8BTW
Structure of D179N BlaC from Mycobacterium tuberculosis in complex with vaborbactam
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 266 | 28328.8 | 1 | UniProt (P9WKD2) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Ambler class A beta-lactamase |
| 2 | B (A) | Vaborbactam | non-polymer | 297.1 | 1 | Chemie (4D6) | |||
| 3 | C, D, E, F (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | G, H (A) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | I (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | J (A) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A: 28 - 293 (UniProt: P9WKD2)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Asn 179 | Asp 195 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28328.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 878.4 | |
| All* | Total formula weight | 29207.2 |
