5NDX
 
 | | The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent: Crystallography and QM/MM insights into Mucopolysaccharidosis I | | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{S})-6-(4-methyl-2-oxidanylidene-chromen-7-yl)oxy-3,4,5-tris(oxidanyl)oxane-2-carboxylic acid, Glycosyl hydrolase, SULFATE ION | | 著者 | Raich, L, Valero-Gonzalez, J, Castro-Lopez, J, Millan, C, Jimenez-Garcia, M.J, Nieto, P, Uson, I, Hurtado-Guerrero, R, Rovira, C. | | 登録日 | 2017-03-09 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The bacterial orthologue of Human a-L-iduronidase does not need N-glycan post-translational modifications to be catalytically competent:
Crystallography and QM/MM insights into Mucopolysaccharidosis I.
To Be Published
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5MVL
 | | Crystal structure of an A-DNA dodecamer containing 5-bromouracil | | 分子名称: | Brominated DNA dodecamer, MAGNESIUM ION | | 著者 | Hardwick, J.S, Ptchelkine, D, Phillips, S.E.V, Brown, T. | | 登録日 | 2017-01-16 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.405 Å) | | 主引用文献 | 5-Formylcytosine does not change the global structure of DNA.
Nat. Struct. Mol. Biol., 24, 2017
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4TNN
 | | Crystal structure of Escherichia coli protein YodA in complex with Ni - artifact of purification. | | 分子名称: | Metal-binding lipocalin, NICKEL (II) ION, SULFATE ION | | 著者 | Gasiorowska, O.A, Cymborowski, M.T, Handing, K.B, Shabalin, I.G, Zasadzinska, E, Niedzialkowska, E, Porebski, P.J, Minor, W. | | 登録日 | 2014-06-04 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Protein purification and crystallization artifacts: The tale usually not told.
Protein Sci., 25, 2016
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4U6R
 | | Crystal structure of human IRE1 cytoplasmic domains in complex with a sulfonamide inhibitor. | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]-3-methylnaphthalen-1-yl}-2-chlorobenzenesulfonamide, ... | | 著者 | Mohr, C. | | 登録日 | 2014-07-29 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Unfolded Protein Response in Cancer: IRE1 alpha Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.
Acs Med.Chem.Lett., 6, 2015
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7O0N
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8BTW
 | | Structure of D179N BlaC from Mycobacterium tuberculosis in complex with vaborbactam | | 分子名称: | Beta-lactamase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Chikunova, A, Bruenle, S, Ubbink, M. | | 登録日 | 2022-12-02 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Asp179 in the class A beta-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis.
Febs J., 290, 2023
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8BTV
 | | Structure of D179N BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct of sulbactam | | 分子名称: | Beta-lactamase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Chikunova, A, Bruenle, S, Ubbink, M. | | 登録日 | 2022-12-02 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Asp179 in the class A beta-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis.
Febs J., 290, 2023
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8BTU
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8BV4
 | | Structure of BlaC from Mycobacterium tuberculosis in complex with vaborbactam | | 分子名称: | Beta-lactamase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Chikunova, A, Bruenle, S, Ubbink, M. | | 登録日 | 2022-12-01 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Asp179 in the class A beta-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis.
Febs J., 290, 2023
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4KY9
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1ZYT
 | | Crystal structure of spin labeled T4 Lysozyme (A82R1) | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | | 登録日 | 2005-06-10 | | 公開日 | 2006-08-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | EPR (1.7 Å), X-RAY DIFFRACTION | | 主引用文献 | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins
Protein Sci., 18, 2009
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7F3U
 | | Cryo-EM structure of human TMEM120A in the CoASH-free state | | 分子名称: | Transmembrane protein 120A | | 著者 | Rong, Y, Gao, Y.W, Song, D.F, Zhao, Y, Liu, Z.F. | | 登録日 | 2021-06-17 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells.
Elife, 10, 2021
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7F3T
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6YYI
 | | Crystal structure of beta-D-xylosidase from Dictyoglomus thermophilum bound to beta-D-xylopyranose | | 分子名称: | 1,2-ETHANEDIOL, Beta-xylosidase, CITRIC ACID, ... | | 著者 | Lafite, P, Daniellou, R, Bretagne, D. | | 登録日 | 2020-05-05 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal structure of Dictyoglomus thermophilum beta-d-xylosidase DtXyl unravels the structural determinants for efficient notoginsenoside R1 hydrolysis.
Biochimie, 181, 2020
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6YYH
 | | Crystal structure of beta-D-xylosidase from Dictyoglomus thermophilum in ligand-free form | | 分子名称: | 1,2-ETHANEDIOL, Beta-xylosidase, CITRIC ACID, ... | | 著者 | Lafite, P, Daniellou, R, Bretagne, D. | | 登録日 | 2020-05-05 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Crystal structure of Dictyoglomus thermophilum beta-d-xylosidase DtXyl unravels the structural determinants for efficient notoginsenoside R1 hydrolysis.
Biochimie, 181, 2020
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4DNB
 | | METHYLATION OF THE ECORI RECOGNITION SITE DOES NOT ALTER DNA CONFORMATION. THE CRYSTAL STRUCTURE OF D(CGCGAM6ATTCGCG) AT 2.0 ANGSTROMS RESOLUTION | | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*(6MA)P*TP*TP*CP*GP*CP*G)-3') | | 著者 | Frederick, C.A, Quigley, G.J, Van Der Marel, G.A, Van Boom, J.H, Wang, A.H.-J, Rich, A. | | 登録日 | 1988-08-29 | | 公開日 | 1989-01-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Methylation of the EcoRI recognition site does not alter DNA conformation: the crystal structure of d(CGCGAm6ATTCGCG) at 2.0-A resolution.
J.Biol.Chem., 263, 1988
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6YM9
 | | Mycobacterium tuberculosis FtsZ in complex with GTP-gamma-S | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein FtsZ | | 著者 | Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F. | | 登録日 | 2020-04-08 | | 公開日 | 2021-04-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
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6Y1V
 | | Mycobacterium tuberculosis FtsZ-GTP-gamma-S in complex with 4-hydroxycoumarin | | 分子名称: | 4-HYDROXY-2H-CHROMEN-2-ONE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Cell division protein FtsZ, ... | | 著者 | Alnami, A.T, Norton, R.S, Pena, H.P, Haider, M, kozielski, F. | | 登録日 | 2020-02-13 | | 公開日 | 2021-06-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Conformational Flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ.
J.Mol.Biol., 433, 2021
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5MVX
 | | Human DLL4 C2-EGF3 | | 分子名称: | Delta-like protein 4, alpha-L-fucopyranose | | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | | 登録日 | 2017-01-17 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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6O9I
 | | Ternary complex of mouse ECD with Fab1 and Fab2 | | 分子名称: | 1,2-ETHANEDIOL, Fab 2 heavy chain, Fab1 heavy chain, ... | | 著者 | Min, X, Wang, Z. | | 登録日 | 2019-03-13 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.
Mabs, 12, 2020
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6O9H
 | | Mouse ECD with Fab1 | | 分子名称: | Gastric inhibitory polypeptide receptor, Heavy chain, Light chain, ... | | 著者 | Min, X, Wang, Z. | | 登録日 | 2019-03-13 | | 公開日 | 2020-01-22 | | 最終更新日 | 2020-04-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.
Mabs, 12, 2020
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5KY2
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7RTX
 | | Actophorin grown in microgravity | | 分子名称: | Actophorin | | 著者 | Lieberman, R.L, Quirk, S. | | 登録日 | 2021-08-16 | | 公開日 | 2021-12-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Improved resolution crystal structure of Acanthamoeba actophorin reveals structural plasticity not induced by microgravity.
Acta Crystallogr.,Sect.F, 77, 2021
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5U01
 | | Cooperative DNA binding by two RelA dimers | | 分子名称: | DNA (27-MER), Transcription factor p65 | | 著者 | Ghosh, G, Huang, D. | | 登録日 | 2016-11-22 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor kappa B are not correlated.
J. Biol. Chem., 292, 2017
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5KXQ
 | | mouse POFUT1 in complex with GDP | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP-fucose protein O-fucosyltransferase 1, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Li, Z, Rini, J.M. | | 登録日 | 2016-07-20 | | 公開日 | 2017-05-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
Nat. Chem. Biol., 13, 2017
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