7FYD

Crystal Structure of human FABP5 in complex with 6-chloro-4-phenyl-2-propan-2-ylquinoline-3-carboxylic acid, i.e. SMILES c1(ccc2c(c1)c(c1ccccc1)c(c(n2)C(C)C)C(=O)O)Cl with IC50=2.6 microM

Summary for 7FYD

• Entry DOI: 10.2210/pdb7fyd/pdb
• Group deposition: To be published (G_1002264)
• Descriptor: Fatty acid-binding protein 5, DIMETHYL SULFOXIDE, SULFATE ION, ... (5 entities in total)
• Functional Keywords: lipid binding protein, fatty acid binding protein, cytoplasm, lipid-binding, transport, protein binding
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 16063.78

Authors

Ehler, A.,Benz, J.,Obst, U.,Ceccarelli-Simona, M.,Rudolph, M.G. (deposition date: 2023-04-27, release date: 2023-06-14, Last modification date: 2024-11-20)

• Primary citation: Obst, U.,Magnone, C.,Kuhn, B.,Rudolph, M.G.; Crystal Structure of a human FABP5 complex; To be published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)