PDB: 46006 件ウェブページステータス検索Chemie searchBIRD

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6EJZ	Tryptophan Repressor TrpR from E.coli variant S88Y with Indole-3-acetic acid as ligand 分子名称: 1,2-ETHANEDIOL, 1H-INDOL-3-YLACETIC ACID, SULFATE ION, ... 著者 Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. 登録日 2017-09-24 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A biosensor for the direct visualization of auxin Nature, 2021
6ELF	Tryptophan Repressor TrpR from E.coli variant M42F T44L T81I S88Y with Indole-3-acetic acid as ligand 分子名称: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. 登録日 2017-09-28 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.832 Å) 主引用文献 A biosensor for the direct visualization of auxin Nature, 2021
5MTY	Dibenzosuberone inhibitor 8e in complex with p38 MAPK 分子名称: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, ~{N}-[2,4-bis(fluoranyl)-5-[[14-(2-hydroxyethylcarbamoyl)-2-oxidanylidene-6-tricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaenyl]amino]phenyl]thiophene-2-carboxamide 著者 Buehrmann, M, Rauh, D. 登録日 2017-01-11 公開日 2017-09-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Design, Synthesis, and Biological Evaluation of Novel Type I(1)/2 p38 alpha MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine. J. Med. Chem., 60, 2017
6EKP	Tryptophan Repressor TrpR from E.coli variant T44L T81M S88Y with Indole-3-acetic acid as ligand 分子名称: 1H-INDOL-3-YLACETIC ACID, 3,6,9,12,15-PENTAOXAHEPTADECANE, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. 登録日 2017-09-26 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 A biosensor for the direct visualization of auxin Nature, 2021
6ENN	Tryptophan Repressor TrpR from E.coli variant T44L T81M N87G S88Y with Indole-3-acetic acid as ligand 分子名称: 1H-INDOL-3-YLACETIC ACID, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Herud-Sikimic, O, Juergens, G, Hocker, B. 登録日 2017-10-05 公開日 2019-02-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 A biosensor for the direct visualization of auxin Nature, 2021
5XS9	Crystal structure of Mycobacterium smegmatis BioQ 分子名称: TetR family transcriptional regulator 著者 Zhang, Y, Ji, Q, Feng, Y. 登録日 2017-06-13 公開日 2018-06-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of BioQ suggests a distinct regulatory mechanism for biotin, a nutritional virulence factor in Mycobacterium To Be Published
6P5J	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
6P5I	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-02-26 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
5N65	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9h 分子名称: 2-phenyl-~{N}4-(2-thiophen-2-ylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N64	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9g 分子名称: 2-phenyl-~{N}4-(thiophen-2-ylmethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
6P5N	Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-25 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
5MZ3	P38 ALPHA MUTANT C162S IN COMPLEX WITH CMPD2 [N-(4-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-(trifluoromethyl)benzamide] 分子名称: Mitogen-activated protein kinase 14, ~{N}-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methyl-phenyl]-3-(trifluoromethyl)benzamide 著者 Cowan-Jacob, S.W, Scheufler, C. 登録日 2017-01-30 公開日 2017-11-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
6YBS	Structure of a human 48S translational initiation complex - head 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S12, ... 著者 Brito Querido, J, Sokabe, M, Kraatz, S, Gordiyenko, Y, Skehel, M, Fraser, C, Ramakrishnan, V. 登録日 2020-03-17 公開日 2020-09-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of a human 48Stranslational initiation complex. Science, 369, 2020
5N66	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9j 分子名称: 1-(5-TERT-BUTYL-2-P-TOLYL-2H-PYRAZOL-3-YL)-3-[4-(2-MORPHOLIN-4-YL-ETHOXY)-NAPHTHALEN-1-YL]-UREA, Mitogen-activated protein kinase 14, ~{N}4-[[4-(cyclopropylmethyl)furan-2-yl]methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Wiedemann, B, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
6FAL	Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand 分子名称: INDOLYLPROPIONIC ACID, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Hocker, B. 登録日 2017-12-15 公開日 2019-01-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Tryptophan Repressor TrpR from E.coli: A ligand binding study To Be Published
6F7F	Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid 分子名称: INDOLYLPROPIONIC ACID, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Hocker, B. 登録日 2017-12-08 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.128 Å) 主引用文献 Tryptophan Repressor TrpR: A study of ligand binding specificity To Be Published
6P5K	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
6F7G	Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine 分子名称: 2-(5-methyl-1~{H}-indol-3-yl)ethanamine, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Hocker, B. 登録日 2017-12-08 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.656 Å) 主引用文献 Tryptophan Repressor TrpR: A ligand specificity study To Be Published
6F9K	Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand 分子名称: 5-methyl-L-tryptophan, SULFATE ION, Trp operon repressor 著者 Stiel, A.C, Shanmugaratnam, S, Hocker, B. 登録日 2017-12-14 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.399 Å) 主引用文献 Tryptophan Repressor TrpR from E.coli: A ligand binding study To Be Published
5AFI	2.9A Structure of E. coli ribosome-EF-TU complex by cs-corrected cryo-EM 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fischer, N, Neumann, P, Konevega, A.L, Bock, L.V, Ficner, R, Rodnina, M.V, Stark, H. 登録日 2015-01-22 公開日 2015-03-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structure of the E. coli ribosome-EF-Tu complex at <3 angstrom resolution by Cs-corrected cryo-EM. Nature, 520, 2015
5N67	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9l 分子名称: 1-[4-[4-[7-azanyl-4-(2-phenylethylamino)quinazolin-2-yl]phenyl]piperazin-1-yl]ethanone, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N68	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9m 分子名称: 2-(4-morpholin-4-ylphenyl)-~{N}4-(2-phenylethyl)quinazoline-4,7-diamine, Mitogen-activated protein kinase 14 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
5N63	Crystal Structure of p38alpha in Complex with Lipid Pocket Ligand 9c 分子名称: Mitogen-activated protein kinase 14, ~{N}4-[(4-fluorophenyl)methyl]-2-phenyl-quinazoline-4,7-diamine 著者 Buehrmann, M, Mueller, M.P, Rauh, D. 登録日 2017-02-14 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38 alpha MAPK. PLoS ONE, 12, 2017
6C4I	Conformation of methylated GGQ in the peptidyl transferase center during translation termination 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Zeng, F, Jin, H. 登録日 2018-01-12 公開日 2018-02-21 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.24 Å) 主引用文献 Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination. Sci Rep, 8, 2018
6BU8	70S ribosome with S1 domains 1 and 2 (Class 1) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... 著者 Loveland, A.B, Korostelev, A.A. 登録日 2017-12-08 公開日 2018-01-31 最終更新日 2020-01-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural dynamics of protein S1 on the 70S ribosome visualized by ensemble cryo-EM. Methods, 137, 2018

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