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1XDI
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Crystal structure of LpdA (Rv3303c) from Mycobacterium tuberculosis
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Rv3303c-lpdA
著者Argyrou, A, Vetting, M.W, Blanchard, J.S.
登録日2004-09-06
公開日2004-10-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Characterization of a New Member of the Flavoprotein Disulfide Reductase Family of Enzymes from Mycobacterium tuberculosis
J.Biol.Chem., 279, 2004
1U5H
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BU of 1u5h by Molmil
Structure of Citrate Lyase beta subunit from Mycobacterium tuberculosis
分子名称: FORMIC ACID, citE
著者Goulding, C.W, Lekin, T, Kim, C.Y, Segelke, B, Terwilliger, T.C, Eisenberg, D, TB Structural Genomics Consortium (TBSGC)
登録日2004-07-27
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function.
J.Mol.Biol., 365, 2007
3EUL
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BU of 3eul by Molmil
Structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis
分子名称: CHLORIDE ION, POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-binding response regulator, LuxR family)
著者Schneider, G, Schnell, R, Agren, D.
登録日2008-10-10
公開日2008-11-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1.9 A structure of the signal receiver domain of the putative response regulator NarL from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.F, 64, 2008
3F69
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Crystal structure of the Mycobacterium tuberculosis PknB mutant kinase domain in complex with KT5720
分子名称: SULFATE ION, Serine/threonine-protein kinase pknB, hexyl (5S,6R,8R)-6-hydroxy-5-methyl-13-oxo-5,6,7,8-tetrahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]c yclopenta[e]-as-indacene-6-carboxylate
著者Alber, T, Mieczkowski, C.A, TB Structural Genomics Consortium (TBSGC)
登録日2008-11-05
公開日2008-12-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Auto-activation mechanism of the Mycobacterium tuberculosis PknB receptor Ser/Thr kinase.
Embo J., 27, 2008
7CAF
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BU of 7caf by Molmil
Mycobacterium smegmatis LpqY-SugABC complex in the pre-translocation state
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T, Rao, Z.
登録日2020-06-08
公開日2020-12-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
7CAG
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Mycobacterium smegmatis LpqY-SugABC complex in the catalytic intermediate state
分子名称: ABC sugar transporter, permease component, ABC transporter, ...
著者Liu, F, Liang, J, Zhang, B, Gao, Y, Yang, X, Hu, T.
登録日2020-06-08
公開日2020-12-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC.
Sci Adv, 6, 2020
7C6O
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Catalytic Subunit of Cobaltochelatase from Mycobacterium tuberculosis
分子名称: Cobalamin biosynthesis protein CobN, GLYCEROL, SODIUM ION
著者Zhang, J, Liu, L.
登録日2020-05-22
公開日2020-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Crystal structure of the large subunit of cobaltochelatase from Mycobacterium tuberculosis.
Proteins, 89, 2021
2NAF
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Solution structure of peptidyl-tRNA hydrolase from Mycobacterium smegmatis
分子名称: Peptidyl-tRNA hydrolase
著者Yadav, R, Pathak, P, Fatma, F, Kabra, A, Pulavarti, S, Jain, A, Kumar, A, Shukla, V, Arora, A.
登録日2015-12-23
公開日2017-01-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural characterization of peptidyl-tRNA hydrolase from Mycobacterium smegmatis by NMR spectroscopy.
Biochim.Biophys.Acta, 1864, 2016
3IJF
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Crystal structure of cytidine deaminase from Mycobacterium tuberculosis
分子名称: Cytidine deaminase, ZINC ION
著者De Azevedo Jr, W.F, Basso, L.A, Santos, D.S.
登録日2009-08-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase.
J.Struct.Biol., 169, 2010
3IOM
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BU of 3iom by Molmil
Crystal structure of Purine Nucleoside Phosphorylase from Mycobacterium tuberculosis in complex with 2'-Deoxyguanosine
分子名称: 2'-DEOXY-GUANOSINE, Purine nucleoside phosphorylase, SULFATE ION
著者de Azevedo Jr, W.F, Basso, L.A, Santos, D.S.
登録日2009-08-14
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis.
Bioorg.Med.Chem., 18, 2010
1YS6
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Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis
分子名称: CALCIUM ION, GLYCEROL, Transcriptional regulatory protein prrA
著者Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-07
公開日2006-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Crystal structure of the response regulatory protein PrrA from Mycobacterium Tuberculosis
To be published
3X3M
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Crystal structure of EccB1 of Mycobacterium tuberculosis in spacegroup P212121
分子名称: CALCIUM ION, ESX-1 secretion system protein EccB1
著者Zhang, X.L, Li, D.F, Zhang, X.E, Bi, L.J, Wang, D.C.
登録日2015-01-24
公開日2015-12-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Core component EccB1 of the Mycobacterium tuberculosis type VII secretion system is a periplasmic ATPase.
Faseb J., 29, 2015
7CF8
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PfkB(Mycobacterium marinum)
分子名称: Fructokinase, PfkB, GLYCEROL, ...
著者Li, J, Gao, B, Ji, R.
登録日2020-06-24
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural analysis and functional study of phosphofructokinase B (PfkB) from Mycobacterium marinum.
Biochem.Biophys.Res.Commun., 579, 2021
1X74
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Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis- mutational and structural characterization of the fold and active site
分子名称: 2-methylacyl-CoA racemase, GLYCEROL, PHOSPHATE ION
著者Kalle, S, Bhaumik, P, Schmitz, W, Kotti, T.J, Conzelmann, E, Wierenga, R.K, Hiltunen, J.K.
登録日2004-08-13
公開日2005-01-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献{alpha}-Methylacyl-CoA Racemase from Mycobacterium tuberculosis: MUTATIONAL AND STRUCTURAL CHARACTERIZATION OF THE ACTIVE SITE AND THE FOLD
J.Biol.Chem., 280, 2005
1YSR
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Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Sensor-type histidine kinase prrB
著者Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-09
公開日2005-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of ATP binding domain of PrrB from Mycobacterium Tuberculosis
To be published
1YS7
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Crystal structure of the response regulator protein prrA complexed with Mg2+
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ...
著者Nowak, E, Panjikar, S, Tucker, P, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-02-07
公開日2006-02-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis.
J.Biol.Chem., 281, 2006
4LJ1
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RipD (Rv1566c) from Mycobacterium tuberculosis: a non-catalytic NlpC/p60 domain protein with two penta-peptide repeat units (PVQQA-PVQPA)
分子名称: Invasion-associated protein
著者Both, D, Steiner, E.M, Linder, D.C, Schnell, R, Schneider, G.
登録日2013-07-04
公開日2013-11-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献RipD (Rv1566c) from Mycobacterium tuberculosis: adaptation of an NlpC/p60 domain to a non-catalytic peptidoglycan-binding function.
Biochem.J., 457, 2014
1ZEL
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BU of 1zel by Molmil
Crystal structure of RV2827C protein from Mycobacterium tuberculosis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, FORMIC ACID, ...
著者Janowski, R, Panjikar, S, Mueller-dieckmann, J, Weiss, M.S, TB Structural Genomics Consortium (TBSGC)
登録日2005-04-19
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis.
J Struct Funct Genomics, 10, 2009
2XT6
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Crystal structure of Mycobacterium smegmatis alpha-ketoglutarate decarboxylase homodimer (orthorhombic form)
分子名称: 2-OXOGLUTARATE DECARBOXYLASE, CALCIUM ION, MAGNESIUM ION, ...
著者Wagner, T, Bellinzoni, M, Wehenkel, A.M, O'Hare, H.M, Alzari, P.M.
登録日2010-10-05
公開日2011-06-15
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism.
Chem.Biol., 18, 2011
2IRX
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Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D with GTP and Manganese.
分子名称: DNA ligase-like protein Rv0938/MT0965, GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION
著者Brissett, N.C, Pitcher, R.S, Doherty, A.J.
登録日2006-10-16
公開日2007-01-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of a mycobacterial NHEJ DNA repair polymerase.
J.Mol.Biol., 366, 2007
3FSY
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BU of 3fsy by Molmil
Structure of tetrahydrodipicolinate N-succinyltransferase (Rv1201c;DapD) in complex with succinyl-CoA from Mycobacterium tuberculosis
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, MAGNESIUM ION, ...
著者Schuldt, L, Weyand, S, Kefala, G, Weiss, M.S.
登録日2009-01-12
公開日2009-06-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献The three-dimensional Structure of a mycobacterial DapD provides insights into DapD diversity and reveals unexpected particulars about the enzymatic mechanism.
J.Mol.Biol., 389, 2009
4CHG
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BU of 4chg by Molmil
Crystal structure of VapBC15 complex from Mycobacterium tuberculosis
分子名称: ANTITOXIN VAPB15, MAGNESIUM ION, MANGANESE (II) ION, ...
著者Das, U, Pogenberg, V, Tiruttani Subhramanyam, U.K, Wilmanns, M, Srinivasan, A, Gourinath, S.
登録日2013-12-02
公開日2014-11-12
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Vapbc-15 Complex from Mycobacterium Tuberculosis Reveals a Two-Metal Ion Dependent Pin-Domain Ribonuclease And a Variable Mode of Toxin-Antitoxin Assembly.
J.Struct.Biol., 188, 2014
2OZ5
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Crystal structure of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB in complex with the specific inhibitor OMTS
分子名称: Phosphotyrosine protein phosphatase ptpb, {(3-CHLOROBENZYL)[(5-{[(3,3-DIPHENYLPROPYL)AMINO]SULFONYL}-2-THIENYL)METHYL]AMINO}(OXO)ACETIC ACID
著者Grundner, C, Gee, C.L, Alber, T, TB Structural Genomics Consortium (TBSGC)
登録日2007-02-23
公開日2007-05-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB.
Structure, 15, 2007
4JD6
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Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin
分子名称: COENZYME A, Enhanced intracellular survival protein, TOBRAMYCIN
著者Biswas, T, Chen, W, Garneau-Tsodikova, S, Tsodikov, O.V.
登録日2013-02-23
公開日2013-10-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Chemical and structural insights into the regioversatility of the aminoglycoside acetyltransferase eis.
Chembiochem, 14, 2013
4NQW
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Structure of Mycobacterium tuberculosis extracytoplasmic function sigma factor SigK in complex with the cytosolic domain of its cognate anti-sigma factor RskA
分子名称: Anti-sigma-K factor RskA, CADMIUM ION, ECF RNA polymerase sigma factor SigK
著者Shukla, J.K, Gopal, B.
登録日2013-11-25
公開日2014-01-22
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the redox sensitivity of the Mycobacterium tuberculosis SigK-RskA sigma-anti-sigma complex
Acta Crystallogr.,Sect.D, 70, 2014

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