8P0D
 
 | | Human 14-3-3 sigma in complex with human MDM2 peptide | | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Roversi, P, Ward, J, Doveston, R, Kwon, H, Romartinez Alonso, B. | | 登録日 | 2023-05-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Characterizing the protein-protein interaction between MDM2 and 14-3-3 sigma ; proof of concept for small molecule stabilization.
J.Biol.Chem., 300, 2024
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8OWJ
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2-L2 | | 分子名称: | Amyloid-beta A4 protein | | 著者 | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | 登録日 | 2023-04-28 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8P64
 | | Co-crystal structure of PD-L1 with low molecular weight inhibitor | | 分子名称: | Programmed cell death 1 ligand 1, ~{N}-[[1-[(~{E})-2-(2-methyl-3-phenyl-phenyl)ethenyl]-1,2,3,4-tetrazol-5-yl]methyl]ethanamine | | 著者 | Plewka, J, Magiera-Mularz, K, van der Straat, R, Draijer, R, Surmiak, E, Butera, R, Land, L, Musielak, B, Domling, A. | | 登録日 | 2023-05-25 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.312 Å) | | 主引用文献 | 1,5-Disubstituted tetrazoles as PD-1/PD-L1 antagonists.
Rsc Med Chem, 15, 2024
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8P00
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8OZS
 | | Populus tremula stable protein 1 with N-terminal binding peptide extension with hemin | | 分子名称: | Stable protein 1 | | 著者 | Sklyar, J, Zeibaq, Y, Bachar, O, Yehezkeli, O, Adir, N. | | 登録日 | 2023-05-09 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Bioengineered Stable Protein 1-Hemin Complex with Enhanced Peroxidase-Like Catalytic Properties
Small Science, 2023
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8OVM
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2 | | 分子名称: | Amyloid-beta A4 protein | | 著者 | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | 登録日 | 2023-04-26 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OZO
 | | Populus tremula stable protein 1 with N-terminal binding peptide extension | | 分子名称: | Stable protein 1 | | 著者 | Sklyar, J, Zeibaq, Y, Bachar, O, Yehezkeli, O, Adir, N. | | 登録日 | 2023-05-09 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Bioengineered Stable Protein 1-Hemin Complex with Enhanced Peroxidase-Like Catalytic Properties
Small Science, 2024
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8OS5
 | | Crystal structure of the Factor XII heavy chain reveals an interlocking dimer with a FnII to kringle domain interaction | | 分子名称: | Coagulation factor XII-Mie | | 著者 | Li, C, Saleem, M, Kaira, B.G, Brown, A, Wilson, C, Philippou, H, Emsley, J. | | 登録日 | 2023-04-18 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery.
Blood, 136, 2020
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8OT9
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8OTD
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8OTG
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7A3S
 | | Crystal structure of dengue 3 virus envelope glycoprotein | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, SULFATE ION | | 著者 | Sharma, A, Vaney, M.C, Guardado-Calvo, P, Duquerroy, S, Rouvinski, A, Navarro-Sanchez, E, Rey, F.A. | | 登録日 | 2020-08-18 | | 公開日 | 2021-12-08 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses.
Cell, 184, 2021
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8OTH
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8OKP
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor AKI_33 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},15~{R})-10,13,15-trimethyl-17-oxidanylidene-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
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8OMC
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8P4Q
 | | Structure of the IMP dehydrogenase related protein GUAB3 from Synechocystis PCC 6803 | | 分子名称: | IMP dehydrogenase subunit, INOSINIC ACID, XANTHOSINE-5'-MONOPHOSPHATE | | 著者 | Hernandez-Gomez, A, Fernandez-Justel, D, Buey, R.M. | | 登録日 | 2023-05-23 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | GuaB3, an overlooked enzyme in cyanobacteria's toolbox that sheds light on IMP dehydrogenase evolution.
Structure, 31, 2023
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8OKA
 | | Human Mitochondrial Lon Y394F Mutant ADP Bound | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | | 著者 | Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E. | | 登録日 | 2023-03-28 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.89 Å) | | 主引用文献 | Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
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8OWE
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L2-L3 | | 分子名称: | Amyloid-beta A4 protein | | 著者 | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | 登録日 | 2023-04-27 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OKT
 | | Carbonic Anhydrase IX like mutant in Complex with Steriod_Sulphamoyl inhibitor VK42 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(8~{R},9~{S},13~{S},14~{S})-13-methyl-17-oxidanylidene-7,8,9,11,12,14,15,16-octahydro-6~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-29 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
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8P6U
 | | Human carbonic anhydrase II containing 5-fluorotryptophanes | | 分子名称: | BENZOIC ACID, Carbonic anhydrase 2, MERCURIBENZOIC ACID, ... | | 著者 | Pham, L.B.T, Costantino, A, Barbieri, L, Calderone, V, Luchinat, E, Banci, L. | | 登録日 | 2023-05-30 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Controlling the incorporation of fluorinated amino acids in human cells and its structural impact.
Protein Sci., 33, 2024
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8OMN
 | | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl VK4 | | 分子名称: | Carbonic anhydrase 2, ZINC ION, [(3~{R},5~{R},8~{R},9~{S},10~{S},13~{S},14~{S},17~{S})-17-ethanoyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-3-yl] sulfamate | | 著者 | Brynda, J, Rezacova, P.M, Kudova, E. | | 登録日 | 2023-03-31 | | 公開日 | 2024-04-10 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Carbonic Anhydrase II in Complex with Steriod_Sulphamoyl
To Be Published
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8OVK
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L1 | | 分子名称: | Amyloid-beta A4 protein | | 著者 | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | 登録日 | 2023-04-26 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OWK
 | | Lipidic amyloid-beta(1-40) fibril - polymorph L3-L3 | | 分子名称: | Amyloid-beta A4 protein | | 著者 | Frieg, B, Han, M, Giller, K, Dienemann, C, Riedel, D, Becker, S, Andreas, L.B, Griesinger, C, Schroeder, G.F. | | 登録日 | 2023-04-28 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Cryo-EM structures of lipidic fibrils of amyloid-beta (1-40).
Nat Commun, 15, 2024
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8OT6
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8ORR
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