5KIW
| p97 ND1-L198W in complex with VIMP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | 著者 | Tang, W.K, Xia, D. | 登録日 | 2016-06-17 | 公開日 | 2018-03-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane. Cell Discov, 3, 2017
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8B5R
| p97-p37-SPI substrate complex | 分子名称: | I3 sequence being threaded through the p97 channel, Protein phosphatase 1 regulatory subunit 7, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit, ... | 著者 | van den Boom, J, Marini, G, Meyer, H, Saibil, H. | 登録日 | 2022-09-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural basis of ubiquitin-independent PP1 complex disassembly by p97. Embo J., 42, 2023
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8B98
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8B96
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5I88
| BRD4 in complex with Cpd4 ((E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide) | 分子名称: | 1,2-ETHANEDIOL, 3-{6-[(2E)-but-2-en-1-yl]-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl}-N,N-dimethylbenzamide, Bromodomain-containing protein 4, ... | 著者 | Murray, J.M. | 登録日 | 2016-02-18 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains. J.Med.Chem., 59, 2016
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5IAY
| NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Spacer | 著者 | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | 登録日 | 2016-02-22 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
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8BOX
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8BOP
| LSD1-CoREST in complex with AW4, long soaking | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S})-5-[7,8-dimethyl-2,4-bis(oxidanylidene)-5-[3-[4-(3-phenylphenyl)phenyl]propanoyl]-1~{H}-benzo[g]pteridin-10-yl]-2,3,4-tris(oxidanyl)pentyl] hydrogen phosphate | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2022-11-15 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
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8C9J
| Crystal structure of human NQO1 by serial femtosecond crystallography | 分子名称: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1 | 著者 | Martin-Garcia, J.M, Grieco, A, Ruiz-Fresneda, M.A, Pacheco-Garcia, J.L, Pey, A, Botha, S, Ros, A. | 登録日 | 2023-01-23 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Modular droplet injector for sample conservation providing new structural insight for the conformational heterogeneity in the disease-associated NQO1 enzyme. Lab Chip, 23, 2023
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3HU1
| Structure of p97 N-D1 R95G mutant in complex with ATPgS | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Tang, W.-K. | 登録日 | 2009-06-12 | 公開日 | 2010-06-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants. Embo J., 29, 2010
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3HQH
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3LRE
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5K4L
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3L6Y
| Crystal structure of p120 catenin in complex with E-cadherin | 分子名称: | Catenin delta-1, E-cadherin | 著者 | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | 登録日 | 2009-12-27 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.), 141, 2010
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5KO9
| Crystal Structure of the SRAP Domain of Human HMCES Protein | 分子名称: | Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein, UNKNOWN ATOM OR ION | 著者 | Halabelian, L, Li, Y, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2016-06-29 | 公開日 | 2016-08-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
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8COB
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3L6X
| Crystal structure of p120 catenin in complex with E-cadherin | 分子名称: | Catenin delta-1, E-cadherin, SULFATE ION | 著者 | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | 登録日 | 2009-12-27 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell(Cambridge,Mass.), 141, 2010
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5L6W
| Structure Of the LIMK1-ATPgammaS-CFL1 Complex | 分子名称: | Cofilin-1, LIM domain kinase 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | 著者 | Salah, E, Mathea, S, Oerum, S, Newman, J.A, Tallant, C, Adamson, R, Canning, P, Beltrami, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Bullock, A.N. | 登録日 | 2016-05-31 | 公開日 | 2016-06-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Structure Of the LIMK1-ATPgammaS-CFL1 Complex To Be Published
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5L3D
| Human LSD1/CoREST: LSD1 Y761H mutation | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1 | 著者 | Pilotto, S, Speranzini, V, Marabelli, C, Mattevi, A. | 登録日 | 2016-04-06 | 公開日 | 2016-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors. Hum.Mol.Genet., 25, 2016
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5KIY
| p97 ND1-A232E in complex with VIMP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ... | 著者 | Tang, W.K, Xia, D. | 登録日 | 2016-06-17 | 公開日 | 2017-12-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structural basis for nucleotide-modulated p97 association with the ER membrane. Cell Discov, 3, 2017
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3HU3
| Structure of p97 N-D1 R155H mutant in complex with ATPgS | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase | 著者 | Tang, W.-K. | 登録日 | 2009-06-12 | 公開日 | 2010-06-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants. Embo J., 29, 2010
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5KV0
| Human cyclophilin A at 278K, Data set 2 | 分子名称: | Peptidyl-prolyl cis-trans isomerase A | 著者 | Russi, S, Gonzalez, A, Kenner, L.R, Keedy, D.A, Fraser, J.S, van den Bedem, H. | 登録日 | 2016-07-13 | 公開日 | 2016-08-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Conformational variation of proteins at room temperature is not dominated by radiation damage. J Synchrotron Radiat, 24, 2017
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5KY6
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5L3B
| Human LSD1/CoREST: LSD1 D556G mutation | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, REST corepressor 1 | 著者 | Pilotto, S, Speranzini, V, Marabelli, C. | 登録日 | 2016-04-06 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | LSD1/KDM1A mutations associated to a newly described form of intellectual disability impair demethylase activity and binding to transcription factors. Hum.Mol.Genet., 25, 2016
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3I7P
| Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR40A | 分子名称: | DNA damage-binding protein 1, WD repeat-containing protein 40A | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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