2FR1
 
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6CD1
 | | Crystal structure of Medicago truncatula serine hydroxymethyltransferase 3 (MtSHMT3), complexes with reaction intermediates | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, GLYCINE, ... | | 著者 | Ruszkowski, M, Sekula, B, Ruszkowska, A, Dauter, Z. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Chloroplastic Serine Hydroxymethyltransferase FromMedicago truncatula: A Structural Characterization.
Front Plant Sci, 9, 2018
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6CTL
 | | Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHCL-R/S isomers, beta, gamma dTTP analogue | | 分子名称: | 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]thymidine, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | | 著者 | Batra, V.K, Wilson, S.H. | | 登録日 | 2018-03-23 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
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6CEH
 | | Design, Synthesis, X-ray and Biological Activities of Selenides Bearing the Benzenesulfonamide Moiety as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology | | 分子名称: | 4-[(prop-2-en-1-yl)selanyl]benzene-1-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | | 著者 | Peat, T.S, Angeli, A, di Cesare Mannelli, L, Trallori, E, Ghelardini, C, Carta, F, Supuran, C.T. | | 登録日 | 2018-02-11 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology.
ACS Med Chem Lett, 9, 2018
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1ERR
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3DLK
 | | Crystal Structure of an engineered form of the HIV-1 Reverse Transcriptase, RT69A | | 分子名称: | Reverse transcriptase/ribonuclease H, SULFATE ION, p51 RT | | 著者 | Ho, W.C, Bauman, J.D, Himmel, D.M, Das, K, Arnold, E. | | 登録日 | 2008-06-27 | | 公開日 | 2008-10-07 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.
Nucleic Acids Res., 36, 2008
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1ETX
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2FVU
 | | Structure of the yeast Sir3 BAH domain | | 分子名称: | Regulatory protein SIR3 | | 著者 | Xu, R.M. | | 登録日 | 2006-01-31 | | 公開日 | 2006-09-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and function of the Saccharomyces cerevisiae Sir3 BAH domain.
Mol.Cell.Biol., 26, 2006
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1ETK
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1ETY
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4AYB
 | | RNAP at 3.2Ang | | 分子名称: | DNA-DIRECTED RNA POLYMERASE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | | 著者 | Wojtas, M.N, Mogni, M, Millet, O, Bell, S.D, Abrescia, N.G.A. | | 登録日 | 2012-06-19 | | 公開日 | 2012-08-08 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | | 主引用文献 | Structural and Functional Analyses of the Interaction of Archaeal RNA Polymerase with DNA.
Nucleic Acids Res., 40, 2012
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6CE9
 | | Insulin Receptor ectodomain in complex with two insulin molecules | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. | | 登録日 | 2018-02-11 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
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4IDR
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3PDN
 | | Crystal structure of SmyD3 in complex with methyltransferase inhibitor sinefungin | | 分子名称: | GLYCEROL, MAGNESIUM ION, SET and MYND domain-containing protein 3, ... | | 著者 | Sirinupong, N, Brunzelle, J, Yang, Z. | | 登録日 | 2010-10-23 | | 公開日 | 2010-11-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Insights into the Autoinhibition and Posttranslational Activation of Histone Methyltransferase SmyD3.
J.Mol.Biol., 406, 2011
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1YEX
 | | Structural and biochemical analysis of the link between enzymatic activity and oligomerization in AhpC, a bacterial peroxiredoxin. | | 分子名称: | Alkyl hydroperoxide reductase subunit C, SULFATE ION | | 著者 | Parsonage, D, Youngblood, D.S, Sarma, G.N, Wood, Z.A, Karplus, P.A, Poole, L.B. | | 登録日 | 2004-12-28 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Analysis of the Link between Enzymatic Activity and Oligomeric State in AhpC, a Bacterial Peroxiredoxin.
Biochemistry, 44, 2005
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3PER
 | | Crystal Structure of BoxB with phosphate bound to the diiron center | | 分子名称: | Benzoyl-CoA oxygenase component B, FE (III) ION, GLYCEROL, ... | | 著者 | Weinert, T, Rather, L.J, Fuchs, G, Ermler, U. | | 登録日 | 2010-10-27 | | 公開日 | 2011-06-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and Mechanism of the Diiron Benzoyl-Coenzyme A Epoxidase BoxB.
J.Biol.Chem., 286, 2011
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6CR7
 | | Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CHF, beta, gamma dATP analogue | | 分子名称: | 9-{2-deoxy-5-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-alpha-D-erythro-pentofuranosyl}-9H-purin-6-amine, CHLORIDE ION, DNA polymerase beta, ... | | 著者 | Batra, V.K, Wilson, S.H. | | 登録日 | 2018-03-16 | | 公開日 | 2018-07-04 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs.
Biochemistry, 57, 2018
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6CNN
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3N2P
 | | Crystal structure of human carbonic anhydrase II in complex with a benzenesulfonamide inhibitor | | 分子名称: | 4-{[(3-nitrophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Avvaru, B.S, Wagner, J, Robbins, A.H, McKenna, R. | | 登録日 | 2010-05-18 | | 公開日 | 2011-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | | 主引用文献 | Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
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4B63
 | | A. fumigatus ornithine hydroxylase (SidA) bound to NADP and ornithine | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ... | | 著者 | Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A. | | 登録日 | 2012-08-09 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases.
Biochemistry, 51, 2012
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3MZC
 | | Human carbonic ahydrase II in complex with a benzenesulfonamide inhibitor | | 分子名称: | 4-[(cyclopentylcarbamoyl)amino]benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | | 著者 | Avvaru, B.S, Wagner, J, Robbins, A.H, Mckenna, R. | | 登録日 | 2010-05-12 | | 公開日 | 2011-03-09 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.498 Å) | | 主引用文献 | Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency.
Chem.Commun.(Camb.), 46, 2010
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1ENK
 | | CRYSTAL STRUCTURE OF A PYRIMIDINE DIMER SPECIFIC EXCISION REPAIR ENZYME FROM BACTERIOPHAGE T4: REFINEMENT AT 1.45 ANGSTROMS AND X-RAY ANALYSIS OF THE THREE ACTIVE SITE MUTANTS | | 分子名称: | ENDONUCLEASE V | | 著者 | Vassylyev, D.G, Ariyoshi, M, Matsumoto, O, Katayanagi, K, Ohtsuka, E, Morikawa, K. | | 登録日 | 1994-08-08 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants.
J.Mol.Biol., 249, 1995
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3GHT
 | | Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Third stage of radiation damage. | | 分子名称: | Aldose reductase, CITRIC ACID, IDD594, ... | | 著者 | Petrova, T, Ginell, S, Hazemann, I, Mitschler, A, Podjarny, A, Joachimiak, A. | | 登録日 | 2009-03-04 | | 公開日 | 2009-03-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | X-ray-radiation-induced cooperative atomic movements in protein.
J.Mol.Biol., 387, 2009
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3GHQ
 | | Crystal Structure of E. coli W35F BFR mutant | | 分子名称: | Bacterioferritin, FE (III) ION, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Crow, A, Lawson, T.L, Lewin, A, Moore, G.R, Le Brun, N.E. | | 登録日 | 2009-03-04 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Monitoring the iron status of the ferroxidase center of Escherichia coli bacterioferritin using fluorescence spectroscopy.
Biochemistry, 48, 2009
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2ARF
 | | Solution structure of the Wilson ATPase N-domain in the presence of ATP | | 分子名称: | WILSON DISEASE ATPASE | | 著者 | Dmitriev, O, Tsivkovskii, R, Abildgaard, F, Morgan, C.T, Markley, J.L, Lutsenko, S. | | 登録日 | 2005-08-19 | | 公開日 | 2006-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the N-domain of Wilson disease protein: Distinct nucleotide-binding environment and effects of disease mutations
Proc.Natl.Acad.Sci.Usa, 103, 2006
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