 2016-09-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Crystal Structure of Wild-Type Centrin 1 from Mus musculus Occupied by Ca2. Biochemistry Mosc., 82, 2017
3LEE	Crystal structure of the human squalene synthase complexed with BPH-652 分子名称: (1R)-4-(3-phenoxyphenyl)-1-phosphonobutane-1-sulfonic acid, MAGNESIUM ION, Squalene synthetase 著者 Liu, Y.-L, Lin, F.-Y, Oldfield, E. 登録日 2010-01-14 公開日 2010-12-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Mechanism of Action (and Inhibition) of Head-to-Head Terpene Synthases: A Structural Investigation To be Published
1R0Q	Characterization of the conversion of the malformed, recombinant cytochrome rc552 to a 2-formyl-4-vinyl (Spirographis) heme 分子名称: 2-FORMYL-PROTOPORPHRYN IX, Cytochrome c-552 著者 Fee, J.A, Todaro, T.R, Luna, E, Sanders, D, Hunsicker-Wang, L.M, Patel, K.M, Bren, K.L, Gomez-Moran, E, Hill, M.G, Ai, J, Loehr, T.M, Oertling, W.A, Williams, P.A, Stout, C.D, McRee, D, Pastuszyn, A. 登録日 2003-09-22 公開日 2004-09-28 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Cytochrome rC552, formed during expression of the truncated, Thermus thermophilus cytochrome c552 gene in the cytoplasm of Escherichia coli, reacts spontaneously to form protein-bound 2-formyl-4-vinyl (Spirographis) heme. Biochemistry, 43, 2004
5XF8	Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state 分子名称: Cell division cycle protein CDT1, DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, ... 著者 Zhai, Y, Cheng, E, Wu, H, Li, N, Yung, P.Y, Gao, N, Tye, B.K. 登録日 2017-04-09 公開日 2017-05-03 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer Nat. Struct. Mol. Biol., 24, 2017
4ONK	[Leu-5]-Enkephalin mutant - YVVFL 分子名称: [Leu-5]-Enkephalin mutant - YVVFL 著者 Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C. 登録日 2014-01-28 公開日 2014-07-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J.Phys.Chem.B, 118, 2014
1HOS	INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-1 PROTEASE BY A C2-SYMMETRIC PHOSPHINATE SYNTHESIS AND CRYSTALLOGRAPHIC ANALYSIS 分子名称: (2-PHENYL-1-CARBOBENZYL-OXYVALYL-AMINO)-ETHYL-PHOSPHINIC ACID, HIV-1 PROTEASE 著者 Abdel-Meguid, S, Zhao, B. 登録日 1993-04-06 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis. Biochemistry, 32, 1993
4KGA	Crystal structure of kallikrein-related peptidase 4 分子名称: 1,2-ETHANEDIOL, Kallikrein-4, NICKEL (II) ION 著者 Ilyichova, O.V, Swedberg, J.E, de Veer, S.J, Sit, K.C, Harris, J.M, Buckle, A.M. 登録日 2013-04-29 公開日 2014-04-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics Sci Rep, 6, 2016
4OXB	Structure of ECP with sulphate anions at 1.50 Angstroms 分子名称: Eosinophil cationic protein, SULFATE ION 著者 Blanco, J.A, Boix, E, Moussaoui, M. 登録日 2014-02-05 公開日 2015-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of ECP at 1.50 with sulphate anions at 1.50 Angstroms To be published
1HWJ	COMPLEX OF THE CATALYTIC PORTION OF HUMAN HMG-COA REDUCTASE WITH CERIVASTATIN 分子名称: 7-[4-(4-FLUORO-PHENYL)-5-HYDROXYMETHYL-2,6-DIISOPROPYL-PYRIDIN-3-YL]-3,5-DIHYDROXY-HEPTANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, HMG-COA REDUCTASE 著者 Istvan, E.S, Deisenhofer, J. 登録日 2001-01-09 公開日 2001-05-11 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structural mechanism for statin inhibition of HMG-CoA reductase. Science, 292, 2001
5X9S	Crystal structure of fully modified H-Ras-GppNHp 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Matsumoto, S, Ke, H, Murashima, Y, Taniguchi-Tamura, H, Miyamoto, R, Yoshikawa, Y, Kumasaka, T, Mizohata, E, Edamatsu, H, Kataoka, T. 登録日 2017-03-09 公開日 2017-08-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for intramolecular interaction of post-translationally modified H-RasGTP prepared by protein ligation FEBS Lett., 591, 2017
3DNB	HELIX GEOMETRY, HYDRATION, AND G.A MISMATCH IN A B-DNA DECAMER 分子名称: DNA (5'-D(*CP*CP*AP*AP*GP*AP*TP*TP*GP*G)-3'), MAGNESIUM ION 著者 Prive, G.G, Dickerson, R.E. 登録日 1988-03-18 公開日 1989-01-09 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of the B-DNA decamer C-C-A-A-C-G-T-T-G-G and comparison with isomorphous decamers C-C-A-A-G-A-T-T-G-G and C-C-A-G-G-C-C-T-G-G. J.Mol.Biol., 217, 1991
5DJ9	Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, ... 著者 Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2015-09-01 公開日 2016-10-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with gabaculine To Be Published

<961962963964965966967968969970971972973974975976>