4WR2
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![BU of 4wr2 by Molmil](/molmil-images/mine/4wr2) | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, Pyrimidine-specific ribonucleoside hydrolase RihA | 著者 | Himmel, D.M, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Seidel, R.D, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2014-10-22 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site To be published
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1H41
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![BU of 1h41 by Molmil](/molmil-images/mine/1h41) | Pseudomonas cellulosa E292A alpha-D-glucuronidase mutant complexed with aldotriuronic acid | 分子名称: | 1,2-ETHANEDIOL, 4-O-methyl-alpha-D-glucopyranuronic acid, ALPHA-GLUCURONIDASE, ... | 著者 | Nurizzo, D, Nagy, T, Gilbert, H.J, Davies, G.J. | 登録日 | 2002-09-25 | 公開日 | 2003-05-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The Alpha-Glucuronidase,Glca67A,of Cellvibrio Japonicus Utilizes the Carboxylate and Methyl Groups of Aldobiouronic Acid as Important Substrate Recognition Determinants J.Biol.Chem., 278, 2003
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1RAK
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![BU of 1rak by Molmil](/molmil-images/mine/1rak) | Bacterial cytosine deaminase D314S mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine. | 分子名称: | (4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE, Cytosine deaminase, FE (III) ION, ... | 著者 | Mahan, S.D, Ireton, G.C, Stoddard, B.L, Black, M.E. | 登録日 | 2003-10-31 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng.Des.Sel., 17, 2004
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4X0V
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![BU of 4x0v by Molmil](/molmil-images/mine/4x0v) | Structure of a GH5 family lichenase from Caldicellulosiruptor sp. F32 | 分子名称: | Beta-1,3-1,4-glucanase | 著者 | Meng, D, Liu, X, Wang, X, Li, F, Feng, Y. | 登録日 | 2014-11-24 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Structural Insights into the Substrate Specificity of a Glycoside Hydrolase Family 5 Lichenase from Caldicellulosiruptor sp. F32 Biochem. J., 2017
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4WRH
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![BU of 4wrh by Molmil](/molmil-images/mine/4wrh) | AKR1C3 complexed with breakdown product of N-(tert-butyl)-2-(2-chloro-4-(((3-mercapto-5-methyl-4H-1,2,4-triazol-4-yl)amino)methyl)-6-methoxyphenoxy)acetamide | 分子名称: | 1,2-ETHANEDIOL, 2-[4-(aminomethyl)-2-chloro-6-methoxyphenoxy]-N-tert-butylacetamide, 5-methyl-4H-1,2,4-triazole-3-thiol, ... | 著者 | Squire, C.J, Flanagan, J.U, Yosaatmadja, Y. | 登録日 | 2014-10-24 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Breakdown product of N-(tert-butyl)-2-(2-chloro-4-(((3-mercapto-5-methyl-4H-1,2,4-triazol-4-yl)amino)methyl)-6-methoxyphenoxy)acetamide trapped in active site of AKR1C3 To Be Published
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1RCM
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3PAH
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![BU of 3pah by Molmil](/molmil-images/mine/3pah) | HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND ADRENALINE INHIBITOR | 分子名称: | 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol, FE (III) ION, PHENYLALANINE HYDROXYLASE | 著者 | Erlandsen, H, Flatmark, T, Stevens, R.C. | 登録日 | 1998-08-20 | 公開日 | 1999-04-27 | 最終更新日 | 2013-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution. Biochemistry, 37, 1998
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1H8V
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![BU of 1h8v by Molmil](/molmil-images/mine/1h8v) | The X-ray Crystal Structure of the Trichoderma reesei Family 12 Endoglucanase 3, Cel12A, at 1.9 A Resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-BETA-1,4-GLUCANASE | 著者 | Sandgren, M, Shaw, A, Ropp, T.H, Wu, S, Bott, R, Cameron, A.D, Stahlberg, J, Mitchinson, C, Jones, T.A. | 登録日 | 2001-02-16 | 公開日 | 2001-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The X-Ray Crystal Structure of the Trichoderma Reesei Family 12 Endoglucanase 3, Cel12A, at 1.9 A Resolution J.Mol.Biol., 308, 2001
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1H13
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![BU of 1h13 by Molmil](/molmil-images/mine/1h13) | Structure of a cold-adapted family 8 xylanase | 分子名称: | ENDO-1,4-BETA-XYLANASE | 著者 | Van Petegem, F, Collins, T, Meuwis, M.A, Feller, G, Gerday, C, Van Beeumen, J. | 登録日 | 2002-07-02 | 公開日 | 2003-03-13 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The Structure of a Cold-Adapted Family 8 Xylanase at 1.3 A Resolution: Structural Adaptations to Cold and Investigation of the Active Site J.Biol.Chem., 278, 2003
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3OVQ
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![BU of 3ovq by Molmil](/molmil-images/mine/3ovq) | Crystal Structure of hRPE and D-Ribulose-5-Phospate Complex | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, FE (II) ION, RIBULOSE-5-PHOSPHATE, ... | 著者 | Liang, W.G, Ouyang, S.Y, Shaw, N, Joachimiak, A, Zhang, R.G, Liu, Z.J. | 登録日 | 2010-09-17 | 公開日 | 2011-03-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Conversion of D-ribulose 5-phosphate to D-xylulose 5-phosphate: new insights from structural and biochemical studies on human RPE Faseb J., 25, 2011
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1REA
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3OWH
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![BU of 3owh by Molmil](/molmil-images/mine/3owh) | X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, ... | 著者 | Pegan, S.D, Sturdy, M, Mesecar, A.D. | 登録日 | 2010-09-18 | 公開日 | 2011-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors. Protein Sci., 20, 2011
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3OQP
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4YYE
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1H4H
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![BU of 1h4h by Molmil](/molmil-images/mine/1h4h) | Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre | 分子名称: | XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | 著者 | Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J. | 登録日 | 2001-05-11 | 公開日 | 2002-05-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase. Chem.Biol., 6, 1999
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4ZE2
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![BU of 4ze2 by Molmil](/molmil-images/mine/4ze2) | Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) Y140H mutant complexed with itraconazole | 分子名称: | 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sagatova, A, Keniya, M.V, Wilson, R, Monk, B.C, Tyndall, J.D.A. | 登録日 | 2015-04-20 | 公開日 | 2016-03-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14 alpha-demethylase. Sci Rep, 6, 2016
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7FFR
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1H5O
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![BU of 1h5o by Molmil](/molmil-images/mine/1h5o) | Solution structure of Crotamine, a neurotoxin from Crotalus durissus terrificus | 分子名称: | MYOTOXIN | 著者 | Nicastro, G, Franzoni, L, De Chiara, C, Mancin, C.A, Giglio, J.R, Spisni, A. | 登録日 | 2001-05-23 | 公開日 | 2003-05-09 | 最終更新日 | 2013-07-24 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of Crotamine, a Na+ Channel Affecting Toxin from Crotalus Durissus Terrificus Venom Eur.J.Biochem., 270, 2003
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4ZFC
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![BU of 4zfc by Molmil](/molmil-images/mine/4zfc) | Crystal structure of AKR1C3 complexed with glicazide | 分子名称: | Aldo-keto reductase family 1 member C3, N-[(3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl]-4-methylbenzenesulfonamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhao, Y, Zhrng, X, Hu, X. | 登録日 | 2015-04-21 | 公開日 | 2015-11-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
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1R34
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![BU of 1r34 by Molmil](/molmil-images/mine/1r34) | Golgi alpha-mannosidase II complex with 5-thio-D-mannopyranosylamidinium salt | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(1Z)-2-phenylethanimidoyl]-5-thio-alpha-D-mannopyranosylamine, ... | 著者 | Kuntz, D.A, Xin, W, Kavelekar, L.M, Rose, D.R, Pinto, B.M. | 登録日 | 2003-09-30 | 公開日 | 2004-11-02 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | 5-Thio-d-glycopyranosylamines and their amidinium salts as potential transition-state mimics of glycosyl hydrolases: synthesis, enzyme inhibitory activities, X-ray crystallography, and molecular modeling TETRAHEDRON ASYMMETRY, 16, 2005
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1R43
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![BU of 1r43 by Molmil](/molmil-images/mine/1r43) | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein) | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ... | 著者 | Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D. | 登録日 | 2003-10-03 | 公開日 | 2003-11-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases J.Biol.Chem., 278
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7FFS
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3OZ2
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1RRM
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4Z24
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![BU of 4z24 by Molmil](/molmil-images/mine/4z24) | |