4JHB
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6J6V
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4JGM
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1JHH
| LEXA S119A MUTANT | 分子名称: | LEXA REPRESSOR, SULFATE ION | 著者 | Luo, Y, Pfuetzner, R.A, Mosimann, S, Little, J.W, Strynadka, N.C.J. | 登録日 | 2001-06-27 | 公開日 | 2001-09-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of LexA: a conformational switch for regulation of self-cleavage. Cell(Cambridge,Mass.), 106, 2001
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3BT9
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3BTI
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3BR3
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7KD8
| TtgR C137I I141W M167L F168Y mutant in complex with resveratrol | 分子名称: | HTH-type transcriptional regulator TtgR, MAGNESIUM ION, RESVERATROL | 著者 | Bingman, C.A, Nishikawa, K.K, Smith, R.W, Raman, S. | 登録日 | 2020-10-08 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Epistasis shapes the fitness landscape of an allosteric specificity switch. Nat Commun, 12, 2021
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3BR1
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3BTC
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3BTJ
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3BR6
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3BR5
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3BTL
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3BR2
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3BR0
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3BQZ
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2YR2
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7ZP8
| 70S E. coli ribosome with a stalled filamin domain 5 nascent chain | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Chan, S.H.S, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-26 | 公開日 | 2022-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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7ZQ6
| 70S E. coli ribosome with truncated uL23 and uL24 loops and a stalled filamin domain 5 nascent chain | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-29 | 公開日 | 2022-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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7ZOD
| 70S E. coli ribosome with an extended uL23 loop from Candidatus marinimicrobia | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Plessa, E, Wlodarski, T, Ahn, M, Sidhu, H, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-25 | 公開日 | 2022-08-10 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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7ZQ5
| 70S E. coli ribosome with truncated uL23 and uL24 loops | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Mitropoulou, A, Wlodarski, T, Ahn, M, Becker, T.A, Beckmann, R, Cabrita, L.D, Christodoulou, J. | 登録日 | 2022-04-29 | 公開日 | 2022-08-10 | 最終更新日 | 2024-11-13 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Modulating co-translational protein folding by rational design and ribosome engineering. Nat Commun, 13, 2022
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8FRQ
| LSD1-CoREST in complex with T14, long soaking | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(4aS)-7,8-dimethyl-5-(3-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl}propanoyl)-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2023-01-08 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 to be published
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8FRV
| LSD1-CoREST in complex with T17, short soaking | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-[3-(dimethylcarbamoyl)phenyl]-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2023-01-09 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 To be published
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8FRI
| LSD1-CoREST in complex with AW4, short soaking | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(1R,3S,3aS,13R)-1-hydroxy-10,11-dimethyl-4,6-dioxo-3-([1~1~,2~1~:2~3~,3~1~-terphenyl]-1~4~-yl)-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate (non-preferred name) | 著者 | Caroli, J, Mattevi, A. | 登録日 | 2023-01-07 | 公開日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1 To Be Published
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