1DY5
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![BU of 1dy5 by Molmil](/molmil-images/mine/1dy5) | Deamidated derivative of bovine pancreatic ribonuclease | 分子名称: | ACETATE ION, ISOPROPYL ALCOHOL, RIBONUCLEASE A, ... | 著者 | Esposito, L, Vitagliano, L, Sica, F, Zagari, A, Mazzarella, L. | 登録日 | 2000-01-27 | 公開日 | 2000-03-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (0.87 Å) | 主引用文献 | The Ultrahigh Resolution Crystal Structure of Ribonuclease A Containing an Isoaspartyl Residue: Hydration and Sterochemical Analysis. J.Mol.Biol., 297, 2000
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5WBP
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5WBR
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![BU of 5wbr by Molmil](/molmil-images/mine/5wbr) | Structure of human Ketohexokinase complexed with hits from fragment screening | 分子名称: | 6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-[(3S)-3-(hydroxymethyl)piperidin-1-yl]-4-(trifluoromethyl)pyridine-3-carbonitrile, CITRIC ACID, GLYCEROL, ... | 著者 | Pandit, J. | 登録日 | 2017-06-29 | 公開日 | 2017-09-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J. Med. Chem., 60, 2017
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4TVP
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![BU of 4tvp by Molmil](/molmil-images/mine/4tvp) | Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level Definition of Pre-Fusion gp120 and gp41, in Complex with Human Antibodies PGT122 and 35O22 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... | 著者 | Pancera, M, Zhou, T, Kwong, P.D. | 登録日 | 2014-06-27 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature, 514, 2014
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4KCT
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![BU of 4kct by Molmil](/molmil-images/mine/4kct) | Pyruvate kinase (PYK) from Trypanosoma brucei soaked with Oxaloacetate | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... | 著者 | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2013-04-24 | 公開日 | 2014-01-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Pyruvate kinases have an intrinsic and conserved decarboxylase activity. Biochem.J., 458, 2014
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4KCV
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![BU of 4kcv by Molmil](/molmil-images/mine/4kcv) | Pyruvate kinase (PYK) from Trypanosoma brucei soaked with 2-oxoglutaric acid | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, 2-OXOGLUTARIC ACID, GLYCEROL, ... | 著者 | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2013-04-24 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Pyruvate kinases have an intrinsic and conserved decarboxylase activity. Biochem.J., 458, 2014
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6QMH
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6QMI
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4KCW
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![BU of 4kcw by Molmil](/molmil-images/mine/4kcw) | Pyruvate kinase (PYK) from Trypanosoma brucei soaked with oxalate | 分子名称: | 2,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ... | 著者 | Zhong, W, Morgan, H.P, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | 登録日 | 2013-04-24 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Pyruvate kinases have an intrinsic and conserved decarboxylase activity. Biochem.J., 458, 2014
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2NNR
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![BU of 2nnr by Molmil](/molmil-images/mine/2nnr) | Crystal structure of chagasin, cysteine protease inhibitor from Trypanosoma cruzi | 分子名称: | CHLORIDE ION, Chagasin, GLYCEROL, ... | 著者 | Redzynia, I, Bujacz, G, Ljunggren, A, Jaskolski, M, Abrahamson, M. | 登録日 | 2006-10-24 | 公開日 | 2007-07-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the parasite protease inhibitor chagasin in complex with a host target cysteine protease J.Mol.Biol., 371, 2007
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5GHX
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![BU of 5ghx by Molmil](/molmil-images/mine/5ghx) | Crystal structure of beta-lactamase PenP mutant-E166H | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, Beta-lactamase | 著者 | Pan, X, Zhao, Y. | 登録日 | 2016-06-21 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Crystallographic Snapshots of Class A beta-Lactamase Catalysis Reveal Structural Changes That Facilitate beta-Lactam Hydrolysis J. Biol. Chem., 292, 2017
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4IFL
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![BU of 4ifl by Molmil](/molmil-images/mine/4ifl) | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes | 分子名称: | Nrf2 peptide, kelch-like ECH-associated protein 1 | 著者 | Pan, H, Lin, M, Yang, Y, Callaway, K, Baker, J, Diep, L, Yan, J, Tanaka, K, Zhu, Y.L, Konradi, A.W, Jobling, M, Tam, D, Ren, Z, Cheung, H, Bova, M, Riley, B.E, Yao, N, Artis, D.R. | 登録日 | 2012-12-14 | 公開日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes Acta Crystallogr.,Sect.D
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5GHY
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5GHZ
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4KLB
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![BU of 4klb by Molmil](/molmil-images/mine/4klb) | Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176 | 分子名称: | 2-{[(1H-1,2,4-triazol-5-ylsulfanyl)acetyl]amino}thiophene-3-carboxamide, Cruzipain | 著者 | Fernandes, W.B, Montanari, C.A, Mckerrow, J.H. | 登録日 | 2013-05-07 | 公開日 | 2013-09-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay. Plos Negl Trop Dis, 7, 2013
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5KWL
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![BU of 5kwl by Molmil](/molmil-images/mine/5kwl) | expanded poliovirus in complex with VHH 10E | 分子名称: | VHH 10E, VP1, VP2, ... | 著者 | Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M. | 登録日 | 2016-07-18 | 公開日 | 2016-11-02 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State. J. Virol., 91, 2017
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6QMG
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4IFN
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![BU of 4ifn by Molmil](/molmil-images/mine/4ifn) | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes | 分子名称: | (1R,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid, kelch-like ECH-associated protein 1 | 著者 | Pan, H, Lin, M, Yang, Y, Callaway, K, Baker, J, Diep, L, Yan, J, Tanaka, K, Zhu, Y.L, Konradi, A.W, Jobling, M, Tam, D, Ren, Z, Cheung, H, Bova, M, Riley, B.E, Yao, N, Artis, D.R. | 登録日 | 2012-12-14 | 公開日 | 2013-12-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes Acta Crystallogr.,Sect.D
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4IFJ
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![BU of 4ifj by Molmil](/molmil-images/mine/4ifj) | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes | 分子名称: | Kelch-like ECH-associated protein 1 | 著者 | Pan, H, Lin, M, Yang, Y, Callaway, K, Baker, J, Diep, L, Yan, J, Tanaka, K, Zhu, Y.L, Konradi, A.W, Jobling, M, Tam, D, Ren, Z, Cheung, H, Bova, M, Riley, B.E, Yao, N, Artis, D.R. | 登録日 | 2012-12-14 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes To be Published
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4JHR
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![BU of 4jhr by Molmil](/molmil-images/mine/4jhr) | An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs | 分子名称: | G-protein-signaling modulator 2 | 著者 | Pan, Z, Zhu, J, Shang, Y, Wei, Z, Jia, M, Xia, C, Wen, W, Wang, W, Zhang, M. | 登録日 | 2013-03-05 | 公開日 | 2013-06-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An autoinhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and TPR motifs Structure, 21, 2013
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1EDQ
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5KU2
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![BU of 5ku2 by Molmil](/molmil-images/mine/5ku2) | expanded poliovirus in complex with VHH 7A | 分子名称: | VHH 7A, VP1, VP2, ... | 著者 | Strauss, M, Schotte, L, Filman, D.J, Hogle, J.M. | 登録日 | 2016-07-12 | 公開日 | 2016-11-02 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State. J. Virol., 91, 2017
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5WBO
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4MRT
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![BU of 4mrt by Molmil](/molmil-images/mine/4mrt) | Structure of the Phosphopantetheine Transferase Sfp in Complex with Coenzyme A and a Peptidyl Carrier Protein | 分子名称: | 4'-phosphopantetheinyl transferase sfp, COENZYME A, GLYCEROL, ... | 著者 | Tufar, P, Rahighi, S, Kraas, F.I, Kirchner, D.K, Loehr, F, Henrich, E, Koepke, J, Dikic, I, Guentert, P, Marahiel, M.A, Doetsch, V. | 登録日 | 2013-09-17 | 公開日 | 2014-04-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a PCP/Sfp Complex Reveals the Structural Basis for Carrier Protein Posttranslational Modification. Chem.Biol., 21, 2014
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5ZDQ
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![BU of 5zdq by Molmil](/molmil-images/mine/5zdq) | Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with COLLETOCHLORIN B | 分子名称: | 3-chloro-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-4,6-dihydroxy-2-methylbenzaldehyde, Alternative oxidase, mitochondrial, ... | 著者 | Shiba, T, Inaoka, D.K, Takahashi, G, Tsuge, C, Kido, Y, Young, L, Ueda, S, Balogun, E.O, Nara, T, Honma, T, Tanaka, A, Inoue, M, Saimoto, H, Harada, S, Moore, A.L, Kita, K. | 登録日 | 2018-02-23 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insights into the ubiquinol/dioxygen binding and proton relay pathways of the alternative oxidase. Biochim Biophys Acta Bioenerg, 1860, 2019
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