PDB: 187313 件ウェブページステータス検索Chemie searchBIRD

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7DOR	E. coli GyrB ATPase domain in complex with 4-nitropheno 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, P-NITROPHENOL, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-16 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DPR	E. coli GyrB ATPase domain in complex with methyl 3,4-dihydroxybenzoate 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-21 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQH	E. coli GyrB ATPase domain in complex with 2-hydroxybenzamide 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-23 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQI	E. coli GyrB ATPase domain in complex with Esculetin 分子名称: 1H-benzimidazol-2-amine, 6,7-bis(oxidanyl)chromen-2-one, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-23 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQJ	E. coli GyrB ATPase domain in complex with 3,4-Dihydroxyacetophenone 分子名称: 1-[3,4-bis(oxidanyl)phenyl]ethanone, 1H-benzimidazol-2-amine, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQF	E. coli GyrB ATPase domain in complex with methyl 2,4-dihydroxybenzoate 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-23 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQU	E. coli GyrB ATPase domain in complex with methyl 4-hydroxybenzoate 分子名称: 1H-benzimidazol-2-amine, 4-HYDROXY-BENZOIC ACID METHYL ESTER, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQL	E. coli GyrB ATPase domain in complex with 4-chlorobenzene-1,2-diol 分子名称: 1H-benzimidazol-2-amine, 4-CHLOROBENZENE-1,2-DIOL, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQM	E. coli GyrB ATPase domain in complex with Naringenin 分子名称: 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQS	E. coli GyrB ATPase domain in complex with 2-chlorophenol 分子名称: 1H-benzimidazol-2-amine, 2-CHLOROPHENOL, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
7DQW	E. coli GyrB ATPase domain in complex with 4-chlorophenol 分子名称: 1H-benzimidazol-2-amine, 4-chlorophenol, DNA gyrase subunit B, ... 著者 Yu, Y, Zhou, H. 登録日 2020-12-24 公開日 2021-10-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
4DUW	E. coli (lacZ) beta-galactosidase (G974A) in complex with allolactose 分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E. 登録日 2012-02-22 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Explanation for Allolactose (lac operon inducer) Synthesis by lacZ beta-Galactosidase and the Evolutionary Relationship between Allolactose synthesis and the lac Repressor J.Biol.Chem., 288, 2013
1PX4	E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) WITH IPTG BOUND 分子名称: 1-methylethyl 1-thio-beta-D-galactopyranoside, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. 登録日 2003-07-02 公開日 2004-06-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase Biochemistry, 42, 2003
4FYW	E. coli Aspartate Transcarbamoylase complexed with CTP 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Cockrell, G.M, Kantrowitz, E.R. 登録日 2012-07-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
4FYX	E. coli Aspartate Transcarbamoylase complexed with dCTP, UTP, and Mg2+ 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ... 著者 Cockrell, G.M, Kantrowitz, E.R. 登録日 2012-07-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.0889 Å) 主引用文献 Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
3BFI	E. Coli Thymidylate Synthase Y209M mutant complexed with 5-nitro-dUMP 分子名称: 2'-DEOXY-5-NITROURIDINE 5'-MONOPHOSPHATE, SULFATE ION, Thymidylate synthase 著者 Roberts, S.A, Montfort, W.R. 登録日 2007-11-21 公開日 2008-12-02 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 E.Coli thymidylate synthase complexed with 5-NITRO-2'-DEOXY URIDINE To be Published
1SKU	E. coli Aspartate Transcarbamylase 240's Loop Mutant (K244N) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ... 著者 Alam, N, Stieglitz, K.A, Caban, M.D, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. 登録日 2004-03-05 公開日 2004-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase. J.Biol.Chem., 279, 2004
6KJ9	E. coli ATCase catalytic subunit mutant - G128/130A 分子名称: Aspartate carbamoyltransferase catalytic subunit 著者 Lei, Z, Zheng, J, Jia, Z.C. 登録日 2019-07-22 公開日 2020-03-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
4DUV	E. coli (lacZ) beta-galactosidase (G974A) 2-deoxy-galactosyl-enzyme and bis-Tris complex 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-deoxy-alpha-D-galactopyranose, Beta-galactosidase, ... 著者 Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E. 登録日 2012-02-22 公開日 2013-04-03 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Glucose Acceptor site of lacZ beta-galactosidase for the synthesis of allolactose - the natural inducer of the lac operon To be Published
6KJA	E. coli ATCase holoenzyme mutant - G128/130A (catalytic chain) 分子名称: Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Lei, Z, Zheng, J, Jia, Z.C. 登録日 2019-07-22 公開日 2020-03-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.064 Å) 主引用文献 New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
4FYY	E. coli Aspartate Transcarbamoylase Complexed with CTP, UTP, and Mg2+ 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Cockrell, G.M, Kantrowitz, E.R. 登録日 2012-07-05 公開日 2012-10-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9395 Å) 主引用文献 Metal Ion Involvement in the Allosteric Mechanism of Escherichia coli Aspartate Transcarbamoylase. Biochemistry, 51, 2012
6KJ8	E. coli ATCase holoenzyme mutant - G166P (catalytic chain) 分子名称: Aspartate carbamoyltransferase catalytic subunit, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Lei, Z, Zheng, J, Jia, Z.C. 登録日 2019-07-22 公開日 2020-03-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.011 Å) 主引用文献 New regulatory mechanism-based inhibitors of aspartate transcarbamoylase for potential anticancer drug development. Febs J., 287, 2020
1PX3	E. COLI (LACZ) BETA-GALACTOSIDASE (G794A) 分子名称: DIMETHYL SULFOXIDE, MAGNESIUM ION, SODIUM ION, ... 著者 Juers, D.H, Hakda, S, Matthews, B.W, Huber, R.E. 登録日 2003-07-02 公開日 2004-06-15 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural Basis for the Altered Activity of Gly794 Variants of Escherichia coli Beta-Galactosidase Biochemistry, 42, 2003
4DUX	E. coli (lacZ) beta-galactosidase (N460S) in complex with L-ribose 分子名称: Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... 著者 Wheatley, R.W, Lo, S, Janzcewicz, L.J, Dugdale, M.L, Huber, R.E. 登録日 2012-02-22 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural explanation for allolactose (lac operon inducer) synthesis by lacZ beta-galactosidase and the evolutionary relationship between allolactose synthesis and the lac repressor. J.Biol.Chem., 288, 2013
4PNU	E. coli sliding clamp in complex with (R)-6-bromo-9-(2-((R)-1-carboxy-2-phenylethylamino)-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid 分子名称: (2R)-6-bromo-9-(2-{[(1R)-1-carboxy-2-phenylethyl]amino}-2-oxoethyl)-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2014-02-21 公開日 2014-03-05 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Bacterial Sliding Clamp Inhibitors that Mimic the Sequential Binding Mechanism of Endogenous Linear Motifs. J.Med.Chem., 58, 2015

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