PDB: 3116 件ウェブページステータス検索Chemie searchBIRD

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8Q5I	Structure of Candida albicans 80S ribosome in complex with cephaeline 分子名称: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. 登録日 2023-08-09 公開日 2023-09-13 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
8RXX	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN 分子名称: 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... 著者 Rajan, K.S, Yonath, A. 登録日 2024-02-08 公開日 2024-05-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8RXH	CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN 分子名称: (2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acid, 40S ribosomal protein S12, 40S ribosomal protein S14, ... 著者 Rajan, K.S, Yonath, A. 登録日 2024-02-07 公開日 2024-05-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
8SYL	Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs 分子名称: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... 著者 Seely, S.M, Gagnon, M.G. 登録日 2023-05-25 公開日 2023-08-09 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
8EKC	Escherichia coli 70S ribosome bound to thermorubin, deacylated P-site tRNAfMet and aminoacylated A-site Phe-tRNA 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rybak, M.Y, Gagnon, M.G. 登録日 2022-09-20 公開日 2022-12-07 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin. Nucleic Acids Res., 51, 2023
4TUA	Crystal structure of ASL-Thr bound to Codon ACC-A on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-06-24 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna, 20, 2014
4TUC	Crystal structure of ASL-SufJ bound to Codon ACC-A on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-06-24 公開日 2015-05-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna, 20, 2014
4TUD	Crystal structure of ASL-SufJ bound to Codon ACC-C on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-06-24 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna, 20, 2014
4OMH	Crystal structure of the bacterial diterpene cyclase COTB2 variant F149L 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Geranylgeranyl diphosphate cyclase, SODIUM ION 著者 Janke, R, Goerner, C, Hirte, M, Brueck, T, Loll, B. 登録日 2014-01-27 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 The first structure of a bacterial diterpene cyclase: CotB2. Acta Crystallogr.,Sect.D, 70, 2014
4OMG	Crystal structure of the bacterial diterpene cyclase COTB2 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Geranylgeranyl diphosphate cyclase, SODIUM ION 著者 Janke, R, Goerner, C, Hirte, M, Brueck, T, Loll, B. 登録日 2014-01-27 公開日 2014-06-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 The first structure of a bacterial diterpene cyclase: CotB2. Acta Crystallogr.,Sect.D, 70, 2014
4TUB	Crystal structure of tRNA-Thr bound to Codon ACC-C on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-06-24 公開日 2015-05-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural insights into translational recoding by frameshift suppressor tRNASufJ. Rna, 20, 2014
4U20	Crystal structure of the E. coli ribosome bound to flopristin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. 登録日 2014-07-16 公開日 2014-07-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
4U27	Crystal structure of the E. coli ribosome bound to flopristin and linopristin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. 登録日 2014-07-16 公開日 2014-07-30 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
4U56	Crystal structure of Blasticidin S bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
8HTZ	E. coli 70S ribosome complexed with H. marismortui tRNA_Ile2 bearing agm2C34 in classical state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. 登録日 2022-12-22 公開日 2024-04-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
8HU1	E. coli 70S ribosome complexed with tRNA_Ile2 bearing L34 and ct6A37 in classical state 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Akiyama, N, Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. 登録日 2022-12-22 公開日 2024-04-03 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.69 Å) 主引用文献 Structural insights into the decoding capability of isoleucine tRNAs with lysidine and agmatidine. Nat.Struct.Mol.Biol., 31, 2024
5TGA	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... 著者 Melnikov, S, Mailliot, J. 登録日 2016-09-27 公開日 2016-11-23 最終更新日 2016-12-14 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5TGM	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... 著者 Melnikov, S, Mailliot, J, Yusupov, M. 登録日 2016-09-28 公開日 2017-01-18 最終更新日 2022-12-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
5TBW	Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D. 登録日 2016-09-13 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat Chem, 9, 2017
7K00	Structure of the Bacterial Ribosome at 2 Angstrom Resolution 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Watson, Z.L, Ward, F.R, Meheust, R, Ad, O, Schepartz, A, Banfield, J.F, Cate, J.H.D. 登録日 2020-09-02 公開日 2020-09-23 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (1.98 Å) 主引用文献 Structure of the bacterial ribosome at 2 angstrom resolution. Elife, 9, 2020
7JQM	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-002, mRNA, and deacylated P-site tRNA at 3.05A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. 登録日 2020-08-11 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
7JQL	Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. 登録日 2020-08-11 公開日 2020-08-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
5U9F	3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure II) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Demo, G, Svidritskiy, E, Madireddy, R, Diaz-Avalos, R, Grant, T, Grigorieff, N, Sousa, D, Korostelev, A.A. 登録日 2016-12-16 公開日 2017-03-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Mechanism of ribosome rescue by ArfA and RF2. Elife, 6, 2017
8IP8	Wheat 80S ribosome stalled on AUG-Stop boron dependently 分子名称: 18S ribosomal RNA, 40S ribosomal protein eL8, 40S ribosomal protein eS1, ... 著者 Yokoyama, T, Tanaka, M, Saito, H, Nishimoto, M, Tsuda, K, Sotta, N, Shigematsu, H, Shirouzu, M, Iwasaki, S, Ito, T, Fujiwara, T. 登録日 2023-03-14 公開日 2024-02-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Boric acid intercepts 80S ribosome migration from AUG-stop by stabilizing eRF1. Nat.Chem.Biol., 20, 2024
8IFC	Arbekacin-bound E.coli 70S ribosome in the PURE system 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T. 登録日 2023-02-17 公開日 2024-02-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside. J.Biochem., 175, 2024

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