8BTW
Structure of D179N BlaC from Mycobacterium tuberculosis in complex with vaborbactam
Summary for 8BTW
| Entry DOI | 10.2210/pdb8btw/pdb |
| Descriptor | Beta-lactamase, Vaborbactam, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Total number of polymer chains | 1 |
| Total formula weight | 29207.23 |
| Authors | Chikunova, A.,Bruenle, S.,Ubbink, M. (deposition date: 2022-12-02, release date: 2023-07-05, Last modification date: 2023-11-22) |
| Primary citation | van Alen, I.,Chikunova, A.,van Zanten, D.B.,de Block, A.A.,Timmer, M.,Brunle, S.,Ubbink, M. Asp179 in the class A beta-lactamase from Mycobacterium tuberculosis is a conserved yet not essential residue due to epistasis. Febs J., 290:4933-4949, 2023 Cited by PubMed: 37335937DOI: 10.1111/febs.16892 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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