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1QQ6
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BU of 1qq6 by Molmil
STRUCTURE OF L-2-HALOACID DEHALOGENASE FROM XANTHOBACTER AUTOTROPHICUS WITH CHLOROACETIC ACID COVALENTLY BOUND
分子名称: CHLORIDE ION, PROTEIN (L-2-HALOACID DEHALOGENASE)
著者Ridder, I.S, Rozeboom, H.J, Kalk, K.H, Dijkstra, B.W.
登録日1999-06-11
公開日1999-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of intermediates in the dehalogenation of haloalkanoates by L-2-haloacid dehalogenase.
J.Biol.Chem., 274, 1999
3TNP
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BU of 3tnp by Molmil
Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
6QVH
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BU of 6qvh by Molmil
Streptomyces lividans Ccsp mutant - H113A
分子名称: COPPER (I) ION, cytosolic copper storage protein
著者Straw, M.L, Hough, M.A.
登録日2019-03-01
公開日2019-07-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献A Histidine Residue and a Tetranuclear Cuprous-thiolate Cluster Dominate the Copper Loading Landscape of a Copper Storage Protein from Streptomyces lividans.
Chemistry, 25, 2019
3TQZ
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BU of 3tqz by Molmil
Structure of a deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) from Coxiella burnetii
分子名称: Deoxyuridine 5'-triphosphate nucleotidohydrolase, SULFATE ION
著者Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
登録日2011-09-09
公開日2011-09-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
4HPU
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BU of 4hpu by Molmil
Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying partial phosphoryl transfer of AMP-PNP onto a substrate peptide
分子名称: MAGNESIUM ION, MYRISTIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Bastidas, A.C, Steichen, J.M, Wu, J, Taylor, S.S.
登録日2012-10-24
公開日2013-03-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Phosphoryl transfer by protein kinase a is captured in a crystal lattice.
J.Am.Chem.Soc., 135, 2013
3KFI
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Major mouse urinary protein IV complexed with 2,5-dimethylpyrazine
分子名称: 2,5-dimethylpyrazine, CHLORIDE ION, Major urinary protein 4
著者Perez-Miller, S, Zou, Q, Hurley, T.D.
登録日2009-10-27
公開日2010-06-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Protein Sci., 19, 2010
6IAJ
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BU of 6iaj by Molmil
Sixty minutes iron loaded Rana Catesbeiana H' ferritin variant H54N
分子名称: CHLORIDE ION, FE (II) ION, Ferritin, ...
著者Pozzi, C, Di Pisa, F, Mangani, S.
登録日2018-11-26
公開日2019-05-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H' ferritin.
J.Inorg.Biochem., 197, 2019
4HS1
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BU of 4hs1 by Molmil
High-resolution crystal structure of Glutaredoxin like protein NrdH from Mycobacterium tuberculosis.
分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Phulera, S, Mande, S.C.
登録日2012-10-29
公開日2013-06-26
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (0.87 Å)
主引用文献The Crystal Structure of Mycobacterium tuberculosis NrdH at 0.87 A Suggests a Possible Mode of Its Activity.
Biochemistry, 52, 2013
8DKE
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Cryo-EM structure of cystinosin in a cytosol-open state
分子名称: Fab 3H5 Heavy chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin
著者Schmiege, P, Li, X.
登録日2022-07-05
公開日2022-09-21
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
3O8Y
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BU of 3o8y by Molmil
Stable-5-Lipoxygenase
分子名称: Arachidonate 5-lipoxygenase, FE (II) ION
著者Newcomer, M.E, Gilbert, N.C, Bartlett, S.G, Waight, M.T, Neau, D.B, Boeglin, W.E, Brash, A.R.
登録日2010-08-03
公開日2011-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.389 Å)
主引用文献The structure of human 5-lipoxygenase.
Science, 331, 2011
2Z5U
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BU of 2z5u by Molmil
Crystal structure of Lysine-specific histone demethylase 1
分子名称: FAD-trans-2-Phenylcyclopropylamine Adduct, Lysine-specific histone demethylase 1
著者Mimasu, S, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-07-17
公開日2008-04-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A
Biochem.Biophys.Res.Commun., 366, 2008
8DKW
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Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH5.0
分子名称: Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin
著者Schmiege, P, Li, X.
登録日2022-07-06
公開日2022-09-21
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
3WLX
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Crystal structure of low-specificity L-threonine aldolase from Escherichia coli
分子名称: Low specificity L-threonine aldolase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]
著者Qin, H.-M, Imai, F.L, Miyakawa, T, Kataoka, M, Okai, M, Hou, F, Ohtsuka, J, Nagata, K, Shimizu, S, Tanokura, M.
登録日2013-11-15
公開日2014-12-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure analysis of L-threonine aldolase from Escherichia coli unravels the low-specificity and thermostability
To be Published
3KFF
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BU of 3kff by Molmil
Major mouse urinary protein IV complexed with 2-sec-butyl-4,5-dihydrothiazole
分子名称: 2-[(1R)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, 2-[(1S)-1-methylpropyl]-4,5-dihydro-1,3-thiazole, CHLORIDE ION, ...
著者Perez-Miller, S, Zou, Q, Hurley, T.D.
登録日2009-10-27
公開日2010-06-16
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Protein Sci., 19, 2010
8DKI
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BU of 8dki by Molmil
Cryo-EM structure of cystinosin in a lumen-open state
分子名称: Fab 3H5 Heavy Chain, Fab 3H5 Kappa chain, Isoform 2 of Cystinosin
著者Schmiege, P, Li, X.
登録日2022-07-05
公開日2022-09-21
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
6U4T
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Carbonic anhydrase 9 in complex with SB4197
分子名称: 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION
著者Murray, A.B, Lomelino, C.L, McKenna, R.
登録日2019-08-26
公開日2020-01-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.356 Å)
主引用文献"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020
8DYO
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BU of 8dyo by Molmil
Cryo-EM structure of Importin-4 bound to RanGTP
分子名称: GTP-binding nuclear protein GSP1/CNR1, GUANOSINE-5'-TRIPHOSPHATE, Importin-4, ...
著者Bernardes, N.E, Fung, H.Y.J, Li, Y, Chen, Z, Chook, Y.M.
登録日2022-08-04
公開日2022-09-21
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (7.1 Å)
主引用文献Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex.
Proc.Natl.Acad.Sci.USA, 119, 2022
6UFD
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BU of 6ufd by Molmil
Carbonic anhydrase 2 with inhibitor (2Z)-3-oxo-N-(4-sulfamoylphenyl)-2-[(thiophen-2-yl)methylidene]butanamide (11g/D7)
分子名称: (2Z)-3-oxo-N-(4-sulfamoylphenyl)-2-[(thiophen-2-yl)methylidene]butanamide, CHLORIDE ION, Carbonic anhydrase 2, ...
著者Peat, T.S.
登録日2019-09-24
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action.
J.Med.Chem., 63, 2020
2ZD7
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The structure of VPS75 (Vacuolar protein sorting-associated protein 75)
分子名称: EVDLPLSDEEPSS, Vacuolar protein sorting-associated protein 75
著者Park, Y.J, Luger, K.
登録日2007-11-20
公開日2008-08-12
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Histone chaperone specificity in Rtt109 activation.
Nat.Struct.Mol.Biol., 15, 2008
3TUE
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BU of 3tue by Molmil
The structure of tryparedoxin peroxidase I from Leishmania major
分子名称: Tryparedoxin peroxidase
著者Fiorillo, A, Ilari, A, Colotti, G.
登録日2011-09-16
公開日2012-09-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The crystal structures of the tryparedoxin-tryparedoxin peroxidase couple unveil the structural determinants of leishmania detoxification pathway.
Plos Negl Trop Dis, 6, 2012
3HHQ
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BU of 3hhq by Molmil
Crystal structure of apo dUT1p from Saccharomyces cerevisiae
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Singer, A.U, Evdokimova, E, Kudritska, M, Dong, A, Edwards, A.M, Yakunin, A.F, Savchenko, A.
登録日2009-05-15
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and activity of the Saccharomyces cerevisiae dUTP pyrophosphatase DUT1, an essential housekeeping enzyme.
Biochem.J., 437, 2011
6UGQ
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Human Carbonic Anhydrase IX-mimic complexed with SB4-206
分子名称: 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION
著者Murray, A.B, Lomelino, C.L, McKenna, R.
登録日2019-09-26
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.305 Å)
主引用文献"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020
1QUW
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BU of 1quw by Molmil
SOLUTION STRUCTURE OF THE THIOREDOXIN FROM BACILLUS ACIDOCALDARIUS
分子名称: THIOREDOXIN
著者Nicastro, G, de Chiara, C, Pedone, E, Tato, M, Rossi, M.
登録日1999-07-02
公開日2000-01-26
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献NMR solution structure of a novel thioredoxin from Bacillus acidocaldarius possible determinants of protein stability.
Eur.J.Biochem., 267, 2000
8DKX
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Cryo-EM structure of cystinosin N288K mutant in a cytosol-open state at pH7.5
分子名称: Fab 3H5 Heavy Chain, Fab 3H5 Kappa Chain, Isoform 2 of Cystinosin
著者Schmiege, P, Li, X.
登録日2022-07-06
公開日2022-09-21
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and mechanism of human cystine exporter cystinosin.
Cell, 185, 2022
6UOL
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Y271G DNA polymerase beta substrate complex with a templating cytosine and incoming rGTP
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Smith, M.R, Freudenthal, B.D.
登録日2019-10-15
公開日2020-01-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.936 Å)
主引用文献Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta.
J.Biol.Chem., 295, 2020

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件を2025-07-09に公開中

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