4IFN

Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes

Summary for 4IFN

• Entry DOI: 10.2210/pdb4ifn/pdb
• Related: 4IFJ 4IFL
• Descriptor: kelch-like ECH-associated protein 1, (1R,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid (3 entities in total)
• Functional Keywords: protein binding, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q14145
• Total number of polymer chains: 1
• Total formula weight: 32275.02

Authors

Pan, H.,Lin, M.,Yang, Y.,Callaway, K.,Baker, J.,Diep, L.,Yan, J.,Tanaka, K.,Zhu, Y.L.,Konradi, A.W.,Jobling, M.,Tam, D.,Ren, Z.,Cheung, H.,Bova, M.,Riley, B.E.,Yao, N.,Artis, D.R. (deposition date: 2012-12-14, release date: 2013-12-18)

• Primary citation: Pan, H.,Lin, M.,Yang, Y.,Callaway, K.,Baker, J.,Diep, L.,Yan, J.,Tanaka, K.,Zhu, Y.L.,Konradi, A.W.,Jobling, M.,Tam, D.,Ren, Z.,Cheung, H.,Bova, M.,Riley, B.E.,Yao, N.,Artis, D.R.; Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes; Acta Crystallogr.,Sect.D,

Experimental method

X-RAY DIFFRACTION (2.4 Å)