1TQF
 
 | | Crystal structure of human Beta secretase complexed with inhibitor | | 分子名称: | 3-{2-[(5-AMINOPENTYL)AMINO]-2-OXOETHOXY}-5-({[1-(4-FLUOROPHENYL)ETHYL]AMINO}CARBONYL)PHENYL PHENYLMETHANESULFONATE, Beta-secretase 1 | | 著者 | Munshi, S, Chen, Z, Kuo, L. | | 登録日 | 2004-06-17 | | 公開日 | 2004-11-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification of a small molecule nonpeptide active site beta-secretase inhibitor that displays a nontraditional binding mode for aspartyl proteases.
J.Med.Chem., 47, 2004
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1TQG
 | | CheA phosphotransferase domain from Thermotoga maritima | | 分子名称: | Chemotaxis protein cheA | | 著者 | Quezada, C.M, Gradinaru, C, Simon, M.I, Bilwes, A.M, Crane, B.R. | | 登録日 | 2004-06-17 | | 公開日 | 2004-09-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Helical Shifts Generate Two Distinct Conformers in the Atomic Resolution Structure of the CheA Phosphotransferase Domain from Thermotoga maritima.
J.Mol.Biol., 341, 2004
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1TQH
 | | Covalent Reaction intermediate Revealed in Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est30 | | 分子名称: | Carboxylesterase precursor, PROPYL ACETATE, SULFATE ION | | 著者 | Liu, P, Wang, Y.F, Ewis, H.E, Abdelal, A.T, Lu, C.D, Harrison, R.W, Weber, I.T. | | 登録日 | 2004-06-17 | | 公開日 | 2004-09-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Covalent reaction intermediate revealed in crystal structure of the Geobacillus stearothermophilus carboxylesterase Est30.
J.Mol.Biol., 342, 2004
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1TQI
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1TQJ
 | | Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution | | 分子名称: | Ribulose-phosphate 3-epimerase | | 著者 | Wise, E.L, Akana, J, Gerlt, J.A, Rayment, I. | | 登録日 | 2004-06-17 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
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1TQL
 | | POLIOVIRUS POLYMERASE G1A MUTANT | | 分子名称: | ACETIC ACID, RNA-directed RNA polymerase | | 著者 | Thompson, A.A, Peersen, O.B. | | 登録日 | 2004-06-17 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23, 2004
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1TQM
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1TQN
 | | Crystal Structure of Human Microsomal P450 3A4 | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 3A4 | | 著者 | Yano, J.K, Wester, M.R, Schoch, G.A, Griffin, K.J, Stout, C.D, Johnson, E.F. | | 登録日 | 2004-06-17 | | 公開日 | 2004-07-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-A Resolution
J.Biol.Chem., 279, 2004
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1TQO
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1TQP
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1TQQ
 | | Structure of TolC in complex with hexamminecobalt | | 分子名称: | COBALT HEXAMMINE(III), Outer membrane protein tolC | | 著者 | Higgins, M.K, Eswaran, J, Edwards, P.C, Schertler, G.F, Hughes, C, Koronakis, V. | | 登録日 | 2004-06-18 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug effllux protein TolC
J.Mol.Biol., 342, 2004
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1TQR
 | | NMR Structure of DNA 17-mer GGAAAATCTCTAGCAGT corresponding to the extremity of the U5 LTR of the HIV-1 genome | | 分子名称: | DNA HIV-1 U5 LTR extremity | | 著者 | Renisio, J.G, Cosquer, S, Cherrak, I, El Antri, S, Mauffret, O, Fermandjian, S. | | 登録日 | 2004-06-18 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase
NUCLEIC ACIDS RES., 33, 2005
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1TQS
 | | Golgi alpha-Mannosidase II In Complex With Salacinol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIDEOXY-1,4-[[2S,3S)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISULFONIUMYLIDENE]-D-ARABINITOL INNER SALT, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Ghavami, A, Johnston, B.D, Pinto, B.M, Rose, D.R. | | 登録日 | 2004-06-18 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
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1TQT
 | | Golgi alpha-Mannosidase II In Complex With A Diastereomer of Salacinol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIDEOXY-1,4-[[2R,3R)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISULFONIUMYLIDENE]-D-ARABINITOL INNER SALT, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Ghavami, A, Johnston, B.D, Pinto, B.M, Rose, D.R. | | 登録日 | 2004-06-18 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
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1TQU
 | | Golgi alpha-Mannosidase II In Complex With The Salacinol Analog Ghavamiol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1'-((1,4-DIDEOXY-1,4-IMINO-D-ARABINITOL)-4-N-AMMONIUM)-1'-DEOXY-L-ERYTHRITOL-3'-SULFATE INNER SALT, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Ghavami, A, Johnston, B.D, Pinto, B.M, Rose, D.R. | | 登録日 | 2004-06-18 | | 公開日 | 2005-01-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues
Tetrahedron Asymmetry, 16, 2005
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1TQV
 | | Golgi alpha-Mannosidase II In Complex With Seleno-Salacinol (Blintol) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIDEOXY-1,4-[[2S,3S)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISELENONIUMYLIDENE]-D-ARABINITOL INNER SALT, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Ghavami, A, Johnston, B.D, Pinto, B.M, Rose, D.R. | | 登録日 | 2004-06-18 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Crystallographic analysis of the interactions of Drosophila melanogaster Golgi alpha-mannosidase II
with the naturally occurring glycomimetic salacinol and its analogues
TETRAHEDRON ASYMMETRY, 16, 2005
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1TQW
 | | Golgi alpha-Mannosidase II In Complex With A Diastereomer of Seleno-Salacinol | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIDEOXY-1,4-[[2R,3R)-2,4-DIHYDROXY-3-(SULFOXY)BUTYL]EPISELENONIUMYLIDENE]-D-ARABINITOL INNER SALT, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kuntz, D.A, Ghavami, A, Johnston, B.D, Pinto, B.M, Rose, D.R. | | 登録日 | 2004-06-18 | | 公開日 | 2005-02-01 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Insights into the Mechanism of Drosophila melanogaster Golgi a-Mannosidase II Through Crystallographic Analysis of the Interactions with Analogues of the Naturally Occurring Glycomimetic Salacinol
TETRAHEDRON ASYMMETRY, 16, 2005
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1TQX
 | | Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum | | 分子名称: | D-ribulose-5-phosphate 3-epimerase, putative, SULFATE ION, ... | | 著者 | Caruthers, J, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | | 登録日 | 2004-06-18 | | 公開日 | 2004-12-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum.
Proteins, 62, 2006
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1TQY
 | | The Actinorhodin Ketosynthase/Chain Length Factor | | 分子名称: | ACETYL GROUP, Actinorhodin polyketide putative beta-ketoacyl synthase 1, Actinorhodin polyketide putative beta-ketoacyl synthase 2, ... | | 著者 | Keatinge-Clay, A.T, Maltby, D.A, Medzihradszky, K.F, Khosla, C, Stroud, R.M. | | 登録日 | 2004-06-18 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An antibiotic factory caught in action.
Nat.Struct.Mol.Biol., 11, 2004
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1TQZ
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1TR0
 | | Crystal Structure of a boiling stable protein SP1 | | 分子名称: | GLYCEROL, stable protein 1 | | 著者 | Almog, O, Gonzalez, A, Sofer, O, Dgany, O, Shoseyov, O. | | 登録日 | 2004-06-18 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structural basis of the thermostability of SP1, a novel plant (Populus tremula) boiling stable protein
J.Biol.Chem., 279, 2004
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1TR1
 | | CRYSTAL STRUCTURE OF E96K MUTATED BETA-GLUCOSIDASE A FROM BACILLUS POLYMYXA, AN ENZYME WITH INCREASED THERMORESISTANCE | | 分子名称: | BETA-GLUCOSIDASE A, GLYCEROL | | 著者 | Sanz-Aparicio, J, Hermoso, J.A, Martinez-Ripoll, M, Gonzalez-Perez, B, Polaina, J. | | 登録日 | 1998-03-12 | | 公開日 | 1999-04-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of beta-glucosidase A from Bacillus polymyxa: insights into the catalytic activity in family 1 glycosyl hydrolases.
J.Mol.Biol., 275, 1998
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1TR2
 | | Crystal structure of human full-length vinculin (residues 1-1066) | | 分子名称: | VINCULIN ISOFORM 1 | | 著者 | Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T. | | 登録日 | 2004-06-19 | | 公開日 | 2005-11-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of Human Vinculin
Structure, 12, 2004
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1TR4
 | | Solution structure of human oncogenic protein gankyrin | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10 | | 著者 | Yuan, C, Li, J, Mahajan, A, Poi, M.J, Byeon, I.J, Tsai, M.D. | | 登録日 | 2004-06-19 | | 公開日 | 2004-11-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.
Biochemistry, 43, 2004
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1TR5
 | | Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E | | 分子名称: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | 著者 | Nguyen, D.M, Leila Reynald, R, Gittis, A.G, Lattman, E.E. | | 登録日 | 2004-06-20 | | 公開日 | 2004-07-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior
J.Mol.Biol., 341, 2004
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