4WLU
 
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1UWR
 | | Structure of beta-glycosidase from Sulfolobus solfataricus in complex with 2-deoxy-2-fluoro-galactose | | 分子名称: | 2-deoxy-2-fluoro-alpha-D-galactopyranose, ACETATE ION, BETA-GALACTOSIDASE | | 著者 | Gloster, T.M, Roberts, S, Ducros, V.M.-A, Perugino, G, Rossi, M, Hoos, R, Moracci, M, Vasella, A, Davies, G.J. | | 登録日 | 2004-02-11 | | 公開日 | 2004-05-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural Studies of the Beta-Glycosidase from Sulfolobus Solfataricus in Complex with Covalently and Noncovalently Bound Inhibitors.
Biochemistry, 43, 2004
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1GAD
 | | COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY | | 分子名称: | D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O. | | 登録日 | 1995-10-24 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
J.Mol.Biol., 257, 1996
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1UXQ
 | | Structural basis for allosteric regulation and substrate specificity of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase (GAPN) from Thermoproteus tenax | | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (NADP+), NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Lorentzen, E, Hensel, R, Pohl, E. | | 登録日 | 2004-03-01 | | 公開日 | 2004-08-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of Allosteric Regulation and Substrate Specificity of the Non-Phosphorylating Glyceraldehyde 3-Phosphate Dehydrogenase from Thermoproteus Tenax
J.Mol.Biol., 341, 2004
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3OX2
 | | X-ray Structural study of quinone reductase II inhibition by compounds with micromolar to nanomolar range IC50 values | | 分子名称: | 2-hydroxy-8,9-dimethoxy-6H-isoindolo[2,1-a]indol-6-one, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | | 著者 | Pegan, S.D, Sturdy, M, Mesecar, A.D. | | 登録日 | 2010-09-21 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | X-ray structural studies of quinone reductase 2 nanomolar range inhibitors.
Protein Sci., 20, 2011
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1UJN
 | | Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8 | | 分子名称: | dehydroquinate synthase | | 著者 | Sugahara, M, Yokoyama, S, Kuramitsu, S, Miyano, M, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-08-06 | | 公開日 | 2003-09-02 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of dehydroquinate synthase from Thermus thermophilus HB8 showing functional importance of the dimeric state.
Proteins, 58, 2005
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7F5T
 | | Drosophila P5CS filament with glutamate | | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase, GLUTAMIC ACID | | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | | 登録日 | 2021-06-22 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural basis of dynamic P5CS filaments.
Elife, 11, 2022
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1GB3
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-06-26 | | 公開日 | 2000-07-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
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1UJM
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1GB8
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-06-26 | | 公開日 | 2000-07-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
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7EUL
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1GBZ
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-06-26 | | 公開日 | 2000-07-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
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1V3H
 | | The roles of Glu186 and Glu380 in the catalytic reaction of soybean beta-amylase | | 分子名称: | Beta-amylase, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | 著者 | Kang, Y.N, Adachi, M, Utsumi, S, Mikami, B. | | 登録日 | 2003-11-02 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Roles of Glu186 and Glu380 in the Catalytic Reaction of Soybean beta-Amylase.
J.Mol.Biol., 339, 2004
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1GB0
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-06-26 | | 公開日 | 2000-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions.
Biochemistry, 39, 2000
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1V3V
 | | Crystal structure of leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase complexed with NADP and 15-oxo-PGE2 | | 分子名称: | (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Hori, T, Yokomizo, T, Ago, H, Sugahara, M, Ueno, G, Yamamoto, M, Kumasaka, T, Shimizu, T, Miyano, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-11-06 | | 公開日 | 2004-07-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of leukotriene B4 12-hydroxydehydrogenase/15-Oxo-prostaglandin 13-reductase catalytic mechanism and a possible Src homology 3 domain binding loop
J.Biol.Chem., 279, 2004
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1GED
 | | A positive charge route for the access of nadh to heme formed in the distal heme pocket of cytochrome p450nor | | 分子名称: | BROMIDE ION, CYTOCHROME P450 55A1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Kudo, T, Takaya, N, Park, S.-Y, Shiro, Y, Shoun, H. | | 登録日 | 2000-11-02 | | 公開日 | 2000-11-22 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH
J.Biol.Chem., 276, 2001
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5K0Z
 | | Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state | | 分子名称: | L-lactate dehydrogenase B chain | | 著者 | Merk, A, Bartesaghi, A, Banerjee, S, Falconieri, V, Rao, P, Earl, L, Milne, J, Subramaniam, S. | | 登録日 | 2016-05-17 | | 公開日 | 2016-06-08 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
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1GG5
 | | CRYSTAL STRUCTURE OF A COMPLEX OF HUMAN NAD[P]H-QUINONE OXIDOREDUCTASE AND A CHEMOTHERAPEUTIC DRUG (E09) AT 2.5 A RESOLUTION | | 分子名称: | 3-HYDROXYMETHYL-5-AZIRIDINYL-1METHYL-2-[1H-INDOLE-4,7-DIONE]-PROPANOL, FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H DEHYDROGENASE [QUINONE] 1 | | 著者 | Faig, M, Bianchet, M.A, Winski, S, Hargreaves, R, Moody, C.J, Hudnott, A.R, Ross, D, Amzel, L.M. | | 登録日 | 2000-07-12 | | 公開日 | 2001-09-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based development of anticancer drugs: complexes of NAD(P)H:quinone oxidoreductase 1 with chemotherapeutic quinones.
Structure, 9, 2001
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1V6X
 | | Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose | | 分子名称: | 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ... | | 著者 | Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. | | 登録日 | 2003-12-04 | | 公開日 | 2004-04-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
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1GFA
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-12-04 | | 公開日 | 2000-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
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1GFK
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-12-04 | | 公開日 | 2000-12-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
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5K2S
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1GFU
 | | CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS | | 分子名称: | LYSOZYME, SODIUM ION | | 著者 | Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. | | 登録日 | 2000-12-04 | | 公開日 | 2000-12-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Positive contribution of hydration structure on the surface of human lysozyme to the conformational stability.
J.Biol.Chem., 277, 2002
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7EUK
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4LDO
 | | Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody | | 分子名称: | (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, Camelid Antibody Fragment, L-EPINEPHRINE, ... | | 著者 | Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. | | 登録日 | 2013-06-24 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody.
Nature, 502, 2013
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