PDB: 37722 件ウェブページステータス検索Chemie searchBIRD

---

4AHA	Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with fucosylated monosaccharides (Fuc1-2Gal, Fuc1- 3GlcNAc, Fuc1-4GlcNAc and Fuc1-6GlcNAc) 分子名称: Fucose-specific lectin, alpha-L-fucopyranose, alpha-L-fucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Houser, J, Komarek, J, Kostlanova, N, Lahmann, M, Cioci, G, Varrot, A, Imberty, A, Wimmerova, M. 登録日 2012-02-06 公開日 2013-02-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent Acta Crystallogr.,Sect.D, 71, 2015
8BOH	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 8 分子名称: 4-methyl-~{N}-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide, Ephrin type-A receptor 2 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
1FIT	FHIT (FRAGILE HISTIDINE TRIAD PROTEIN) 分子名称: FRAGILE HISTIDINE PROTEIN, SULFATE ION, beta-D-fructofuranose 著者 Lima, C.D, D'Amico, K.L, Naday, I, Rosenbaum, G, Westbrook, E.M, Hendrickson, W.A. 登録日 1997-05-17 公開日 1997-11-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family. Structure, 5, 1997
6Y03	Structure of Human Aldose Reductase Mutant L300/301A with a Citrate Molecule Bound in the Anion Binding Pocket 分子名称: Aldo-keto reductase family 1 member B1, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Hubert, L.-S, Ley, M, Heine, A, Klebe, G. 登録日 2020-02-06 公開日 2021-02-17 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structure of Human Aldose Reductase Mutant L300/301A with a Citrate Molecule Bound in the Anion Binding Pocket To Be Published
8BOF	Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with Compound 12 分子名称: 4-methyl-~{N}-(3-methylphenyl)-3-[(1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-yl)amino]benzamide, Ephrin type-A receptor 2 著者 Linhard, V, Witt, K, Gande, S, Wollenhaupt, J, Lennartz, F, Weiss, M.S, Schwalbe, H. 登録日 2022-11-15 公開日 2023-03-08 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Optimization of the Lead Compound NVP-BHG712 as a Colorectal Cancer Inhibitor. Chemistry, 29, 2023
3MB9	Human Aldose Reductase mutant T113A complexed with Zopolrestat 分子名称: 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Koch, C, Heine, A, Klebe, G. 登録日 2010-03-25 公開日 2011-03-09 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Ligand-induced fit affects binding modes and provokes changes in crystal packing of aldose reductase Biochim.Biophys.Acta, 1810, 2011
7LHE	Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION 著者 Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. 登録日 2021-01-22 公開日 2021-06-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
3FR5	N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors 分子名称: 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid, Fatty acid-binding protein, adipocyte 著者 Barf, T, Hammer, K, Lehmann, F, Haile, S, Axen, E, Medina, C, Uppenberg, J, Svensson, S, Rondahl, L, Lundb ck, T. 登録日 2009-01-08 公開日 2009-03-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. Bioorg.Med.Chem.Lett., 19, 2009
7LHF	Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state 分子名称: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION 著者 Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I. 登録日 2021-01-22 公開日 2021-06-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Cryo-EM structure of type 1 IP3R channel in a lipid bilayer Commun Biol, 4, 2021
3MC5	Human Aldose Reductase mutant T113V in complex with IDD393 crystallized in spacegroup P1 分子名称: (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Koch, C, Heine, A, Klebe, G. 登録日 2010-03-27 公開日 2011-03-09 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Ligand-induced fit affects binding modes and provokes changes in crystal packing of aldose reductase Biochim.Biophys.Acta, 1810, 2011
3S4R	Crystal structure of vimentin coil1A/1B fragment with a stabilizing mutation 分子名称: GLYCEROL, Vimentin 著者 Chernyatina, A.A, Strelkov, S.V. 登録日 2011-05-20 公開日 2012-08-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.452 Å) 主引用文献 Atomic structure of the vimentin central alpha-helical domain and its implications for intermediate filament assembly. Proc.Natl.Acad.Sci.USA, 109, 2012
1XQ0	Structure of human carbonic anhydrase II with 4-[(3-bromo-4-O-sulfamoylbenzyl)(4-cyanophenyl)amino]-4H-[1,2,4]-triazole 分子名称: 2-BROMO-4-{[(4-CYANOPHENYL)(4H-1,2,4-TRIAZOL-4-YL)AMINO]METHYL}PHENYL SULFAMATE, Carbonic anhydrase II, ZINC ION 著者 Lloyd, M.D, Thiyagarajan, N, Ho, Y.T, Woo, L.W.L, Sutcliffe, O.B, Purohit, A, Reed, M.J, Acharya, K.R, Potter, B.V.L. 登録日 2004-10-11 公開日 2005-05-17 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 First Crystal Structures of Human Carbonic Anhydrase II in Complex with Dual Aromatase-Steroid Sulfatase Inhibitors(,) Biochemistry, 44, 2005
1XQ8	Human micelle-bound alpha-synuclein 分子名称: Alpha-synuclein 著者 Ulmer, T.S, Bax, A, Cole, N.B, Nussbaum, R.L. 登録日 2004-10-11 公開日 2005-01-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of micelle-bound human alpha-synuclein J.Biol.Chem., 280, 2005
8B28	Structure of an intron-retention variant of the plant immune signalling protein EDS1 from Vitis vinifera 分子名称: 1,2-ETHANEDIOL, Enhanced disease susceptibility 1 著者 Voss, M, Niefind, K. 登録日 2022-09-13 公開日 2023-04-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 A splicing variant of EDS1 from Vitis vinifera forms homodimers but no heterodimers with PAD4. Protein Sci., 32, 2023
8BBO	SARS-CoV-2 Delta-RBD complexed with BA.2-36 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGH@ protein, Immunoglobulin kappa light chain, ... 著者 Zhou, D, Ren, J, Stuart, D.I. 登録日 2022-10-14 公開日 2023-03-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Rep, 42, 2023
8BNS	Crystal structure of Pif1 from Sulfurihydrogenibium sp in complex with ADP 分子名称: AAA ATPase, ADENOSINE-5'-DIPHOSPHATE 著者 Rety, S, Chen, W.F, Xi, X.G. 登録日 2022-11-14 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.24 Å) 主引用文献 Structural Studies of Pif1 Helicases from Thermophilic Bacteria. Microorganisms, 11, 2023
8BBN	SARS-CoV-2 Delta-RBD complexed with BA.2-10 and EY6A Fabs 分子名称: BA.2-10 heavy chain, BA.2-10 light chain, EY6A Heavy chain, ... 著者 Zhou, D, Ren, J, Stuart, D.I. 登録日 2022-10-14 公開日 2023-03-22 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.58 Å) 主引用文献 Rapid escape of new SARS-CoV-2 Omicron variants from BA.2-directed antibody responses. Cell Rep, 42, 2023
3MH4	HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues 分子名称: Protease do 著者 Krojer, T, Sawa, J, Huber, R, Clausen, T. 登録日 2010-04-07 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
1FEA	UNLIGANDED CRITHIDIA FASCICULATA TRYPANOTHIONE REDUCTASE AT 2.2 ANGSTROM RESOLUTION 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, TRYPANOTHIONE REDUCTASE 著者 Strickland, C, Karplus, P. 登録日 1995-07-12 公開日 1997-01-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crithidia Fasciculata Trypanothione Reductase at 1.70 A Resolution To be Published
1XVQ	Crystal structure of thiol peroxidase from Mycobacterium tuberculosis 分子名称: AMMONIUM ION, YTTRIUM (III) ION, thiol peroxidase 著者 Rho, B.S, Pedelacq, J.D, Hung, L.W, Holton, J.M, Vigil, D, Kim, S.I, Park, M.S, Terwilliger, T.C, TB Structural Genomics Consortium (TBSGC) 登録日 2004-10-28 公開日 2004-12-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Functional and Structural Characterization of a Thiol Peroxidase from Mycobacterium tuberculosis. J.Mol.Biol., 361, 2006
1FQM	X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT 分子名称: CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION 著者 Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W. 登録日 2000-09-06 公開日 2001-01-17 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II. Biochemistry, 39, 2000
3MFV	Crystal structure of human arginase I in complex with 2-aminohomohistidine 分子名称: (2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic acid, Arginase-1, MANGANESE (II) ION 著者 Di Costanzo, L, Christianson, D.W. 登録日 2010-04-04 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J.Med.Chem., 53, 2010
1XVW	Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin 分子名称: Hypothetical protein Rv2238c/MT2298 著者 Li, S, Peterson, N.A, Kim, M.Y, Kim, C.Y, Hung, L.W, Yu, M, Lekin, T, Segelke, B.W, Lott, J.S, Baker, E.N, TB Structural Genomics Consortium (TBSGC) 登録日 2004-10-28 公開日 2005-02-22 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys Peroxiredoxin J.Mol.Biol., 346, 2005
438D	STRUCTURE OF AN RNA DUPLEX R(GGGCGCUCC)2 WITH NON-ADJACENT G.U BASE PAIRS 分子名称: RNA (5'-R(*GP*GP*GP*CP*GP*CP*UP*CP*C)-3') 著者 Shi, K, Wahl, M.C, Sundaralingam, M. 登録日 1998-12-28 公開日 1999-05-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of an RNA duplex r(G GCGC CC)2 with non-adjacent G*U base pairs. Nucleic Acids Res., 27, 1999
4MTC	Crystal structure of human C53A DJ-1 分子名称: 1,2-ETHANEDIOL, Protein DJ-1 著者 Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L. 登録日 2013-09-19 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 DJ-1 Is a Copper Chaperone Acting on SOD1 Activation. J.Biol.Chem., 289, 2014

<909910911912913914915916917918919920921922923924>