4KCV

Pyruvate kinase (PYK) from Trypanosoma brucei soaked with 2-oxoglutaric acid

Summary for 4KCV

Related4KCT 4KCU 4KCW 4HYV 4HYW
DescriptorPyruvate kinase 1, MAGNESIUM ION, POTASSIUM ION, ... (7 entities in total)
Functional Keywordspyruvate kinase, decarboxylase, transferase
Biological sourceTrypanosoma brucei brucei
Total number of polymer chains2
Total molecular weight110454.63
Authors
Zhong, W.,Morgan, H.P.,McNae, I.W.,Michels, P.A.M.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D. (deposition date: 2013-04-24, release date: 2014-01-08, Last modification date: 2014-02-26)
Primary citation
Zhong, W.,Morgan, H.P.,Nowicki, M.W.,McNae, I.W.,Yuan, M.,Bella, J.,Michels, P.A.,Fothergill-Gilmore, L.A.,Walkinshaw, M.D.
Pyruvate kinases have an intrinsic and conserved decarboxylase activity.
Biochem.J., 458:301-311, 2014
PubMed: 24328825 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20130790
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.18 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.19330.2%2.1%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4kcv
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Molmil generated image of 4kcv
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Molmil generated image of 4kcv
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More Biological unit images

Molmil generated image of 4kcv
no rotation
Molmil generated image of 4kcv
rotated about x axis by 90°
Molmil generated image of 4kcv
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4kcv.pdb1.gz [646.79 KB])