4IFN
Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | kelch-like ECH-associated protein 1 | polymer | 291 | 31828.5 | 1 | UniProt (Q14145) Pfam (PF01344) In PDB | Homo sapiens (human) | |
| 2 | X | (1R,2R)-2-{[(1S)-1-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-3,4-dihydroisoquinolin-2(1H)-yl]carbonyl}cyclohexanecarboxylic acid | non-polymer | 446.5 | 1 | Chemie (12O) | |||
| 3 | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
X: 321 - 609 (UniProt: Q14145)
| PDB | External Database | Details |
|---|---|---|
| Ser 319 | - | EXPRESSION TAG |
| Ser 320 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31828.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 446.5 | |
| All* | Total formula weight | 32275.0 |
